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L-Arginine hydrochloride

Product Name
L-Arginine hydrochloride
CAS No.
1119-34-2
Chemical Name
L-Arginine hydrochloride
Synonyms
L-ARGININE HCL;Arginine HCL;ARGININE HYDROCHLORIDE;L-ARGININE MONOHYDROCHLORIDE;H-ARG-OH HCL;L-Arginine HCI;r-gene;argivene;levargin;ARG, HCL
CBNumber
CB9700536
Molecular Formula
C6H15ClN4O2
Formula Weight
210.66
MOL File
1119-34-2.mol
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L-Arginine hydrochloride Property

Melting point:
226-230 °C(lit.)
alpha 
22 º (c=8,6N HCl)
Boiling point:
235℃[at 101 325 Pa]
Density 
1.42
vapor pressure 
<1 Pa (20 °C)
FEMA 
3819 | L-ARGININE
storage temp. 
2-8°C
solubility 
H2O: 100 mg/mL
form 
powder
pka
1[at 20 ℃]
color 
white
PH
5.5-7.0 (25℃, 1M in H2O)
Odor
odorless
PH Range
5.5 - 7
optical activity
[α]20/D +22.0±0.5°, c = 5% in 5 M HCl
Water Solubility 
Soluble in water. Slightly soluble in hot alcohol.
Sensitive 
Hygroscopic
λmax
λ: 260 nm Amax: ≤0.2
λ: 280 nm Amax: ≤0.1
Merck 
14,780
BRN 
3631658
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
-8.5--3.24 at 25℃
CAS DataBase Reference
1119-34-2(CAS DataBase Reference)
EPA Substance Registry System
L-Arginine, monohydrochloride (1119-34-2)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
37-36/38-36/37/38-20/21/22
Safety Statements 
37/39-26-24/25-36
WGK Germany 
2
RTECS 
CF1995500
F 
3-10
TSCA 
Yes
HS Code 
29252000
Toxicity
LD50 orally in Rabbit: 12000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
181003
Product name
L-Arginine, Hydrochloride - CAS 1119-34-2 - Calbiochem
Packaging
50G
Price
$97.2
Updated
2024/03/01
Sigma-Aldrich
Product number
181003
Product name
L-Arginine, Hydrochloride - CAS 1119-34-2 - Calbiochem
Packaging
250G
Price
$147
Updated
2024/03/01
Sigma-Aldrich
Product number
8.16001
Product name
(S)-(+)-Arginine hydrochloride
Purity
for synthesis
Packaging
100G
Price
$47.9
Updated
2024/03/01
Sigma-Aldrich
Product number
181003
Product name
L-Arginine, Hydrochloride - CAS 1119-34-2 - Calbiochem
Packaging
1KG
Price
$546
Updated
2024/03/01
Sigma-Aldrich
Product number
11039
Product name
L-Arginine monohydrochloride
Purity
BioUltra, ≥99.5% (AT)
Packaging
100g
Price
$108
Updated
2024/03/01
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L-Arginine hydrochloride Chemical Properties,Usage,Production

Description

L-Arginine hydrochloride is a salt form of L-Arginine, where hydrochloric acid is added to enhance stability and solubility. Arginine hydrochloride is a L-alpha-amino acid. An essential amino acid that is physiologically active in the L-form. L-Arginine might be effective at lowering blood pressure, reducing the symptoms of angina and PAD , and treating erectile dysfunction due to a physical cause.

Chemical Properties

White crystalline powder

Uses

gastric acid depressant

Uses

L-Arginine monohydrochloride is used in the treatment of heart and circulatory diseases. It is a precursor of nitric oxide synthesis that induces vasodilation in vivo, there by relaxing blood vessels. It is also used in the treatment of angina and other cardiovascular problems. It is an important intermediate in the urea cycle and involved in the detoxification of nitrogenous wastes. It is commonly used in cell culture media and drug development.

Uses

An essential amino acid for human development. Precursor for nitric oxide. Ammonia detoxicant (hepatic failure); diagnostic aid (pituitary function).

Definition

ChEBI: Arginine hydrochloride is a L-alpha-amino acid.

brand name

R-Gene 10 (Pharmacia & Upjohn).

Biochem/physiol Actions

L-Arginine is considered as a semi essential amino acid. In most mammals including humans, L-Arginine synthesis occurs through intestinal-renal axis, from glutamine, glutamate and proline. Abnormal levels of L-Arginine is associated with the development of kidney and cardiovascular disease. L-arginine is found to decrease fat mass and visceral adiposity.

Side effects

L-arginine has some potential side effects to consider when taking it as a supplement. Some of the more common and benign side effects can include: nausea, diarrhea, bloating, and abdominal pain. However, L-arginine may result in some serious complications.

Safety Profile

Moderately toxic by intraperitoneal route. Mildly toxic by ingestion. An experimental teratogen. When heated to decomposition it emits very toxic fumes of NOx and HCl.

Purification Methods

A likely impurity is ornithine. Crystallise the salt from H2O at pH 5-7, by adding EtOH to 80% (v/v). [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 1841 1961, Beilstein 4 IV 2649.]

L-Arginine hydrochloride Preparation Products And Raw materials

Raw materials

Hydrochloric acid L(+)-Arginine Activated carbon Gelatin

Preparation Products

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L-Arginine hydrochloride Suppliers

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View Lastest Price from L-Arginine hydrochloride manufacturers

HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
Product
L-Arginine hydrochloride 1119-34-2
Price
US $999.00-666.00/g
Min. Order
1g
Purity
99%
Supply Ability
5000
Release date
2024-08-20
WUHAN FORTUNA CHEMICAL CO., LTD
Product
L-Arginine hydrochloride 1119-34-2
Price
US $0.00/KG
Min. Order
1KG
Purity
98.5～101.5%,USP38
Supply Ability
20tons/month
Release date
2021-06-23
Hebei Weibang Biotechnology Co., Ltd
Product
L-Arginine hydrochloride 1119-34-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-04

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