Pentafluoro-1-propanol

Product Name: Pentafluoro-1-propanol
CAS No.: 422-05-9
Chemical Name: Pentafluoro-1-propanol
Synonyms: 2,2,3,3,3-PENTAFLUOROPROPAN-1-OL;2,2,3,3,3-PENTAFLUORO-1-PROPANOL;PFPOH;C2F5CH2OH;PENTAFLUOROPROPANOL;PENTAFLUORO-1-PROPANOL;1,1H-perfluoropropanol;1H,1H-Perfluoropropanol;Pentafluoropropylalcohol;PERFLUORODIHYDROPROPANOL
CBNumber: CB9689963
Molecular Formula: C3H3F5O
Formula Weight: 150.05
MOL File: 422-05-9.mol

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Pentafluoro-1-propanol Property

Boiling point:: 80 °C748 mm Hg(lit.)
Density: 1.505 g/mL at 25 °C(lit.)
vapor pressure: 62.055-324.857hPa at 24.93-54.78℃
refractive index: n20/D 1.288(lit.)
Flash point:: 80-81°C
storage temp.: Flammables area
pka: 12.45±0.10(Predicted)
form: Powder, Crystals and/or Chunks
Specific Gravity: 1.509
color: White to off-white to light yellow
Water Solubility: Soluble in water.21.9 g/L at 25°C
BRN: 1743133
InChIKey: PSQZJKGXDGNDFP-UHFFFAOYSA-N
LogP: 1.23
CAS DataBase Reference: 422-05-9(CAS DataBase Reference)
NIST Chemistry Reference: 2,2,3,3,3-Pentafluoro-1-propanol(422-05-9)
EPA Substance Registry System: 1-Propanol, 2,2,3,3,3-pentafluoro- (422-05-9)

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Safety

Hazard Codes: Xn,Xi
Risk Statements: 22-36/37/38-20-10
Safety Statements: 26-36-36/37/39-16
RIDADR: 1987
WGK Germany: 3
RTECS: UB8800000
TSCA: T
HazardClass: IRRITANT
HS Code: 29055900
Toxicity: LDLo orl-rat: 2250 mg/kg JOCMA7 4,262,62

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 257478
Product name: 2,2,3,3,3-Pentafluoro-1-propanol
Purity: 97%
Packaging: 5g
Price: $43
Updated: 2025/07/31

Sigma-Aldrich

Product number: 257478
Product name: 2,2,3,3,3-Pentafluoro-1-propanol
Purity: 97%
Packaging: 25g
Price: $134
Updated: 2025/07/31

TCI Chemical

Product number: P0845
Product name: 2,2,3,3,3-Pentafluoro-1-propanol
Purity: >98.0%(GC)
Packaging: 25g
Price: $102
Updated: 2025/07/31

Sigma-Aldrich

Product number: 79879
Product name: 2,2,3,3,3-Pentafluoro-1-propanol
Purity: for GC derivatization, ≥98.5% (GC)
Packaging: 10ml
Price: $236
Updated: 2025/07/31

Sigma-Aldrich

Product number: 257478
Product name: 2,2,3,3,3-Pentafluoro-1-propanol
Purity: 97%
Packaging: 250g
Price: $623.7
Updated: 2025/07/31

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Pentafluoro-1-propanol Chemical Properties,Usage,Production

Chemical Properties

clear colorless to slightly yellow liquid

Uses

2,2,3,3,3-Pentafluoro-1-Propanol is a useful reagent for the preparation of (oxoindolinyl)ethers/benzoates via photochemical O-H functionalization reactions of cyclic diazoamides.

