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METHOXYVERAPAMIL HYDROCHLORIDE

Product Name
METHOXYVERAPAMIL HYDROCHLORIDE
CAS No.
16662-47-8
Chemical Name
METHOXYVERAPAMIL HYDROCHLORIDE
Synonyms
C13764;dl-D 600;Lu 30-029;CoMpound D 600;Methoxyverapamil;Zeatin Impurity 27;D 600 (vasodilator);(+/-)-Methoxyverapamil;(+/-)-MethoxyverapamilHydrochloride;(±)-Methoxyverapamil hydrochloride Solution, 100ppm
CBNumber
CB9498264
Molecular Formula
C28H40N2O5
Formula Weight
484.63
MOL File
16662-47-8.mol
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METHOXYVERAPAMIL HYDROCHLORIDE Property

Boiling point:
605.9±55.0 °C(Predicted)
Density 
1.068±0.06 g/cm3(Predicted)
refractive index 
nD25 1.5402
storage temp. 
Store at -20°C
solubility 
DMSO: 100 mg/mL (206.34 mM)
form 
White to off-white solid.
pka
8.96±0.50(Predicted)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
M5644
Product name
(±)-Methoxyverapamil hydrochloride
Purity
≥98%
Packaging
50mg
Price
$156
Updated
2024/03/01
Sigma-Aldrich
Product number
M5644
Product name
(±)-Methoxyverapamil hydrochloride
Purity
≥98%
Packaging
250mg
Price
$611
Updated
2024/03/01
TRC
Product number
M271768
Product name
(+/-)-Methoxyverapamil
Packaging
100mg
Price
$1200
Updated
2021/12/16
Matrix Scientific
Product number
097175
Product name
5-((3,4-Dimethoxyphenethyl)(methyl)amino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile
Purity
95+%
Packaging
1g
Price
$1647
Updated
2021/12/16
ChemScene
Product number
CS-0002968
Product name
Gallopamil
Purity
>98.0%
Packaging
5mg
Price
$90
Updated
2021/12/16
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METHOXYVERAPAMIL HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

(±)-Methoxyverapamil hydrochloride has been used:

  • as calcium channel antagonist in Schistosoma mansoni parasite
  • as calcium entry blocker in cultured macrophages
  • in the inhibition of L-type voltage gated Ca2+-channels

Definition

ChEBI: Gallopamil is a member of benzenes and an organic amino compound.

General Description

Methoxyverapamil is a calmodulin antagonist. It controls flagellar glycoprotein redistribution by modulating calcium signalling. Methoxyverapamil impacts the effect of intracellular calcium levels and affects the sperm capacitation function.

Biochem/physiol Actions

Blocks L-type Ca2+ channels

Side effects

Gallopamil has a distinctly stronger effect than verapamil but a similar activity profile , .

METHOXYVERAPAMIL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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METHOXYVERAPAMIL HYDROCHLORIDE Suppliers

China 24 Germany 1 Switzerland 2 United Kingdom 1 United States 8 Global 36
Chembest Research Laboratories Limited
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16662-47-8, METHOXYVERAPAMIL HYDROCHLORIDERelated Search:

(+)-METHOXYVERAPAMIL HYDROCHLORIDE Gabapentin Flunarizine dihydrochloride Isradipine Cilnidipine Ryanodine Nimodipine CHARYBDOTOXIN Nicardipine hydrochloride DOTARIZINE (S)-Verapamilamide Nifedipine OMEGA-AGATOXIN TK Vernakalant Impurity 3 ((3S,1'R,2'S)-Isomer) N-methylsulfamide Vernakalant Impurity 4 ((3S,1'S,2'R)-Isomer) KPKUVVDIZJKERG-WGVGGRBOSA-N D 517-d7 Hydrochloride (VerapaMil IMpurity)

  • 5-[(3,4-Dimethoxyphenethyl)methylamino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile
  • 5-[[2-(3,4-Dimethoxyphenyl)ethyl](methyl)amino]-2-isopropyl-2-(3,4,5-trimethoxyphenyl)pentanenitrile
  • Methoxyverapamil
  • C13764
  • 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile
  • 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-isopropyl-2-(3,4,5-triMethoxyphenyl)pentanenitrile HCl
  • CoMpound D 600
  • D 600 (vasodilator)
  • dl-D 600
  • Lu 30-029
  • (±)-α-[3-[(2-(3,4-dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
  • D600, Gallopamil, (±)-α-[3-[(2-(3,4-Dimethoxyphenyl)ethyl)methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)benzeneacetonitrile hydrochloride
  • α-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-isopropylbenzeneacetonitrile
  • α-[3-[N-[2-(3,4-Dimethoxyphenyl)ethyl]-N-methylamino]propyl]-3,4,5-trimethoxy-α-isopropylbenzeneacetonitrile
  • (+/-)-METHOXYVERAPAMIL HYDROCHLORIDE (D6 00) (GALLOPAMIL)
  • (±)-Methoxyverapamil hydrochloride Solution, 1000ppm
  • (±)-Methoxyverapamil hydrochloride Solution, 100ppm
  • Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)-
  • (+/-)-MethoxyverapamilHydrochloride
  • (+/-)-Methoxyverapamil
  • Ca channels,Calcium Channel,Inhibitor,inhibit,Verapamil,phenylalkylamine,antiarrhythmic,calcium,Gallopamil,vasodilator,Ca2+ channels
  • Zeatin Impurity 27
  • Benzeneacetonitrile, α-[3-[[2-(3,4-dimethoxyphenyl)ethyl]methylamino]propyl]-3,4,5-trimethoxy-α-(1-methylethyl)-
  • 16662-47-8
  • C28H41N2O5Cl
  • C28H40N2O5