ChemicalBook > CAS DataBase List > tert-Butyl carbazate

tert-Butyl carbazate

Product Name
tert-Butyl carbazate
CAS No.
870-46-2
Chemical Name
tert-Butyl carbazate
Synonyms
tert-butyl hydrazinecarboxylate;carbazate;BOC-NHNH2;BOC-HYDRAZINE;T-BUTYLCARBAZATE;tert-Butyl N-aminocarbamate;HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER;BOC-HYDRAZIDE;TERT-BUTOXYCARBONYL HYDRAZIDE;T-BOC-HYDRAZIDE
CBNumber
CB9686391
Molecular Formula
C5H12N2O2
Formula Weight
132.16
MOL File
870-46-2.mol
More
Less

tert-Butyl carbazate Property

Melting point:
39-42 °C (lit.)
Boiling point:
63-65 °C/0.1 mmHg (lit.)
Density 
1.02
refractive index 
1.4496 (estimate)
Flash point:
197 °F
storage temp. 
Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility 
Soluble in ethanol and methanol.
pka
10.74±0.20(Predicted)
form 
Crystalline Lumps
color 
White to slightly yellow
Sensitive 
Moisture Sensitive
BRN 
1756967
InChIKey
DKACXUFSLUYRFU-UHFFFAOYSA-N
CAS DataBase Reference
870-46-2(CAS DataBase Reference)
EPA Substance Registry System
Hydrazinecarboxylic acid, 1,1-dimethylethyl ester (870-46-2)
More
Less

Safety

Hazard Codes 
T-F,T,F
Risk Statements 
48-36/37/38-24/25-11
Safety Statements 
45-36/37/39-16-24/25
RIDADR 
1325
WGK Germany 
3
F 
21
TSCA 
Yes
HazardClass 
4.1
PackingGroup 
III
HS Code 
29280090
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H228Flammable solid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B91005
Product name
tert-Butyl carbazate
Purity
98%
Packaging
5g
Price
$38.5
Updated
2024/03/01
Sigma-Aldrich
Product number
B91005
Product name
tert-Butyl carbazate
Purity
98%
Packaging
25g
Price
$79.4
Updated
2024/03/01
Alfa Aesar
Product number
A12383
Product name
tert-Butyl carbazate, 98+%
Packaging
25g
Price
$74.2
Updated
2024/03/01
Alfa Aesar
Product number
A12383
Product name
tert-Butyl carbazate, 98+%
Packaging
100g
Price
$126.65
Updated
2024/03/01
Sigma-Aldrich
Product number
B91005
Product name
tert-Butyl carbazate
Purity
98%
Packaging
100g
Price
$148
Updated
2024/03/01
More
Less

tert-Butyl carbazate Chemical Properties,Usage,Production

Chemical Properties

White to pale yellow lumps

Uses

Starting material for preparing BOC-azide, a reagent to introduce the BOC amino protection.

Uses

tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.

Synthesis Reference(s)

Journal of the American Chemical Society, 82, p. 2725, 1960 DOI: 10.1021/ja01496a018
Chemical and Pharmaceutical Bulletin, 18, p. 217, 1970 DOI: 10.1248/cpb.18.217

Purification Methods

Distil it in a Claisen flask with a water or oil bath at ca 80o. After a couple of drops have distilled, the carbazate is collected as an oil which solidifies to a snow white solid. It can be crystallised with 90% recovery from a 1:1 mixture of pet ether (b 30-60o) and pet ether (b 60-70o). [Carpino et al. Org Synth Coll Vol V 166 1973, Caprino et al. Org Synth 44 20 1964, Beilstein 3 IV 175.]

tert-Butyl carbazate Preparation Products And Raw materials

Raw materials

Hydrazinium hydroxide solution Di-tert-butyl dicarbonate Hydrazine hydrate Isopropyl alcohol

Preparation Products

PYRIDIN-2-YLMETHYL-HYDRAZINE PYRIDIN-3-YLMETHYL-HYDRAZINE (2-METHOXY-1-METHYL-ETHYL)-HYDRAZINE PYRIDIN-4-YLMETHYL-HYDRAZINE CYCLOBUTYLHYDRAZINE 3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
More
Less

