ChemicalBook > CAS DataBase List > 2-Amino-5-chlorobenzaldehyde

2-Amino-5-chlorobenzaldehyde

Product Name
2-Amino-5-chlorobenzaldehyde
CAS No.
20028-53-9
Chemical Name
2-Amino-5-chlorobenzaldehyde
Synonyms
SKL306;4-Chloro-2-formylaniline;5-CHLOROANTHRANILALDEHYDE;5-Amino-2-chlorobenzaldehyde;6-Amino-3-chlorobenzaldehyde;2-AMINO-5-CHLOROBENZALDEHYDE;Benzaldehyde,2-aMino-5-chloro-
CBNumber
CB9472549
Molecular Formula
C7H6ClNO
Formula Weight
155.58
MOL File
20028-53-9.mol
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2-Amino-5-chlorobenzaldehyde Property

Melting point:
71-73°C
Boiling point:
288.1±25.0 °C(Predicted)
Density 
1.348±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
-0.28±0.10(Predicted)
Appearance
Light yellow to yellow Solid
Water Solubility 
Slightly soluble in water.
Sensitive 
Air Sensitive
BRN 
2716096
CAS DataBase Reference
20028-53-9(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-43-36-22
Safety Statements 
26-36-36/37
HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
A3064
Product name
2-Amino-5-chlorobenzaldehyde
Purity
min. 95.0 %
Packaging
1G
Price
$70
Updated
2025/07/31
TCI Chemical
Product number
A3064
Product name
2-Amino-5-chlorobenzaldehyde
Purity
min. 95.0 %
Packaging
5G
Price
$279
Updated
2025/07/31
TRC
Product number
A617790
Product name
2-Amino-5-chlorobenzaldehyde
Packaging
25mg
Price
$130
Updated
2021/12/16
TRC
Product number
A617790
Product name
2-Amino-5-chlorobenzaldehyde
Packaging
250mg
Price
$875
Updated
2021/12/16
Oakwood
Product number
077451
Product name
2-Amino-5-chlorobenzaldehyde
Purity
95+%
Packaging
250mg
Price
$32
Updated
2021/12/16
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2-Amino-5-chlorobenzaldehyde Chemical Properties,Usage,Production

Uses

2-Amino-5-Chlorobenzaldehyde is used as a raw material in organic synthesis. It also serves as a pharmaceutical intermediate.

Synthesis

6628-86-0

20028-53-9

Example 3 The preparation of N-(4-chloro-2-formylphenyl)trifluoromethanesulfonamide (Formula 24) was carried out according to the reaction scheme shown in Figure 1. The specific steps were as follows: 6. a) To an aqueous solution (500 mL) containing Na2S2O4 (technical grade, 85%, 29.72 g, 145.09 mmol) and Na2CO3 (12.98 g, 122.46 mmol) was added dropwise over a period of 25 min at 45 °C 5-chloro-2-nitrobenzaldehyde (technical grade, 80%, 5.31 g, 22.89 mmol) to a methanol solution (100 mL). Subsequently, the reaction mixture was heated to 65 °C. After completion of the reaction, it was cooled to room temperature and extracted three times with CH2Cl2. The organic phases were combined, washed with water, dried and the solvent was concentrated under reduced pressure. The residue was filtered through a pad of silica gel (eluent was CH2Cl2/petroleum ether, 4:1) and after concentration of the solvent under reduced pressure, 2-amino-5-chlorobenzaldehyde 23 (2.12 g, 60% yield) was obtained as a yellow oil.

References

[1] Organic Letters, 2010, vol. 12, # 23, p. 5502 - 5505
[2] Patent: US2006/63841, 2006, A1. Location in patent: Page/Page column 30; 6/12
[3] Chemical Communications, 2011, vol. 47, # 36, p. 10133 - 10135
[4] Synthesis (Germany), 2016, vol. 48, # 22, p. 3985 - 3995
[5] Journal of medicinal chemistry, 1968, vol. 11, # 5, p. 946 - 949

2-Amino-5-chlorobenzaldehyde Preparation Products And Raw materials

Raw materials

Sodium dithionite Ethanol Acetic acid 5-Chloro-2-nitrobenzaldehyde Sodium carbonate

Preparation Products

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2-Amino-5-chlorobenzaldehyde Suppliers

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View Lastest Price from 2-Amino-5-chlorobenzaldehyde manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Amino-5-chlorobenzaldehyde 20028-53-9
Price
US $0.00-0.00/g
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15
Career Henan Chemical Co
Product
2-Amino-5-chlorobenzaldehyde 20028-53-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2018-08-06

20028-53-9, 2-Amino-5-chlorobenzaldehydeRelated Search:

2-Chlorobenzaldehyde ALTRENOGEST 4-Aminobenzaldehyde 2-Aminobenzaldehyde 4-Dimethylaminobenzaldehyde 3-Aminophenol Glycine 2-Amino-5-chlorobenzonitrile 6-Aminocaproic acid 2-Amino-5-chlorobenzoic acid 4-Chlorobenzaldehyde Tris(hydroxymethyl)aminomethane 3,5-Dichloroanthranilic acid 2-Chloro-N-[4-chloro-2-(2-chlorobenzoyl)phenyl]acetamide 7-CHLORO-3,4-DIHYDRO-1H-BENZO[E][1,4]DIAZEPINE-2,5-DIONE 5-Chloro-2-nitrobenzoic acid 5-Chloroisatin 2-Amino-5-chlorobenzamide

  • 2-AMINO-5-CHLOROBENZALDEHYDE
  • 5-CHLOROANTHRANILALDEHYDE
  • 6-Amino-3-chlorobenzaldehyde
  • 5-Amino-2-chlorobenzaldehyde
  • Benzaldehyde,2-aMino-5-chloro-
  • 4-Chloro-2-formylaniline
  • SKL306
  • 20028-53-9
  • Aromatic Aldehydes & Derivatives (substituted)
  • Benzaldehyde