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Protoporphyrin IX dimethyl ester

Product Name
Protoporphyrin IX dimethyl ester
CAS No.
5522-66-7
Chemical Name
Protoporphyrin IX dimethyl ester
Synonyms
Protoporphyrin dimethyl;dimethyl protoporphyrin IX;Protoporphyrin IX diMethyl es;Protoporphyrin IX dimethyl ester;Dimethylprotoporphyrin IX dimethyl ester;Protoporphyrin IX dimethyl ester, ≥95%(HPLC);Protoporphyrin IX dimethyl ester ~90% (HPLC);PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN;dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21h,23h-porphine-2,18-dipropionate;dimethyl 3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionate
CBNumber
CB9497515
Molecular Formula
C36H38N4O4
Formula Weight
590.71
MOL File
5522-66-7.mol
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Protoporphyrin IX dimethyl ester Property

Melting point:
225-228 °C(lit.)
Boiling point:
1017.0±65.0 °C(Predicted)
Density 
1.220±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
DMSO: soluble
form 
crystal
color 
purple
BRN 
381574
Stability:
Light Sensitive
InChIKey
WASRLAPXOHTNAX-MFBGAUBSSA-N
SMILES
C(C1=C(C2=CC3=NC(=CC4=C(C=C)C(C)=C(N4)C=C4C(C)=C(CCC(=O)OC)C(=N4)C=C1N2)C(C)=C3C=C)C)CC(=O)OC |c:7,t:3,18,32|
EPA Substance Registry System
21H,23H-Porphine-2,18-dipropanoic acid, 7,12-diethenyl-3,8,13,17-tetramethyl-, dimethyl ester (5522-66-7)
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Safety

WGK Germany 
3
8-10-23
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H320Causes eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
09626
Product name
Protoporphyrin IX dimethyl ester
Purity
~90% (HPLC)
Packaging
100mg
Price
$187.15
Updated
2025/07/31
TCI Chemical
Product number
D6148
Product name
Protoporphyrin IX Dimethyl Ester
Packaging
100MG
Price
$183
Updated
2025/07/31
Strem Chemicals
Product number
07-1850
Product name
Protoporphyrin IX, dimethyl ester
Packaging
100mg
Price
$87
Updated
2024/03/01
Strem Chemicals
Product number
07-1850
Product name
Protoporphyrin IX, dimethyl ester
Packaging
500mg
Price
$308
Updated
2024/03/01
TRC
Product number
P838900
Product name
Protoporphyrin IX dimethyl ester
Packaging
1g
Price
$425
Updated
2021/12/16
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Protoporphyrin IX dimethyl ester Chemical Properties,Usage,Production

Chemical Properties

Protoporphyrin IX dimethyl ester is a dark purple powder. Solubility: soluble in DMSO, acetone, and chloroform.

Uses

Protoporphyrin IX Dimethyl Ester is a derivative of Protoporphyrin IX (P839138), which is an important precursor to biologically essential prosthetic groups such as heme, cytochrome c, and chlorophylls.

Definition

ChEBI: Dimethylprotoporphyrin IX dimethyl ester is a member of porphyrins.

Purification Methods

The crude dimethyl ester (1g) in CHCl3 (200 mL) is mixed with pet ether (b 70-90o, 600mL), and any porphyrin (m > 260o) which is insoluble in this mixture is filtered off. The filtrate is passed through a column of CaCO3 [from CaCO3 (130g) which is kept overnight in a mixture of CHCl3/pet ether (b 70-90o, 1:3), and the slurry is poured into a glass tube (2.5 x 26cm) to form the column]. After all the filtrate is applied, the column is eluted with a solution of CHCl3/pet ether (b 70-90o, 1:3). All the coloured eluates are collected, evaporated at room temperature in a vacuum to give a residue (0.8g), m 208-211o. The residue (0.8g) in CHCl3 (66mL) is heated briefly to its boiling point, then boiling MeOH (198mL) is added immediately to it. The mixture is allowed to cool to room temperature, refrigerated for 2days and the solid is filtered off. The solid is washed on the filter funnel with CHCl3/MeOH (1:9, 50mL) and dried at 50o/vacuum (yield 0.62-0.66g). It can also be recrystallised by dissolving in as little hot dry *C6H6 as possible and left overnight at 20o, m 228-230o. It has also been purified by dissolving (0.4g) in CHCl3 (33mL) by boiling for a few minutes, then diluting with boiling MeOH (100mL) and refrigerating for 2days. The crystals are collected, washed with CHCl3/MeOH (1:9) and dried at 50o in a vacuum (yield 0.3g). The UV has max at 631, 576, 541, 506 and 407nm in CHCl3 and 601, 556 and 406nm in 25% HCl. [Ramsey Biochemical Preparations 3 39 1953, Beilstein 26 III/IV 3052.]

