ChemicalBook > CAS DataBase List > Isorhamnetin 3,7-O-diglucoside

Isorhamnetin 3,7-O-diglucoside

Product Name
Isorhamnetin 3,7-O-diglucoside
CAS No.
6758-51-6
Chemical Name
Isorhamnetin 3,7-O-diglucoside
Synonyms
Isorhamnetin-3,7-diglucoside;Isorhamnetin 3,7-O-diglucoside;Isorhamnetin-3,7-O-β-diglucopyranoside;isorhamnetin 3,7-O-di-β-D-glucopyranoside;Isorhamnetin 3,7-di-O-β-D-glucopyranoside;4H-1-Benzopyran-4-one, 3,7-bis(β-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxy-3-methoxyphenyl)-
CBNumber
CB94819546
Molecular Formula
C28H32O17
Formula Weight
640.55
MOL File
6758-51-6.mol
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Isorhamnetin 3,7-O-diglucoside Property

Boiling point:
1016.2±65.0 °C(Predicted)
Density 
1.79±0.1 g/cm3(Predicted)
pka
5.77±0.40(Predicted)
form 
Solid
color 
Off-white to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

AvaChem
Product number
4265
Product name
Isorhamnetin 3,7-O-diglucoside
Packaging
1mg
Price
$119
Updated
2021/12/16
Arctom
Product number
CFN91130
Product name
Isorhamnetin3,7-O-diglucoside
Packaging
5mg
Price
$288
Updated
2021/12/16
AvaChem
Product number
4265
Product name
Isorhamnetin 3,7-O-diglucoside
Packaging
5mg
Price
$390
Updated
2021/12/16
AvaChem
Product number
4265
Product name
Isorhamnetin 3,7-O-diglucoside
Packaging
10mg
Price
$590
Updated
2021/12/16
AvaChem
Product number
4265
Product name
Isorhamnetin 3,7-O-diglucoside
Packaging
20mg
Price
$890
Updated
2021/12/16
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Isorhamnetin 3,7-O-diglucoside Chemical Properties,Usage,Production

Uses

Isorhamnetin 3,7-di-O-β-D-glucopyranoside, a major flavonoid compound, is metabolized in vivo by intestinal bacteria to isorhamnetin and that isorhamnetin plays an important role as an antioxidant[1].

in vivo

Isorhamnetin 3,7-di-O-β-D-glucopyranoside (10 or 20 mg/kg of body weight/day for 10 days; p.o.) to rats with streptozotocin-induced diabetes significantly reduced serum levels of glucose and 5-(hydroxymethyl)furfural (5-HMF), which is glycosylated with hemoglobin and is an indicator of oxidative stress[1].

Animal Model:Male Wistar rats (5 weeks old, 120-130 g) (STZ-induced diabetic rats had higher glucose and 5-HMF levels than normal rats)[1]
Dosage:10 or 20 mg/kg of body weight
Administration:P.o.; daily for 10 days
Result:The serum glucose levels of rats given 10 and 20 mg of orally were 510.1 and 492.4 mg/dL, respectively, whereas the control level was 574.2 mg/dL.

References

[1] Yokozawa T, et al. Antioxidant effects of isorhamnetin 3,7-di-O-beta-D-glucopyranoside isolated from mustard leaf (Brassica juncea) in rats with streptozotocin-induced diabetes. J Agric Food Chem. 2002;50(19):5490-5495. DOI:10.1021/jf0202133

Isorhamnetin 3,7-O-diglucoside Preparation Products And Raw materials

Raw materials

Preparation Products

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