Vanillylacetone
Food flavorings Content Analysis Toxicity Limited use- Product Name
- Vanillylacetone
- CAS No.
- 122-48-5
- Chemical Name
- Vanillylacetone
- Synonyms
- ZINGERONE;4-(4-HYDROXY-3-METHOXYPHENYL)BUTAN-2-ONE;ZINGIBERONE;Gingerone;Zingarone;FEMA 3124;NSC 15335;zingherone;[0]-Paradol;(0)-paradol
- CBNumber
- CB9479326
- Molecular Formula
- C11H14O3
- Formula Weight
- 194.23
- MOL File
- 122-48-5.mol
Vanillylacetone Property
- Melting point:
- 40-41 °C(lit.)
- Boiling point:
- 141 °C0.5 mm Hg(lit.)
- Density
- 1.14 g/mL at 25 °C(lit.)
- refractive index
- n20/D 1.541(lit.)
- FEMA
- 3124 | ZINGERONE
- Flash point:
- >230 °F
- storage temp.
- Sealed in dry,2-8°C
- solubility
- Acetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 10.03±0.20(Predicted)
- color
- White to Pale Yellow
- Odor
- at 100.00 %. sweet spicy phenolic ginger vanilla woody
- Odor Type
- spicy
- biological source
- synthetic
- JECFA Number
- 730
- Merck
- 14,10166
- InChIKey
- OJYLAHXKWMRDGS-UHFFFAOYSA-N
- LogP
- 0.64
- CAS DataBase Reference
- 122-48-5(CAS DataBase Reference)
- NIST Chemistry Reference
- 2-Butanone, 4-(4-hydroxy-3-methoxyphenyl)-(122-48-5)
- EPA Substance Registry System
- 2-Butanone, 4-(4-hydroxy-3-methoxyphenyl)- (122-48-5)
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36
- WGK Germany
- 2
- RTECS
- EL8900000
- TSCA
- Yes
- HS Code
- 29333999
- Hazardous Substances Data
- 122-48-5(Hazardous Substances Data)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H303May be harmfulif swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- W312420
- Product name
- Vanillylacetone
- Purity
- ≥98%, natural (US), FG
- Packaging
- 1 unit
- Price
- $64.1
- Updated
- 2025/07/31
- Product number
- W312420
- Product name
- Vanillylacetone
- Purity
- ≥98%, natural (US), FG
- Packaging
- 1 unit
- Price
- $64.1
- Updated
- 2025/07/31
- Product number
- W312420
- Product name
- Vanillylacetone
- Purity
- ≥98%, natural (US), FG
- Packaging
- 100g
- Price
- $199
- Updated
- 2025/07/31
- Product number
- W312420
- Product name
- Vanillylacetone
- Purity
- ≥98%, natural (US), FG
- Packaging
- 500g
- Price
- $576
- Updated
- 2025/07/31
- Product number
- W312401
- Product name
- Vanillylacetone
- Purity
- ≥96%, FG
- Packaging
- 1 unit
- Price
- $54.6
- Updated
- 2025/07/31
Vanillylacetone Chemical Properties,Usage,Production
Food flavorings
Vanillylacetone also called zingerone , is a food spice which is allowed to be prepared appropriately according to production needs by Chinese "Sanitary Standards of Using Food Additives" (GB 2760-1996),its chemical name is 4-(4-hydroxy 3-methoxyphenyl)-2-butanone. Yellow or light amber crystal (acetone, petroleum ether or ethyl ether-petroleum ether), at room temperature, after long time ,it becomes to a viscous liquid.It has a strong irritating odor like spicy ginger and ginger-like pungent taste,it has a sweet, spicy, full-bodied and deep floral aroma, fragrance lasts for a long time. The relative density is 1.138~1.139 (25 ℃), melting point 40~41 ℃, boiling point 290 ℃ (102 ℃), refractive index 1.544~1.545. It can be dissolved in 50% ethanol in 1:1 ratio , slightly soluble in water and petroleum ether, soluble in dilute alkali. In the steam it slowly evaporates. When heated ,it can deoxidate silver nitrate ammonia solution; and it can react with an alcohol solution of ferric chloride to turn to green. It is derived from the Zingiber officinale essential oils , Vanillylacetone is the main constituent of ginger oil . After the condensation reaction of vanillin and acetone,it is obtained through hydrogenation .it is used as a full-bodied flavor sweeteners and edible flavorings. In the perfumed products ,it can have a "leather", "tobacco" flavor. It is not easy to change color.
Vanillylacetone can be used in the formulation of flavors, it is mainly used as sweeteners for rich aromas and flavors , in very small quantities, the application range is very small. IFRA has no restrictions.
Vanillylacetone is recognized as GRAS by FEMA , FEMA number is 3124, and it is approved by the FDA for human consumption,it is included in the artificial flavor table by the Council of Europe in the level of 15mg/kg dosage which can be used in foods and is not harmful to human health . Vanillylacetone can be used for food flavor and seasoning product formulations.
FEMA provides: Vanillylacetone highest reference amount is soft drinks, 6.9mg/kg; ice cream, ices, 7.8mg/kg; candy, 11mg/kg; baked goods, 11mg/kg; chewing gum, 15mg/kg.
Content Analysis
Use gas chromatography (GT-10-4) nonpolar column method for the determination.
Toxicity
GRAS (FEMA).
LD502.58g/kg (rat, dictation).
Limited use
FEMA (mg/kg): Soft drinks 6.9; cold:7.8 ; confectionery, bakery products, 11.0; Chewing Gum:15.0
FDA, §172.515: the right amount limit.
Chemical Properties
Zingerone has a strong, pungent odor reminiscent of ginger. It has a sharp taste, similar to ginger.
Chemical Properties
White solid. Soluble in ether; sparingly soluble in water and petroleum ether.
Occurrence
Reported found in the essential oil of Zingiber officinale. Also reported found in cranberry, raspberry, ginger and mango.
Uses
Vanillylacetone is a phenolic compound that naturally occurs in cranberry and ginger. Studies shows that Vanillylacetone exhibits variable cytotoxic, cytoprotective and antioxidant activity against liver and human tumor cells. Vanillylacetone is also used in herbal medicine for various purposes.
Uses
In fragrances, flavors and cosmetics; in artificial spice oils.
Definition
ChEBI: A ketone that is 4-phenylbutan-2-one in which the phenyl ring is substituted at positions 3 and 4 by methoxy and hydroxy groups respectively. The major pungent component in ginger.
Preparation
By condensation of vanillin with acetone followed by hydrogenation.
Aroma threshold values
Aroma characteristics at 10.0%: low impacting, creamy, spicy eugenol clove-like with a slight balsamic vanilla-like note.
Taste threshold values
Taste characteristics at 80 ppm: spicy with a biting, lingering heat. Taste characteristics at 20 ppm in 5% sugar solution: smooth, sweet, creamy and warm, spicy clove with a slight lingering burning bite.
Biological Activity
Taste at 20 ppm in 5%
Safety Profile
Moderately toxic by ingestion. A skin irritant. A flammable liquid. When heated to decomposition it emits acrid smoke and irritating fumes.
Vanillylacetone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Vanillylacetone manufacturers
- Product
- Vanillylacetone 122-48-5
- Price
- US $10.00/KG
- Min. Order
- 100KG
- Purity
- 99%
- Supply Ability
- 100 mt
- Release date
- 2024-12-06
- Product
- Vanillylacetone 122-48-5
- Price
- US $1000.00-800.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000
- Release date
- 2024-08-16
- Product
- Vanillylacetone 122-48-5
- Price
- US $45.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2024-12-09