tert-Butyl carbazate Suppliers

Australia 1 Belgium 4 Canada 2 China 451 Europe 1 France 2 Germany 14 India 72 Japan 8 Spain 1 Sweden 2 Switzerland 3 The Netherlands 1 United Kingdom 14 United States 52 Global 628
BTC pharm India
Tel
+918790379245
Email
banny.janga@btcpharm.com
Country
India
ProdList
1262
Advantage
58
GLR Innovations
Tel
+91 9891111994
Email
info@glrgroup.in
Country
India
ProdList
4535
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Gm-chemsys
Tel
--
Fax
--
Email
ctgmchemsys1@gmail.com
Country
India
ProdList
42
Advantage
50
Survival Technologies Pvt Ltd
Tel
--
Fax
--
Email
swami@survivaltechnologies.in
Country
India
ProdList
290
Advantage
50
A. B. Enterprises
Tel
--
Fax
--
Email
mlbang@rediffmail.com
Country
India
ProdList
1394
Advantage
58
Triveni chemicals
Tel
--
Fax
--
Email
sales@trivenichemical.com
Country
India
ProdList
6088
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
Sisco Research Laboratories Pvt. Ltd.
Tel
--
Fax
--
Email
marketing@srlchem.com
Country
India
ProdList
4315
Advantage
58
Sisco Resech Laboratories Private Limited
Tel
--
Fax
--
Country
India
ProdList
655
Advantage
58
Jay Chemicals
Tel
--
Fax
--
Country
India
ProdList
67
Advantage
58
Tosco Pharmachem Pvt Ltd.
Tel
--
Fax
--
Email
response@toscopharmachem.com
Country
India
ProdList
37
Advantage
58
Innovative Labs
Tel
--
Fax
--
Email
info@innovativelabsindia.com
Country
India
ProdList
110
Advantage
58
Vasista Pharma Chem Pvt., Ltd. (Vasista Group)
Tel
--
Fax
--
Email
srinivasaraju@vasista.co.in
Country
India
ProdList
34
Advantage
58
Vedanta Biosciences
Tel
--
Fax
--
Email
info@vedantabio.co.in
Country
India
ProdList
25
Advantage
58
HiMedia Laboratories
Tel
--
Fax
--
Email
o@himedialabs.com
Country
India
ProdList
1841
Advantage
58
Azole Rasayanas India Private Limited
Tel
--
Fax
--
Email
info@azolerasayanas.com
Country
India
ProdList
681
Advantage
58
HONOUR LAB LIMITED
Tel
--
Fax
--
Email
info@honourlab.com
Country
India
ProdList
67
Advantage
58
Sanpra Synthesis Pvt., Ltd.
Tel
--
Fax
--
Email
info@sanpra.in
Country
India
ProdList
27
Advantage
58
Dhanvi Exim Services
Tel
--
Fax
--
Email
info@dhanviexim.com
Country
India
ProdList
204
Advantage
58
Survival Technologies Pvt., Ltd. (STPL)
Tel
--
Fax
--
Email
info@survivaltechnologies.in
Country
India
ProdList
119
Advantage
58
S. Amit Speciality Chemicals Pvt. Ltd.
Tel
--
Fax
--
Email
gupta@s-amit.com
Country
India
ProdList
177
Advantage
58
Anand Agencies
Tel
--
Fax
--
Email
en@gmail.com
Country
India
ProdList
2332
Advantage
58
Dr. R.R. Organics
Tel
--
Fax
--
Email
drrrorg20@gmail.com
Country
India
ProdList
200
Advantage
58
Asiel Chempharma
Tel
--
Fax
--
Email
asielchempharma@gmail.com
Country
India
ProdList
119
Advantage
58
Dr. Silviu Pharmachem Pvt., Ltd. (DRSPL)
Tel
--
Fax
--
Email
info@drspl.in
Country
India
ProdList
143
Advantage
58
Jay Chem Marketing
Tel
--
Fax
--
Country
India
ProdList
231
Advantage
58
Amino Organics
Tel
--
Fax
--
Country
India
ProdList
86
Advantage
58
GMFC Labs Pvt. Ltd.
Tel
--
Fax
--
Email
vasu@gmfclabs.com
Country
India
ProdList
23
Advantage
58
Survival Technologies Private Limited
Tel
--
Fax
--
Country
India
ProdList
153
Advantage
58
VASIN BIO LIFE SCIENCES PVT LTD
Tel
--
Fax
--
Email
info@vasinbio.com
Country
India
ProdList
2092
Advantage
58
S.Zhaveri Pharmakem Pvt. Ltd
Tel
--
Fax
--
Country
India
ProdList
58
Advantage
58
RVR Labs Private Limited
Tel
--
Fax
--
Country
India
ProdList
49
Advantage
58
Global Chemie
Tel
--
Fax
--
Country
India
ProdList
162
Advantage
58
Reax Chemicals
Tel
--
Fax
--
Country
India
ProdList
4217
Advantage
58
ASM Organics
Tel
--
Fax
--
Country
India
ProdList
1185
Advantage
58
Spectrochem Private Limited
Tel
--
Fax
--
Country
India
ProdList
1055
Advantage
58
Snap Intermediates
Tel
--
Fax
--
Country
India
ProdList
110
Advantage
58
Drug Mart Intermediates And Chemicals
Tel
--
Fax
--
Country
India
ProdList
56
Advantage
58
GM Fine Chemicals
Tel
--
Fax
--
Country
India
ProdList
15
Advantage
58
Sagar Life Sciences Pvt. Ltd.
Tel
--
Fax
--
Country
India
ProdList
54
Advantage
58
Clayden Organics
Tel
--
Fax
--
Country
India
ProdList
31
Advantage
58
Central Drug House(P) Ltd.
Tel
--
Fax
--
Email
sales@cdhfinechemical.com
Country
India
ProdList
6157
Advantage
58
A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
More
Less

