ChemicalBook > CAS DataBase List > 2-Bromopropionic acid

2-Bromopropionic acid

Product Name
2-Bromopropionic acid
CAS No.
598-72-1
Chemical Name
2-Bromopropionic acid
Synonyms
2-BROMOPROPANAMIDE;(S)-2-BROMOPROPANOIC ACID;A-BROMOPROPIONIC ACID;ALPHA-BROMOPROPIONIC ACID;2-broMide;3-(3-(4'2-Bromopropion;-Bromo-[1,1'DL-2-Bromopropionic;RARECHEM AL BO 1266
CBNumber
CB2260767
Molecular Formula
C3H5BrO2
Formula Weight
152.97
MOL File
598-72-1.mol
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2-Bromopropionic acid Property

Melting point:
25.7°C
Boiling point:
203 °C (lit.)
Density 
1.7 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.475(lit.)
Flash point:
212 °F
storage temp. 
room temp
form 
Liquid After Melting
pka
pK1: 2.971 (25°C)
Specific Gravity
1.7
color 
Clear colorless to yellow
Water Solubility 
soluble
BRN 
605451
Dielectric constant
11.0
NIST Chemistry Reference
2-Bromopropanoic acid(598-72-1)
EPA Substance Registry System
Propanoic acid, 2-bromo- (598-72-1)
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Safety

Hazard Codes 
C,Xi,F
Risk Statements 
22-34-40-36/37/38-38-11
Safety Statements 
26-36/37/39-45-36-16-24-9
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
RTECS 
UA2451715
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29159080
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B78300
Product name
2-Bromopropionic acid
Purity
99%
Packaging
1kg
Price
$217
Updated
2024/03/01
Sigma-Aldrich
Product number
47645
Product name
2-Bromopropionic acid solution
Purity
certified reference material, 1000?μg/mL in methyl tert-butyl ether
Packaging
1mL
Price
$37.2
Updated
2022/05/15
TCI Chemical
Product number
B0644
Product name
2-Bromopropionic Acid
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$20
Updated
2024/03/01
TCI Chemical
Product number
B0644
Product name
2-Bromopropionic Acid
Purity
>98.0%(GC)(T)
Packaging
500g
Price
$73
Updated
2024/03/01
Alfa Aesar
Product number
A17569
Product name
2-Bromopropionic acid, 98%
Packaging
250g
Price
$66
Updated
2024/03/01
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2-Bromopropionic acid Chemical Properties,Usage,Production

Chemical Properties

clear colorless to yellowish liquid after melting. soluble in water, miscible with alcohol, ether, chloroform and benzene.

Uses

It is employed as pharmaceutical and agrochemical intermediate. It is used as an alkylation agent for mercaptans and other sulfur containing compounds.

Uses

2-Bromopropionic Acid is a versatile reactant used in emulsion polymerization in the preparation of reversible addition-fragmentation chain transfer (RAFT) agent.

Application

2-bromopropionic acid is an organic synthesis intermediate, used in the production of herbicides quizalofop-ethyl, napropamide, fenthiaprop and fungicides metalaxyl, benalaxyl, procymidone, etc., used in the synthesis of pharmaceutical intermediates body alanine.

Preparation

2-Bromopropionic acid is obtained by bromination of propionic acid. Add propionic acid and phosphorus trichloride to the reaction kettle, keep the temperature at 80°C, slowly add bromine to the reaction solution dropwise, and heat up to 85°C after the addition of bromine, and raise the temperature to 100°C when the color of bromine disappears completely, it takes about 2~3h, and then the bromine and hydrobromic acid are recovered under reduced pressure, and then the finished product is obtained by distillation under reduced pressure.

Synthesis Reference(s)

Tetrahedron Letters, 13, p. 4067, 1972 DOI: 10.1016/S0040-4039(01)94239-X

2-Bromopropionic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Bromopropionic acid Suppliers

Wuhan Hongde Yuexin Pharmaceutical Technology Co., Ltd
Tel
02783850058 15377551550
Fax
027-83850058
Email
whhdyxchem027@sina.com
Country
China
ProdList
3074
Advantage
58
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TAIYUAN RHF CO.,LTD.
Tel
+86 351 7031519
Fax
+86 351 7031519
Email
sales@RHFChem.com
Country
China
ProdList
2338
Advantage
56
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9413
Advantage
66
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42958
Advantage
64
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8843
Advantage
52
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View Lastest Price from 2-Bromopropionic acid manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
2-Bromopropionic acid 598-72-1
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-12
Hebei Yanxi Chemical Co., Ltd.
Product
2-Bromopropionic acid 598-72-1
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20tons
Release date
2023-10-12
Hebei Weibang Biotechnology Co., Ltd
Product
2-Bromopropionic acid 598-72-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-10-24

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