ChemicalBook > CAS DataBase List > Sermorelin

Sermorelin

Product Name
Sermorelin
CAS No.
86168-78-7
Chemical Name
Sermorelin
Synonyms
Semorelin;SERMORELIN;Sermorellin;Sermorelin Aceta;Sermelin Acetate;Semonelin Acetale;Sermorelin USP/EP/BP;86168-78-7 Sermorelin;Sermorelin Acetate(net);Sermorelin (GHRH (1-29)
CBNumber
CB9474927
Molecular Formula
C149H246N44O42S
Formula Weight
3357.93
MOL File
86168-78-7.mol
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Sermorelin Property

Melting point:
>189°C (dec.)
alpha 
D20 -63.1° (c = 1 in 30% acetic acid)
Density 
1.45±0.1 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Acetic Acid (Slightly), Trifluoroacetic Acid (Slightly), Water (Slightly)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChI
InChI=1/C149H246N44O42S/c1-20-77(13)116(191-122(211)81(17)168-132(221)104(66-113(204)205)178-121(210)79(15)167-123(212)88(152)62-84-39-43-86(198)44-40-84)145(234)185-102(63-83-32-23-22-24-33-83)138(227)193-118(82(18)197)146(235)186-103(65-111(155)202)137(226)189-108(71-196)142(231)182-101(64-85-41-45-87(199)46-42-85)136(225)175-93(38-31-56-165-149(161)162)126(215)174-91(35-26-28-53-151)131(220)190-115(76(11)12)143(232)184-97(58-72(3)4)124(213)166-68-112(203)170-94(47-49-109(153)200)128(217)180-100(61-75(9)10)135(224)188-106(69-194)140(229)169-80(16)120(209)172-92(37-30-55-164-148(159)160)125(214)173-90(34-25-27-52-150)127(216)179-99(60-74(7)8)134(223)181-98(59-73(5)6)133(222)176-95(48-50-110(154)201)129(218)183-105(67-114(206)207)139(228)192-117(78(14)21-2)144(233)177-96(51-57-236-19)130(219)187-107(70-195)141(230)171-89(119(156)208)36-29-54-163-147(157)158/h22-24,32-33,39-46,72-82,88-108,115-118,194-199H,20-21,25-31,34-38,47-71,150-152H2,1-19H3,(H2,153,200)(H2,154,201)(H2,155,202)(H2,156,208)(H,166,213)(H,167,212)(H,168,221)(H,169,229)(H,170,203)(H,171,230)(H,172,209)(H,173,214)(H,174,215)(H,175,225)(H,176,222)(H,177,233)(H,178,210)(H,179,216)(H,180,217)(H,181,223)(H,182,231)(H,183,218)(H,184,232)(H,185,234)(H,186,235)(H,187,219)(H,188,224)(H,189,226)(H,190,220)(H,191,211)(H,192,228)(H,193,227)(H,204,205)(H,206,207)(H4,157,158,163)(H4,159,160,164)(H4,161,162,165)/t77-,78-,79-,80-,81-,82+,88-,89-,90-,91-,92-,93-,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,115-,116-,117-,118-/s3
InChIKey
BVLCEKWPOSAKSZ-YQMCHIOTSA-N
SMILES
[C@H](C(=O)N[C@@]([H])([C@H](O)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CO)C(=O)N[C@H](C(=O)N)CCCNC(N)=N)CC1C=CC(O)=CC=1)(NC(=O)[C@]([H])([C@@H](C)CC)NC(=O)[C@H](C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC1C=CC(O)=CC=1)CC1C=CC=CC=1 |&1:0,4,6,12,20,26,30,41,50,57,69,78,86,92,97,108,117,125,133,142,150,151,158,166,172,194,196,203,208,216,221,r|
CAS DataBase Reference
86168-78-7(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G6771
Product name
Growth Hormone Releasing Factor Fragment 1-29 amide human
Purity
≥97% (HPLC)
Packaging
1mg
Price
$701.48
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
SHG0000180
Product name
SERMORELIN
Purity
95.00%
Packaging
0.5MG
Price
$600.6
Updated
2021/12/16
DC Chemicals
Product number
DC10321
Product name
Sermorelin
Purity
>98%
Packaging
250mg
Price
$1100
Updated
2021/12/16
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Sermorelin Chemical Properties,Usage,Production

Description

Sermorelin is licensed as a diagnostic test for secretion of growth hormone. It is also used for the treatment of growth hormone deficiency in children. However, products containing sermorelin were withdrawn from the United States market by the manufacturer in November 2002.

Uses

Sermorelin is a xanthine oxidase inhibitor and a peptide hormone that stimulates release of the growth hormon. Sermorelin Acetate, was used for characterization of a growth hormone-releasing factor from a human pancreatic islet tumor. It is also used to diagnose and treat poor growth in children. It is sometimes used off-label to treat hGH deficiency in adults.

Definition

Sermorelin is an analogue of growth hormone-releasing hormone (GHRH) primarily used for diagnostic purposes. It is a 29-amino acid-containing fragment of endogenous human GHRH, also represented as GHRH (1–29). Sermorelin is the shortest fully functional synthetic fragment of GHRH. It was marketed under the trade name of Geref by Serono Laboratories, but the FDA recently listed it as a “discontinued drug product.”

brand name

Geref,Gerel

benefits

The benefits of sermorelin include: Improved body composition, muscle function, and strength; Faster and efficient healing of wounds; Reduced body fat, especially abdominal fat; Enhanced immune system, bone health, and cardiovascular function; Improved sleep quality, mood, and mental clarity.

Mechanism of action

Sermorelin binds to the growth hormone-releasing hormone receptor (GHRH), mimicking the effects of the full-length GHRH in promoting growth hormone secretion.