View Lastest Price from tert-Butyl carbazate manufacturers

hebei hongtan Biotechnology Co., Ltd
Product
Tert-Butyl carbazate 870-46-2
Price
US $30.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000kg
Release date
2024-05-13
Hebei Longbang Technology Co., Ltd
Product
tert-Butyl carbazate 870-46-2
Price
US $6.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20TONS
Release date
2024-06-03
Hebei Weibang Biotechnology Co., Ltd
Product
tert-Butyl carbazate 870-46-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-01

870-46-2, tert-Butyl carbazateRelated Search:

butyl rubber Buprofezin Methyl 4-tert-butylbenzoate Di-tert-butyl dicarbonate Butyl benzoate tert-Butyldimethylsilyl chloride tert-Butanol TEREPHTHALIC DIHYDRAZIDE tert-Butyl methyl ether Di-tert-butyl peroxide 4-tert-Butylphenol Cyhalofop-butyl Isobutyl chloroformate Butyl methacrylate 4-tert-Butylcatechol Diisobutyl phthalate tert-Butyl acetate tert-Butyl peroxybenzoate

  • TERT-BUTOXYCARBONYL HYDRAZIDE
  • TERT-BUTOXYCARBONYLHYDRAZINE
  • TERT-BOC-HYDRAZIDE
  • TERT-BUTYLOXYCARBAZATE
  • tert-butyloxycarbonyl-hydrazide
  • T-BOC-HYDRAZIDE
  • T-BUTOXYCARBONYL HYDRAZIDE
  • T-BUTYLCARBAZATE
  • T-BUTYLOXYCARBONYL-HYDRAZIDE
  • tert-Butyl hydrazinocarboxylate
  • tert-Butylcarbazate,98+%
  • BOC-HYDRAZIDE 98%
  • TERT-BUTYL CARBAZATE 99%
  • tert-Butyl carbazate, 97+%
  • tert-Butoxycarbonyl hydrazide, Boc-hydrazide
  • tert-Butyl N-aminocarbamate
  • N-T-BUTOXYCARBONYL-HYDRAZIDE
  • CustoM-Made product
  • tert-Butyl carbaza
  • tert-butyl hydrazinecarboxylate
  • 1-Boc hydrazine
  • <i>tert</i>-Butyl carbazate
  • Hydrazinecarboxylic acid-1,1-dimethyl ester
  • BOC-Hydrazine tert-Butyl carbazate
  • Tert-Cutyl Carbazate
  • tert-Butyl hydrazinoformate
  • Boc-hydrazide≥ 99% (GC)
  • Carbazic acid 1,1-dimethylethyl ester
  • N-Aminocarbamic acid tert-butyl ester
  • tert-Butyl carbazate,99%
  • LABOTEST-BB LT00053500
  • Boc-hydrazine tert-Butoxycarbonylhydrazine Carbazic Acid tert-Butyl Ester
  • TERT-BUTYL CARBAZATE FOR SYNTHESIS
  • hydrazinecarboxylicacid,1,1-dimethylethylester
  • AKOS B028820
  • Tert-Butyl carbazateCAS
  • BOC-hydrazide（Tert-Butyl carbazate）
  • tert-Butyl carbazate,tert-Butoxycarbonyl hydrazide, Boc-hydrazide
  • tert-Butyl carbazate
  • tert-Butyl carbazate, 99% 100GR
  • tert-Butyl carbazate, 99% 500GR
  • HYDRAZINECARBOXYLIC ACID TERT-BUTYL ESTER
  • +-BUTYL CARBAZATE
  • CARBONIC ACID TERT-BUTYL ESTER HYDRAZIDE
  • CARBAZINIC ACID TERT-BUTYL ESTER
  • CARBAZIC ACID TERT-BUTYL ESTER
  • BOC-HYDRAZIDE
  • BOC-HYDRAZINE
  • BOC-NHNH2
  • Baloxavir Impurity 35
  • ert-Butyl carbazate
  • tert-Butyl carbazate T-BOC-HYDRAZIDE
  • tert-Butyl carbazate solution
  • carbazate
  • tert-Butyl Carbazate &gt
  • tert-Butyl carbazate, 99%, for synthesis
  • N-BOC-HYDRAZINE
  • 1-Boc hydrazine(BOC-NHNH2)