ChemicalBook > CAS DataBase List > Trimethylacetic anhydride
Trimethylacetic anhydride
- Product Name
- Trimethylacetic anhydride
- CAS No.
- 1538-75-6
- Chemical Name
- Trimethylacetic anhydride
- Synonyms
- PIVALIC ANHYDRIDE;Bis(2,2-dimethylpropionic)anhydride;Pivalic anydride;Bis(pivalic)anhydride;Pivalic acid anhydride;2,2-Dimethylpropanoicanhydride;2,2-dimethylpropanoyl 2,2-dimethylpropanoate;Pivolic Anhydride;Dipivalic anhydride;PivalicAnhydride>
- CBNumber
- CB9470666
- Molecular Formula
- C10H18O3
- Formula Weight
- 186.25
- MOL File
- 1538-75-6.mol
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Trimethylacetic anhydride Property
- Boiling point:
- 193 °C(lit.)
- Density
- 0.918 g/mL at 25 °C(lit.)
- vapor pressure
- 62.1Pa at 25℃
- refractive index
- n20/D 1.409(lit.)
- Flash point:
- 135 °F
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Miscible with acetonitrile.
- form
- Liquid
- color
- Clear colorless
- Sensitive
- Moisture Sensitive
- BRN
- 386552
- InChI
- InChI=1S/C10H18O3/c1-9(2,3)7(11)13-8(12)10(4,5)6/h1-6H3
- InChIKey
- PGZVFRAEAAXREB-UHFFFAOYSA-N
- SMILES
- C(C)(C)(C)C(=O)OC(=O)C(C)(C)C
- LogP
- 2.15
- CAS DataBase Reference
- 1538-75-6(CAS DataBase Reference)
- EPA Substance Registry System
- Propanoic acid, 2,2-dimethyl-, anhydride (1538-75-6)
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Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 2920 8/PG 2
- WGK Germany
- 3
- F
- 9-13-21
- TSCA
- Yes
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29159000
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 143502
- Product name
- Trimethylacetic anhydride
- Purity
- 99%
- Packaging
- 25g
- Price
- $59
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 143502
- Product name
- Trimethylacetic anhydride
- Purity
- 99%
- Packaging
- 100g
- Price
- $176
- Updated
- 2024/03/01
TCI Chemical
- Product number
- P1414
- Product name
- Pivalic Anhydride
- Purity
- >98.0%(GC)
- Packaging
- 25mL
- Price
- $59
- Updated
- 2024/03/01
TCI Chemical
- Product number
- P1414
- Product name
- Pivalic Anhydride
- Purity
- >98.0%(GC)
- Packaging
- 250mL
- Price
- $295
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- B22983
- Product name
- Trimethylacetic anhydride, 99%
- Packaging
- 25g
- Price
- $62.1
- Updated
- 2024/03/01
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Trimethylacetic anhydride Chemical Properties,Usage,Production
Description
Trimethylacetic anhydride is a pivalic acid derivative that is used in organic synthesis. The compound's reaction mechanism is believed to be the formation of an alkanoic acid, which reacts with a hydroxyl group to form an anhydride. Trimethyl acetic anhydride has been shown to have pharmacokinetic properties and can be used as a nonsteroidal anti-inflammatory drug. This compound has also been found to have a matrix effect on crystalline cellulose and is capable of forming nitrogen-containing carboxylic acids.
Chemical Properties
clear colourless liquid
Uses
A metabolite of a double prodrug (6-dGCV-DPiv
Uses
Trimethylacetic anhydride was used:
- in solid-phase oligonucleotide synthesis
- in kinetic resolution of racemic 2-hydroxy-γ-butyrolactones with diphenylacetic acid
- as acylation and esterification reagent for anilines
- as acylation and esterification reagent for phenols
Flammability and Explosibility
Not classified
Trimethylacetic anhydride Preparation Products And Raw materials
Raw materials
Preparation Products
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Trimethylacetic anhydride Suppliers
- Tel
- --
- Fax
- --
- webmestre-substances@ineris.fr
- Country
- France
- ProdList
- 6024
- Advantage
- 58
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View Lastest Price from Trimethylacetic anhydride manufacturers
Hebei Zhuanglai Chemical Trading Co.,Ltd
- Product
- Trimethylacetic Anhydride 1538-75-6
- Price
- US $180.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20ton
- Release date
- 2024-06-05
Handan Huajun chemicals Co.,Ltd
- Product
- Pivalic anhydride 1538-75-6
- Price
- US $13.00/kg
- Min. Order
- 1kg
- Purity
- 99.0%
- Supply Ability
- 1000MT
- Release date
- 2024-01-24
airuikechemical co., ltd.
- Product
- trimethylacetic anhydride 1538-75-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 99.99%
- Supply Ability
- 20 tons
- Release date
- 2024-07-12
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