Mesterolone
- Product Name
- Mesterolone
- CAS No.
- 1424-00-6
- Chemical Name
- Mesterolone
- Synonyms
- proviron;mesterolon;MESTERELONE;testiwop;sh723;NSC-7504;NSC 75054;mesteranum;androviron;mestoranum
- CBNumber
- CB9691874
- Molecular Formula
- C20H32O2
- Formula Weight
- 304.47
- MOL File
- 1424-00-6.mol
Mesterolone Property
- Melting point:
- 208 °C
- alpha
- D20 +17.6° (c = 0.875 in CHCl3)
- Boiling point:
- 420.3±45.0 °C(Predicted)
- Density
- 1.156 g/cm3
- refractive index
- 17.6 ° (C=0.9, CHCl3)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, sparingly soluble in acetone, in ethyl acetate and in methanol
- pka
- 15.09±0.70(Predicted)
- Water Solubility
- 3mg/L at 20℃
- Merck
- 5916
- InChI
- InChI=1/C20H32O2/c1-12-10-14(21)11-13-4-5-15-16-6-7-18(22)19(16,2)9-8-17(15)20(12,13)3/h12-13,15-18,22H,4-11H2,1-3H3/t12-,13-,15-,16-,17-,18-,19-,20-/s3
- InChIKey
- UXYRZJKIQKRJCF-TZPFWLJSSA-N
- SMILES
- [C@@]12([H])CC[C@@]3([H])CC(=O)C[C@H](C)[C@]3(C)[C@@]1([H])CC[C@]1(C)[C@H](CC[C@@]21[H])O |&1:0,4,10,12,14,18,20,23,r|
- CAS DataBase Reference
- 1424-00-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xn,T,F
- Risk Statements
- 20/21/22-38-19-11-61-60
- Safety Statements
- 22-24/25-36/37/39-45-53
- WGK Germany
- 3
- RTECS
- BV8063400
- HS Code
- 29372900
- DEA Controlled Substances
- CSCN: 4000
CSA SCH: Schedule III
NARC: No
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H351Suspected of causing cancer
H362May cause harm to breast-fed children
H411Toxic to aquatic life with long lasting effects
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P263Avoid contact during pregnancy/while nursing.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P273Avoid release to the environment.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M7655
- Product name
- Mesterolone
- Purity
- analytical standard
- Packaging
- 100mg
- Price
- $95.1
- Updated
- 2024/03/01
- Product number
- 21171
- Product name
- Mesterolone
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 21171
- Product name
- Mesterolone
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $109
- Updated
- 2024/03/01
- Product number
- SHG0006368
- Product name
- MESTEROLONE
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $721.88
- Updated
- 2021/12/16
- Product number
- SHG0006368
- Product name
- MESTEROLONE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $1815
- Updated
- 2021/12/16
Mesterolone Chemical Properties,Usage,Production
Description
Mesterolone (Item No. 21171) is an analytical reference standard categorized as an anabolic androgenic steroid. Formulations containing mesterolone have been used in patients with low testosterone or symptoms of aging male syndrome. Mesterolone cannot be aromatized to estrogens, unlike other androgens. This compound is the active ingredient in different pharmaceutical preparations that have been used medically but have also been widely applied in sports in order to improve athlete performance. Mesterolone is regulated as a Schedule III drug in the United States. This product is intended for research and forensic applications.
Chemical Properties
White or yellowish crystalline powder.
Originator
Proviron,Schering,W. Germany,1967
Uses
Mesterolone is a synthetic androgen and a dihydrotestosterone derivative. Mesterolone is rarely used for replacement therapies due to its weak androgenic activity.
Definition
ChEBI: Mesterolone is a 3-oxo-5alpha-steroid. It is a structurally altered DHT hormone possessing the addition of a methyl group at the carbon one position. This allows the hormone to survive oral ingestion by protecting it from hepatic breakdown. This is one of the only oral anabolic steroids that is not C17-alpha alkylated (C17-aa) but instead carries the added methyl group.
Application
Mesterolone is a pharmacological agent that belongs to the group of androgens. It is an oral preparation and has been used in the treatment of infectious diseases, autoimmune diseases, and metabolic disorders. It has also been used as a matrix effect control in biological samples. The biological effects of it are mediated by its direct action on cells or through conversion to testosterone or dihydrotestosterone (DHT). These effects include increasing protein synthesis, promoting bone formation, lowering cholesterol levels, stimulating the production of red blood cells, and decreasing fat deposition.
Manufacturing Process
500 mg of 1α-methyl-androstan-17β-ol-3-one-17-acetate are heated under reflux for 90 minutes in a nitrogen atmosphere in 5 ml of 4% methanolic sodium hydroxide solution. The reaction mixture is then stirred into ice water,the precipitated product filtered with suction and recrystallized from isopropyl ether. 1α-Methyl-androstan-17β-ol-3-one melts at 203.5° to 205°C.
Therapeutic Function
Androgen
General Description
Mesterolone is a synthetic anabolic-androgenic steroid (AAS) and derivative of dihydrotestosterone (DHT). It is inactivated by 3α-hydroxysteroid dehydrogenase in skeleta muscules so it is considered a weak androgen. It is not a substrate for aromatase so it is not converted into estrogen. Mesterolone demonstrated to have minimal effect on sperm counts and levels of FSH or LH. Experiments of mesterolone serving as a potential treatment of depression are still undergoing.
Side effects
The main side effects are acne vulgaris, male pattern baldness, prostate enlargement, increased risk for prostate cancer, and increased risk for developing breast cancer.
Mesterolone Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Mesterolone manufacturers
- Product
- Mesterolone(Proviron) 1424-00-6
- Price
- US $12.00-8.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2024-05-11
- Product
- Mesterolone 1424-00-6
- Price
- US $1.00-68.00/g
- Min. Order
- 1g
- Purity
- 99.99%
- Supply Ability
- 1000kg
- Release date
- 2023-10-09
- Product
- Mesterolone (Proviron) 1424-00-6
- Price
- US $0.00/G
- Min. Order
- 1G
- Purity
- 20
- Supply Ability
- 20
- Release date
- 2024-04-11