Methyl N-Boc-piperidine-3-carboxylate

Product Name: Methyl N-Boc-piperidine-3-carboxylate
CAS No.: 148763-41-1
Chemical Name: Methyl N-Boc-piperidine-3-carboxylate
Synonyms: METHYL N-BOC-NIPECOTATE;N-Boc- Piperidine-3-carboxylate;N-Boc-nipecotic acid methyl ester;Methyl N-Boc-piperidine-3-carboxylate;N-Boc-piperidine-3-carboxylate Methyl;TERT-BUTYL METHYL PIPERIDINE-1,3-DICARBOXYLATE;1-Boc-3-piperidinecarboxylic Acid Methyl Ester;N-Boc-3-piperidinecarboxylic acid methyl ester;N-Boc-piperidine-3-carboxylic acid Methyl ester;REF DUPL: Methyl N-Boc-piperidine-3-carboxylate
CBNumber: CB9679283
Molecular Formula: C12H21NO4
Formula Weight: 243.3
MOL File: 148763-41-1.mol

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Methyl N-Boc-piperidine-3-carboxylate Property

Melting point:: 47.0 to 51.0 °C
Boiling point:: 307.4±35.0 °C(Predicted)
Density: 1.094±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: powder to crystal
pka: -2.48±0.40(Predicted)
color: White to Light yellow
InChI: InChI=1S/C12H21NO4/c1-12(2,3)17-11(15)13-7-5-6-9(8-13)10(14)16-4/h9H,5-8H2,1-4H3
InChIKey: LYYJQMCPEHXOEW-UHFFFAOYSA-N
SMILES: N1(C(OC(C)(C)C)=O)CCCC(C(OC)=O)C1

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Safety

Risk Statements: 36/37/38
Safety Statements: 26-36
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TCI Chemical

Product number: M2918
Product name: Methyl 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylate
Purity: >98.0%(GC)
Packaging: 5g
Price: $27
Updated: 2025/07/31

TCI Chemical

Product number: M2918
Product name: Methyl 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylate
Purity: >98.0%(GC)
Packaging: 25g
Price: $96
Updated: 2025/07/31

TRC

Product number: M294473
Product name: MethylN-Boc-piperidine-3-carboxylate
Packaging: 500mg
Price: $65
Updated: 2021/12/16

TRC

Product number: M294473
Product name: MethylN-Boc-piperidine-3-carboxylate
Packaging: 100mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 455957
Product name: Methyl N-Boc-piperidine-3-carboxylate
Packaging: 100mg
Price: $305
Updated: 2021/12/16

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Methyl N-Boc-piperidine-3-carboxylate Chemical Properties,Usage,Production

Chemical Properties

White solid

Synthesis

71381-75-4

18107-18-1

148763-41-1

Trimethylsilylated diazomethane (14.18 ml, 2.0 M, 28.35 mmol) was added slowly and dropwise to a 20% methanol/toluene (100 ml) solution of 1-BOC-piperidine-3-carboxylic acid (5.00 g, 21.81 mmol) at room temperature. The reaction was monitored by thin layer chromatography (TLC) until the reaction was completed. After completion of the reaction, the reaction mixture was concentrated under reduced pressure to afford methyl N-Boc-3-piperidinecarboxylate (Intermediate 53) 4.44 g in 83.7% yield. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δppm 1.4 (s, 9H), 1.6 (d, J = 3.4 Hz, 1H), 1.6 (m, 1H), 1.7 (m, 1H), 2.0 (m, 1H), 2.4 (m, 1H), 2.8 (m, 1H), 3.0 (s, 1H), 3.7 (s, 3H) , 3.9 (d, J13.2 Hz, 1H), 4.1 (s, 1H).

References

[1] Patent: US2006/116376, 2006, A1. Location in patent: Page/Page column 16
[2] Patent: WO2011/141728, 2011, A1. Location in patent: Page/Page column 19-20

Methyl N-Boc-piperidine-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyl N-Boc-piperidine-3-carboxylate Suppliers

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View Lastest Price from Methyl N-Boc-piperidine-3-carboxylate manufacturers

Wuhan Xinhao Biotechnology Co., Ltd

Product: Methyl N-Boc-piperidine-3-carboxylate 148763-41-1
Price: US $10.00-100.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 Metric Ton/Month
Release date: 2024-03-12

Anhui Zhongda Biotechnology Co., Ltd

Product: Methyl N-Boc-piperidine-3-carboxylate 148763-41-1
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100tons
Release date: 2023-10-26

Jinan Ande Pharmaceutical Co.,Ltd.

Product: Methyl N-Boc-piperidine-3-carboxylate 148763-41-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1000
Release date: 2021-12-20

148763-41-1, Methyl N-Boc-piperidine-3-carboxylateRelated Search:

Methyl acetate Methyl formate Methyl anthranilate Methyl 4-cyanobenzoate Methyl benzoate N-Boc-Piperidine-4-carboxylic acid methyl ester Kresoxim-methyl RESMETHRIN Methylparaben Nipecotic acid Methyl isonipecotate Tribenuron methyl METSULFURON METHYL Methyl carbamate Methyl salicylate Methyl acrylate Thiophanate-methyl Methyl

TERT-BUTYL METHYL PIPERIDINE-1,3-DICARBOXYLATE

METHYL N-BOC-NIPECOTATE

piperidine-1,3-dicarboxylic acid O1-tert-butyl ester O3-methyl ester

Methyl 1-(tert-butoxycarbonyl)-3-piperidinedicarboxylate

1-TERT-BUTYL 3-METHYL PIPERIDINE-1,3-DICARBOXYLATE

N-Boc-nipecotic acid methyl ester

N-Boc- Piperidine-3-carboxylate

Methyl N-Boc-piperidine-3-carboxylate

REF DUPL: Methyl N-Boc-piperidine-3-carboxylate

N-Boc-piperidine-3-carboxylate Methyl

N-Boc-piperidine-3-carboxylic acid Methyl ester

1-[(tert-butoxy)carbonyl]-2-Methylpiperidine-3-carboxylate

1,3-Piperidinedicarboxylic acid, 1-(1,1-diMethylethyl) 3-Methyl ester

N-Boc-Piperidine-3-carboxylate or 1-N-BOC-3-piperidinecarboxylic acid Methyl ester

Methyl 1-(tert-Butoxycarbonyl)-3-piperidinecarboxylate

1-(tert-Butoxycarbonyl)-3-piperidinecarboxylic Acid Methyl Ester

1-Boc-3-piperidinecarboxylic Acid Methyl Ester

Piperidine-1,3-dicarboxylic Acid 1-tert-Butyl 3-Methyl

1-(1,1-Dimethylethyl) 3-methyl 1,3-piperidinedicarboxylate

N-Boc-3-piperidinecarboxylic acid methyl ester

1-(tert-Butyl) 3-methyl 1,3-piperidinedicarboxylate

148763-41-1

63-41-1