Protoporphyrin IX dimethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Protoporphyrin IX dimethyl ester Suppliers

Aladdin Scientific
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United States Biological
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Combi-Blocks Inc.
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Strem Chemicals, Inc.
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Riedel-de Haen AG
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Frontier Scientific, Inc.
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Alfa Chemistry
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View Lastest Price from Protoporphyrin IX dimethyl ester manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
Protoporphyrin IX dimethyl ester 5522-66-7
Price
US $10.00/KG
Min. Order
100KG
Purity
99%
Supply Ability
100 mt
Release date
2024-11-25
Shaanxi Dideu New Materials Co. Ltd
Product
Protoporphyrin IX dimethyl ester 5522-66-7
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
95.0%
Supply Ability
10000KGS
Release date
2024-11-11
Hebei Chuanghai Biotechnology Co,.LTD
Product
Protoporphyrin IX dimethyl ester 5522-66-7
Price
US $1.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 ton
Release date
2024-08-05

5522-66-7, Protoporphyrin IX dimethyl esterRelated Search:


  • Protoporphyrin IX dimethyl ester, ≥95%(HPLC)
  • methyl 3-[8,13-di(ethenyl)-18-(3-methoxy-3-oxo-propyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate
  • methyl 3-[8,13-di(ethenyl)-18-(3-methoxy-3-oxopropyl)-3,7,12,17-tetramethyl-22,23-dihydroporphyrin-2-yl]propanoate
  • Protoporphyrin IX diMethyl es
  • 21H,23H-Porphine-2,18-dipropanoicacid, 7,12-diethenyl-3,8,13,17-tetraMethyl-, 2,18-diMethyl ester
  • ProtoporphyrinIX dimethyl ester,Dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionate, Ooporpyhrin dimethyl ester
  • dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21h,23h-porphine-2,18-dipropionate
  • 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-Porphine-2,18-dipropanoic acid- 2,18-dimethyl ester
  • Dimethylprotoporphyrin IX dimethyl ester
  • dimethyl protoporphyrin IX
  • Ooporpyhrin dimethyl ester, Dimethyl 8,13-divinyl-3,7,12,17-tetramethyl-21H,23H-porphine-2,18-dipropionate
  • 3,8,13,17-Tetramethyl-7,12-diethenyl-21H,23H-porphyrin-2,18-dipropionic acid dimethyl ester
  • 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphyrin-2,18-bis(propionic acid methyl) ester
  • Protoporphyrin dimethyl
  • 3-[18-(3-keto-3-methoxy-propyl)-3,7,12,17-tetramethyl-8,13-divinyl-22,23-dihydroporphin-2-yl]propionic acid methyl ester
  • dimethyl 3,8,13,17-tetramethyl-7,12-divinyl-21H,23H-porphine-2,18-dipropionate
  • PROTOPORPHYRIN IX DIMETHYL ESTER FROM*OX HEMIN
  • Protoporphyrin IX dimethyl ester
  • Protoporphyrin IX dimethyl ester ~90% (HPLC)
  • Dimethyl 3,3'-(3,8,13,17-tetramethyl-7,12-divinylporphyrin-2,18-diyl)dipropionate
  • 2,18-Dimethyl 7,12-diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2,18-dipropanoate
  • 5522-66-7
  • porphine (porphyrin) ligand