ChemicalBook > CAS DataBase List > Taurohyodeoxycholic acid sodium salt hydrate

Taurohyodeoxycholic acid sodium salt hydrate

Product Name: Taurohyodeoxycholic acid sodium salt hydrate
CAS No.: 38411-85-7
Chemical Name: Taurohyodeoxycholic acid sodium salt hydrate
Synonyms: Taurine pig deoxycholate sodium;Sodium taurocholic acid deoxycholate;Taurohyodeoxycholic acid sodium salt hydrate;Taurohyodeoxycholic acid hydrate sodium salt;Taurohyodeoxycholic acid sodium salt, 10 mM in DMSO;5β-CHOLANIC ACID-3α, 6α-DIOL N-(2-SULPHOETHYL)-AMIDE;Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate
CBNumber: CB9547458
Molecular Formula: C26H46NNaO6S
Formula Weight: 523.7
MOL File: 38411-85-7.mol

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Taurohyodeoxycholic acid sodium salt hydrate Property

storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 20 mg/ml,Ethanol: 20 mg/ml
form: A crystalline solid
color: White to off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T0682
Product name: Sodium taurohyodeoxycholate hydrate
Purity: anionic
Packaging: 250mg
Price: $163.1
Updated: 2025/07/31

Sigma-Aldrich

Product number: T0682
Product name: Sodium taurohyodeoxycholate hydrate
Purity: anionic
Packaging: 1g
Price: $678
Updated: 2025/07/31

Cayman Chemical

Product number: 21956
Product name: Taurohyodeoxycholic Acid (sodium salt)
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 21956
Product name: Taurohyodeoxycholic Acid (sodium salt)
Packaging: 25mg
Price: $533
Updated: 2024/03/01

Cayman Chemical

Product number: 21956
Product name: Taurohyodeoxycholic Acid (sodium salt)
Packaging: 5mg
Price: $139
Updated: 2024/03/01

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Taurohyodeoxycholic acid sodium salt hydrate Chemical Properties,Usage,Production

Description

Taurohyodeoxycholic acid (THDCA) is a taurine-conjugated form of the secondary bile acid hyodeoxycholic acid . THDCA decreases the size and weight of human gallstones in vitro. It increases bile flow, biliary cholesterol secretion, and biliary lipid secretion in rats. Co-administration of THDCA with taurochenodeoxycholic acid (TCDCA; ) prevents TCDCA-induced hepatotoxicity, increasing bile flow as well as biliary acid and phospholipid secretion in rats. THDCA also reduces myeloperoxidase activity, expression of TNF-α and IL-6, and colonic damage in a mouse model of TNBS-induced ulcerative colitis.

Uses

Sodium taurohyodeoxycholate hydrate has been used in a study to assess dose-response data for cytotoxicity, regenerative cell proliferation and secondary oxidative DNA damage in rat livers treated with furan. It has also been used in a study to investigate the use of an immobilized artificial membrane HPLC column to predict bile salt-membrane interactions.

General Description

Sodium taurohyodeoxycholate hydrate is a taurine-amidated bile salt, which can be used as an anionic detergent.

References

[1] M ANGELICO. Dissolution of human cholesterol gallstones in bile salt/lecithin mixtures: effect of bile salt hydrophobicity and various pHs.[J]. Scandinavian Journal of Gastroenterology, 1995, 30 12: 1178-1185. DOI: 10.3109/00365529509101628
[2] M ANGELICO. Effect of taurohyodeoxycholic acid, a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.[J]. Digestive Diseases and Sciences, 1994, 39 11: 2389-2397. DOI: 10.1007/bf02087656
[3] ALDO RODA. Taurohyodeoxycholic acid protects against taurochenodeoxycholic acid–induced cholestasis in the rat[J]. Hepatology, 2003, 27 2: 520-525. DOI: 10.1002/hep.510270228
[4] JIAO HE . Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice[J]. European journal of pharmacology, 2011, 670 1: Pages 229-235. DOI: 10.1016/j.ejphar.2011.08.036

Taurohyodeoxycholic acid sodium salt hydrate Preparation Products And Raw materials

Raw materials

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View Lastest Price from Taurohyodeoxycholic acid sodium salt hydrate manufacturers

Shenzhen Nexcon Pharmatechs Ltd.

Product: Taurohyodeoxycholic acid sodium salt hydrate 38411-85-7
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 97%
Supply Ability: 2000
Release date: 2025-08-22

Anhuyan (Hainan) Biotechnology Co., LTD

Product: Taurohyodeoxycholic acid sodium salt hydrate 38411-85-7
Price: US $6.00/kg
Min. Order: 1kg
Purity: 99.99
Supply Ability: 100000
Release date: 2025-06-05

Career Henan Chemical Co

Product: Taurohyodeoxycholic acid sodium salt hydrate 38411-85-7
Price: US $1.00/g
Min. Order: 200KG
Purity: 99%
Supply Ability: 2tons
Release date: 2019-12-19

38411-85-7, Taurohyodeoxycholic acid sodium salt hydrateRelated Search:

Ursodeoxycholic acid Tauroursodeoxycholic acid GLYCODEOXYCHOLIC ACID SODIUM SALT ursodeoxycholate-3-sulfate GLYCOCHOLIC ACID SODIUM SALT Bisphenol A diphosphate Glycoursodeoxycholic Acid glycohyodeoxycholic acid GLYCODEOXYCHOLIC ACID TAUROCHENODEOXYCHOLIC ACID SODIUM SALT 2-[[(4R)-4-[(3R,5R,8R,9S,10S,13R,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonic acid 2-[4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoylamino]ethanesulfonic acid taurohyodeoxycholic acid TAUROCHOLIC ACID SODIUM SALT HYDRATE Sodium taurodeoxycholate hydrate TAUROHYODEOXYCHOLIC ACID SODIUM SALT Sodium taurocholate Taurodeoxycholic acid sodium salt

Taurohyodeoxycholic acid sodium salt hydrate

Taurohyodeoxycholic acid hydrate sodium salt

Sodium taurohyodeoxycholate hydrate,Taurohyodeoxycholic acid sodium salt hydrate

5β-CHOLANIC ACID-3α, 6α-DIOL N-(2-SULPHOETHYL)-AMIDE

Taurine pig deoxycholate sodium

Taurohyodeoxycholic acid sodium salt, 10 mM in DMSO

Sodium taurocholic acid deoxycholate

38411-85-7

C26H44NO6SNaxH2O