Side effects

The most common side effect of sermorelin is caused by its injection under your skin. You may experience any of the following at the site of injection:
irritation
itching
sensitivity
swelling
pain
redness

Drug interactions

Sermorelin may interact with other medications. Drug interactions that may interfere with sermorelin include:
thyroid medications (levothyroxine)
cyclooxygenase inhibitors (aspirin)
glucocorticoids (prednisone)
insulin
muscarinic antagonists (atropine)
somatostatin-containing drugs or drugs that affect somatostatin (levodopa)

Sermorelin Preparation Products And Raw materials

Raw materials

Preparation Products

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Sermorelin Suppliers

China 236 Europe 2 France 1 Germany 3 India 5 Japan 1 South Korea 1 Switzerland 1 United Kingdom 1 United States 19 Global 270
Cellmano Biotech Limited
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+86-13393959797 +86-13393959797
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Wuhan Xinyan Biotechnology Co., Ltd.
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027-17764015852 17764015852
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Fuan Bio
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Chemsky（shanghai）International Co.,Ltd.
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AN PharmaTech Co Ltd
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Raw material medicin reagent co.,Ltd
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Shanghai Chaolan Chemical Technology Center
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Amadis Chemical Company Limited
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Twochem Co.Ltd.
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UHN Shanghai Research & Development Co., Ltd.
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Nextpeptide Inc
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View Lastest Price from Sermorelin manufacturers

Wuhan JiyunZen Tech Co., Ltd.
Product
Sermorelin 86168-78-7
Price
US $5.00-0.50/Gram
Min. Order
1Gram
Purity
99% hplc
Supply Ability
500TONS
Release date
2025-11-20
TsurgeX Pharmaceutical Technology Co., Ltd.
Product
Sermorelin 86168-78-7
Price
US $670.68-402.41/g
Min. Order
1g
Purity
99%
Supply Ability
1 tons
Release date
2025-08-26
Chongqing Soarwin Technology Co., Ltd
Product
Sermorelin 86168-78-7
Price
US $0.00-0.00/Box
Min. Order
1Box
Purity
99%
Supply Ability
1000 boxes
Release date
2025-08-20

86168-78-7, SermorelinRelated Search:

Taltirelin Degarelix BUSERELIN Elcatonin Calcitonin salmon Nesiritide acetate Thymopentin Triptorelin acetate Pramlintide acetate GLP-1 (7-37) Eptifibatide Thymalfasin Leuprorelin GROWTH HORMONE, HUMAN SERMORELIN (HUMAN) Sermorelin Sermorelin acetate SERMORELIN (HUMAN)

  • SERMORELIN
  • YADAIFTNSYRKVLGQLSARKLLQDIMSR-NH2
  • TYR-ALA-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-NH2
  • TYR-ALA-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-NH2 HUMAN
  • growth hormone releasing factor*fragment 1-29 ami
  • H-TYR-ALA-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-SER-ARG-NH2
  • GROWTH HORMONE RELEASING FACTOR (1-29), AMIDE, HUMAN
  • GRF (1-29) AMIDE (HUMAN)
  • GROWTH HORMONE RELEASING FACTOR, FRAGMENT 1-29 AMIDE
  • GROWTH HORMONE RELEASING FACTOR FRAGMENT 1-29 AMIDE HUMAN
  • GHRF (1-29), AMIDE, HUMAN
  • Green tea powdered extract
  • SERMORELIN, GROWTH HORMONE RELEASING FACTOR FRAGMENT 1-29 AMIDE
  • somatoliberin fragment 1-29 amide, human
  • Sermorelin Aceta
  • TYR-ALA-ASP-ALA-ILE-PHE-THR-ASN-SER-TYR-ARG-LYS-VAL-LEU-GLY-GLN-LEU-SER-ALA-ARG-LYS-LEU-LEU-GLN-ASP-ILE-MET-ASN-ARG-GLN-GLN-GLY-GLU-ARG-ASN-GLN-GLU-GLN-GLY-ALA-LYS-VAL-ARG-LEU-NH2: YADAIFTNSYRKVLGQLSARKLLQDIMNRQQGERNQEQGAKVRL-NH2
  • [D-Ala2]-Growth Hormone Releasing Factor, GRF (1-29), amide, human
  • GRF (1-29) aMide (huMan) SerMorelin
  • Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Thr-Arg-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH{2}
  • 1-29-SOMATOLIBERIN (HUMAN PANCREATIC ISLET), 29-L-ARGININAMIDE-
  • Sermelin Acetate
  • Semorelin
  • Sermorelin,GHRH (1-29),Growth Hormone Releasing Factor Fragment 1-29 amide human, BR
  • Peptides Sermorelin Base Sermorelin Acetate
  • Sermorelin USP/EP/BP
  • 86168-78-7 Sermorelin
  • Sermorelin Acetate(net)
  • Sermorelin (GRF (1-29) amide)
  • Sermorelin，GHRH (1-29)，Growth Hormone Releasing Factor Fragment 1-29 amide human
  • Sermorellin
  • Sermorelin 5mg 10mg(GHRH (1-29)
  • Sermorelin (GHRH (1-29)
  • Semonelin Acetale
  • 86168-78-7
  • 86186-78-7
  • C149H246N44O42S
  • Releasing Factors
  • Peptides
  • GH-RH
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Peptide
  • Amino Acid Derivatives
  • GH-RHObesity Research
  • GH-RHPeptides for Cell Biology
  • Growth Hormone Releasing Factors
  • Neuropeptides
  • Neurotransmission (Obesity)
  • Releasing Factors
  • Sermorelin
  • 86168-78-7