Uses

2,2,3,3,3-Pentafluoro-1-propanol has been used:

as derivatization reagent in detection of unlabeled and ¹⁵N₂ -labeled L-tryptophan, L-kynurenine, serotonin and quinolinic acid in human and rat plasma by GC-MS
as derivatization reagent in simultaneous analysis of cocaine, cocaethylene and their possible metabolic and pyrolytic products in blood, urine and muscle by GC-MS
preparation of trifluoromethyl ynamines which, in turn, converted aldehydes to α-trifluoromethyl-α,β-unsaturated amides
to generate fluorinated α-keto ethers with alkenes and has wide applications in the expanding fluorous research area

General Description

2,2,3,3,3-Pentafluoro-1-propanol is an alternative cleaning agent for chlorofluorocarbon.

reaction suitability

reagent type: derivatization reagent
reaction type: Acylations

Safety Profile

Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of Fí.

Purification Methods

Shake the alcohol with alumina for 24hours, dry with anhydrous K2CO3, and distil it, collect the middle fraction (b 80-81o) and redistil it. [Beilstein 1 IV 1438.]

Pentafluoro-1-propanol Preparation Products And Raw materials

Raw materials

Preparation Products

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Pentafluoro-1-propanol Suppliers

Americas 1 Belgium 1 Canada 2 CHINA 160 Europe 2 France 1 Germany 6 India 6 Japan 10 Poland 1 Russia 1 Slovakia 1 Spain 1 Switzerland 2 The Netherlands 1 Ukraine 1 United Kingdom 12 United States 42 Global 251

J & K SCIENTIFIC LTD.

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INTATRADE GmbH

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Jia Xing Isenchem Co.,Ltd

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Pure Chemistry Scientific Inc.

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View Lastest Price from Pentafluoro-1-propanol manufacturers

Career Henan Chemical Co

Product: 2,2,3,3,3-Pentafluoro-1-Propanol 422-05-9
Price: US $250.00/KG
Min. Order: 2KG
Purity: 98%
Supply Ability: 500kg per month
Release date: 2018-07-24

422-05-9, Pentafluoro-1-propanolRelated Search:

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2，2，3，3，3-Pentafluoropropanol-1

1H,1H-PENTAFLUOROPROPANOL 97%

2,2,3,3,3-Pentafluoropropan-1-ol 98%

2,2,3,3,3-Pentafluoropropan-1-ol98%

2,2,3,3,3-Pentafluoropropanol (PFP)

2,2,3,3,3-PENTAFLUORO-L-PROPANOL

2,2,3,3,3-PENTAFLUORO-1-PROPANOL

2,2,3,3,3-PENTAFLUOROPROPAN-1-OL

2,2,3,3,3-PENTAFLUOROPROPANOL

2,2,3,3,3-Pentafluoro-1-propanol, 95+%

Pentafluoropropylalcohol

2,2,3,3,3-Pentafluoro-1-propanol,97%

1H,1H-Pentafluoropropan-1-ol

3-Hydroxy-1,1,1,2,2-pentafluoropropane, 1H,1H-Pentafluoropropan-1-ol

PFPOH

PENTAFLUOROPROPANOL

PERFLUORODIHYDROPROPANOL

PENTAFLUORO-1-PROPANOL

1,1-Dihydroperfluoropropanol

1,1H-perfluoropropanol

1-Propanol, 2,2,3,3,3-pentafluoro-

2,2,3,3,3-pentafluoro-1-propano

C2F5CH2OH

propanol,2,2,3,3,3-pentafluoro-

Pentafluoropropionic alcohol

1H,1H-PENTAFLUORO-1-PROPANOL

1H,1H-PENTAFLUOROPROPANOL

1H,1H-PENTAFLUOROPROPANOL-1

2,2,3,3,3-Pentafluoro-1-propanol&gt

2,2,3,3,3-Pentafluoropropan-1-ol in methanol

1H,1H-Perfluoropropanol

1H,1H-Perfluoropropanol in Methanol

2,2,3,3,3-Pentafluoro-1-propanol, 98%

2,2,3,3,3-Pentafluoropropan-1-ol, 100 μg/mL PT Methanol

422-05-9

CF3CF2CH2OH

C3H3OF5

Organic Building Blocks

Oxygen Compounds

C2 to C6

Building Blocks

Alkylation

Alcohols

ALCOHOL

Acylation Reagent