4-BROMO-A23187

Product Name: 4-BROMO-A23187
CAS No.: 76455-48-6
Chemical Name: 4-BROMO-A23187
Synonyms: 4-BR-A23187;4-BROMO-A23187;A23187, 4-BROMO;4-BROMOCALCIMYCIN;4-BROMO-ANTIBIOTIC;CALCIMYCIN, 4-BROMO;4-BROMOCALCIMYCIN A23187;4-BROMO-ANTIBIOTIC A23187;ANTIBIOTIC A-23187, 4-BROMO;4-BROMO-CALCIUM IONOPHORE A23187
CBNumber: CB9490107
Molecular Formula: C29H36BrN3O6
Formula Weight: 602.52
MOL File: 76455-48-6.mol

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4-BROMO-A23187 Property

Boiling point:: 735.4±60.0 °C(Predicted)
Density: 1.43±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: ethanol: 20 mg/mL
pka: 15.14±0.50(Predicted)
form: powder
color: yellow
InChIKey: LDXQFZZGVTWFCF-FHYGWRBKSA-N
SMILES: CNc1c(Br)cc2oc(C[C@H]3O[C@@]4(CC[C@H]3C)O[C@@H]([C@H](C)C[C@H]4C)[C@H](C)C(=O)c5ccc[nH]5)nc2c1C(O)=O

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Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39-36/37
WGK Germany: 3
HS Code: 29419090
Storage Class: 13 - Non Combustible Solids
Hazard Classifications: Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B7272
Product name: 4-Bromo-calcium Ionophore A23187
Purity: powder
Packaging: 1mg
Price: $292.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 100107
Product name: A23187, 4-Bromo-
Packaging: 1mg
Price: $318
Updated: 2025/07/31

Cayman Chemical

Product number: 20438
Product name: 4-bromo A23187
Purity: ≥95%
Packaging: 1mg
Price: $117
Updated: 2024/03/01

Cayman Chemical

Product number: 20438
Product name: 4-bromo A23187
Purity: ≥95%
Packaging: 5mg
Price: $463
Updated: 2024/03/01

Cayman Chemical

Product number: 20438
Product name: 4-bromo A23187
Purity: ≥95%
Packaging: 10mg
Price: $750
Updated: 2024/03/01

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4-BROMO-A23187 Chemical Properties,Usage,Production

Chemical Properties

Yellow powder

Uses

4-Bromo-calcium Ionophore A23187 has been used for the activation of Ca²⁺/calmodulin kinase II (CaMKII) in HeLa cell line. It has also been used as a calcium mobilizer to investigate its effect on superoxide dismutase 1 (SOD1) aggregates in VSC 4.1 cells.

Uses

4-Bromo-A23187 is an ionophore that transports Zn2+ and Mn2+ with high selectivity over Ca2+.

Biochem/physiol Actions

4-Bromo-calcium Ionophore A23187 is a modulator of apoptosis. It inhibits apoptosis in a concentration dependent manner in neutrophils which are aging in vitro and increases the intracellular Ca2+ levels.

4-BROMO-A23187 Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMO-A23187 Suppliers

China 63 Germany 2 Japan 1 Switzerland 2 United Kingdom 3 United States 16 Global 87

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76455-48-6, 4-BROMO-A23187Related Search:

2-AMINO-3-BROMOBENZOIC ACID 2-Acetyl pyrrole 2-ETHYL-BENZOOXAZOLE 1,7-DIOXASPIRO[5.5]UNDECANE A23187 2-PROPIONYLPYRROLE 4-ISOBUTOXY-2-BUTANONE 6-BROMOBENZOXAZOLE 2-BROMO-6-METHYLANILINE 5-AMINOBENZOOXAZOLE 6-BROMO-2-METHYLBENZODOXAZOLE 2-ETHYL-1,3-BENZOXAZOL-5-AMINE 4-BROMO-A23187 2-METHYL-1,3-BENZOXAZOL-5-AMINE 1,1-DI(2-METHYLBUTOXY)ETHANE 1,1-DI-ISOBUTOXYPROPANE 4-SEC-BUTOXY-2-BUTANONE 2-BUTYL-1,3-BENZOXAZOL-5-AMINE

A23187, 4-Bromo- - CAS 76455-48-6 - Calbiochem

ANTIBIOTIC A-23187, 4-BROMO

CALCIMYCIN, 4-BROMO

4-BROMO-A23187

4-BROMO-ANTIBIOTIC

4-BROMO-ANTIBIOTIC A23187

4-BROMOCALCIMYCIN

4-BROMOCALCIMYCIN A23187

4-BROMO-CALCIUM IONOPHORE A23187

4-BR-A23187

A23187, 4-BROMO

4-BROMO-CALCIUM IONOPHORE A23187FREE ACI D

4-Bromo-A23187, 4-Bromo-calcimycin

6-broMo-5-(MethylaMino)-2-(((2R,3R,6S,8S,9R,11R)-3,9,11-triMethyl-8-((S)-1-oxo-1-(1H-pyrrol-2-yl)propan-2-yl)-1,7-dioxaspiro[5.5]undecan-2-yl)Methyl)benzo[d]oxazole-4-carboxylic acid

4-BroMo A-23187, free acid [4-BroMo-calciuM Ionophore A23187], [Antibiotic A-23187, 4-BroMo]

4 Bromo A23187,4Bromo A23187,4-Bromo A-23187

4-Benzoxazolecarboxylic acid, 6-bromo-5-(methylamino)-2-[[(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl]methyl]-

76455-48-6

C29H36BrN3O6

BioChemical

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