Perfluoropropionic acid
- Product Name
- Perfluoropropionic acid
- CAS No.
- 422-64-0
- Chemical Name
- Perfluoropropionic acid
- Synonyms
- PENTAFLUOROPROPIONIC ACID;2,2,3,3,3-Pentafluoropropanoic acid;PERFLUOROPROPANOIC ACID;Pentafluoropropanoic acid;Pentafluoropropionic acid (PFPA);2,2,3,3,3-PENTAFLUOROPROPIONIC ACID;IPC-PFFA-3;uoropropionic Acid;RARECHEM AL BO 0422;Pentafluorpropionsure
- CBNumber
- CB6139447
- Molecular Formula
- C3HF5O2
- Formula Weight
- 164.03
- MOL File
- 422-64-0.mol
Perfluoropropionic acid Property
- Boiling point:
- 96-97 °C (lit.)
- Density
- 1.561 g/mL at 25 °C (lit.)
- vapor density
- ~5.6 (vs air)
- vapor pressure
- ~40 mm Hg ( 20 °C)
- refractive index
- n20/D 1.284(lit.)
- Flash point:
- None
- storage temp.
- Store below +30°C.
- Water Solubility
- Soluble in water
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- pka
- 0.38±0.10(Predicted)
- form
- Liquid
- color
- Clear colorless to slightly brown
- Specific Gravity
- 1.561
- Sensitive
- Hygroscopic
- BRN
- 1773387
- Stability:
- hygroscopic
- Major Application
- PFAS testing
- InChI
- 1S/C3HF5O2/c4-2(5,1(9)10)3(6,7)8/h(H,9,10)
- InChIKey
- LRMSQVBRUNSOJL-UHFFFAOYSA-N
- SMILES
- OC(=O)C(F)(F)C(F)(F)F
- CAS DataBase Reference
- 422-64-0(CAS DataBase Reference)
- NIST Chemistry Reference
- Pentafluoropropionic acid(422-64-0)
- EPA Substance Registry System
- Pentafluoropropionic acid (422-64-0)
Safety
- Hazard Codes
- C
- Risk Statements
- 20-34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3265 8/PG 2
- WGK Germany
- 3
- RTECS
- UF6475000
- F
- 3
- Hazard Note
- Corrosive
- TSCA
- TSCA listed
- HazardClass
- 8
- PackingGroup
- III
- HS Code
- 29159080
- Storage Class
- 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects - Hazard Classifications
- Acute Tox. 3 Inhalation
Eye Dam. 1
Met. Corr. 1
Skin Corr. 1B - Toxicity
- LD10 orl-rat: 750 mg/kg GTPZAB10(3),13,66
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H290May be corrosive to metals
H314Causes severe skin burns and eye damage
H331Toxic if inhaled
- Precautionary statements
-
P234Keep only in original container.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.20956
- Product name
- 2,2,3,3,3-Pentafluoropropionic acid
- Purity
- for synthesis
- Packaging
- 10ml
- Price
- $67.8
- Updated
- 2025/07/31
- Product number
- 8.20956
- Product name
- 2,2,3,3,3-Pentafluoropropionic acid
- Purity
- for synthesis
- Packaging
- 50mL
- Price
- $271
- Updated
- 2025/07/31
- Product number
- 245917
- Product name
- Pentafluoropropionic acid
- Purity
- 97%
- Packaging
- 10g
- Price
- $55.7
- Updated
- 2025/07/31
- Product number
- 245917
- Product name
- Pentafluoropropionic acid
- Purity
- 97%
- Packaging
- 50g
- Price
- $200
- Updated
- 2025/07/31
- Product number
- P1125
- Product name
- Pentafluoropropionic Acid
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $136
- Updated
- 2025/07/31
Perfluoropropionic acid Chemical Properties,Usage,Production
Chemical Properties
Perfluoropropionic acid (PFPrA[2]) or pentafluoropropionic acid is the perfluoroalkyl carboxylic acid with the formula CF3CF2CO2H. It is a clear colourless to slightly brown liquid that is strongly acidic and soluble in water and polar organic solvents.
Uses
Pentafluoropropionic acid is used as an efficient catalyst for the preparation of dibenzo[a, j] xanthenes by condensation reaction of beta-naphthol with aryl aldehydes.
Uses
Pentafluoropropionic acid (Perfluoropropionic acid) was used in the analysis of gentamicin with Gemini column by liquid chromatographic (LC) methods.
General Description
The kinetics of the reaction of pentafluoropropionic acid with fluorine atoms was studied.
Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion.When heated to decomposition it emits toxic fumes of Fí.
Synthesis
A cogeneration process of hexafluoroisopropyl methyl ether and pentafluoropropionic acid:
(1) weighing 32 g of methanol in a 250 mL round-bottomed flask, to which 8.1 g of sodium methanol was added and stirred until it was fully dissolved, to obtain a methanol solution of sodium methanol;
(2) weighing 31.6 g of perfluoro-2-methyl-2,3-epoxypentane in the methanol solution of sodium methanol from step 1), sealing the Round bottom flask, it will be placed in a cold bath at 0 , 700r/min stirring reaction for 2h, to get the product containing the mixture;
(3) the product of step 2) will be filtered to remove insoluble salts, to the filtrate to add deionized water to wash three times to remove methanol, aqueous wash solution after fractionation to take the lower layer of the liquid distillation, the purity of 99.5% of the hexafluoroisopropyl methyl ether and pentafluoropropionic acid Methyl pentafluoropropionate;
(4) add 400mL of sulfuric acid with a concentration of 1 mol/L to methyl pentafluoropropionate, stirring at 60C for 3h, and distillate at the end of the reaction to obtain pentafluoropropionic acid with a purity of 99%.
This hexafluoroisopropyl methyl ether cogeneration process of pentafluoropropionic acid adopts methoxy alkali metal salt and perfluoro-2-methyl-2,3-epoxypentane as the main raw materials, and carries out ring-opening alkylation reaction under the condition of alcohol solvent to obtain hexafluoroisopropyl methyl ether and pentafluoropropionic acid at the same time, and avoids the problems of hexafluoroisopropanol as raw materials in the existing technology which is expensive, and dimethyl sulphate is a highly toxic alkylation reagent, and its The process route is simple, and both the main product and by-product have economic value, which is suitable for industrial application.
Perfluoropropionic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Perfluoropropionic acid manufacturers
- Product
- Pentafluoropropanoic acid 422-64-0
- Price
- US $2.20-8.80/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-24
- Product
- Perfluoropropionic acid 422-64-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-08
- Product
- Perfluoropropionic acid 422-64-0
- Price
- US $0.10/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000 tons
- Release date
- 2020-01-03