GYKI 52466 HYDROCHLORIDE

Product Name: GYKI 52466 HYDROCHLORIDE
CAS No.: 102771-26-6
Chemical Name: GYKI 52466 HYDROCHLORIDE
Synonyms: 466;2466;CS-813;GYKI-5;GYKI52;GYKI 52;Gyki Hcl;gyki52466;GYKI52466HCl;Gyki Hydrochloride
CBNumber: CB9701780
Molecular Formula: C17H16ClN3O2
Formula Weight: 329.78
MOL File: 102771-26-6.mol

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GYKI 52466 HYDROCHLORIDE Property

Boiling point:: 472.8±45.0 °C(Predicted)
Density: 1.39
storage temp.: Desiccate at RT
solubility: DMSO: 0.39 mg/mL
form: solid
pka: 8.14±0.20(Predicted)
color: yellow

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-26-36
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Tocris

Product number: 1454
Product name: GYKI52466dihydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $670
Updated: 2021/12/16

Tocris

Product number: 1454
Product name: GYKI52466dihydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $162
Updated: 2021/12/16

Usbiological

Product number: 255423
Product name: GYKI 52466 dihydrochloride
Packaging: 10mg
Price: $403
Updated: 2021/12/16

TRC

Product number: M303695
Product name: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
Packaging: 50mg
Price: $545
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 47448
Product name: 4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
Packaging: 10mg
Price: $620
Updated: 2021/12/16

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GYKI 52466 HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine is a non-competitive AMPA receptor antagonist and was found to have therapeutic potential for cocaine addiction treatment.

Definition

ChEBI: GYKI 52466 is a benzodiazepine.

Biological Activity

Selective non-competitive AMPA receptor antagonist (IC 50 values are 10-20, ~ 450 and >> 50 μ M for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. Has anti-proliferative effects in transformed cells. Also available as part of the AMPA Receptor Tocriset™ . Also available as part of the Kainate Receptor Tocriset™ .

storage

room temperature (desiccate)

GYKI 52466 HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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GYKI 52466 HYDROCHLORIDE Suppliers

Canada 1 China 54 Germany 2 India 1 Japan 1 Switzerland 2 United Kingdom 1 United States 13 Global 75

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2123
Advantage: 70

AdooQ BioScience, LLC

Tel: +1 (866) 930-6790
Fax: +1 (866) 333-9607
Email: info@adooq.com
Country: United States
ProdList: 2782
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32165
Advantage: 58

Cckinase, Inc.

Tel: +1 (732)236-3202
Email: sales@cckinase.com
Country: United States
ProdList: 2738
Advantage: 58

TargetMol Chemicals Inc.

Tel: +8613564774135
Email: zijue.cai@tsbiochem.com
Country: United States
ProdList: 19885
Advantage: 58

Aladdin Scientific

Tel: +1-+1(833)-552-7181
Email: sales@aladdinsci.com
Country: United States
ProdList: 52925
Advantage: 58

United States Biological

Tel: --
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Email: sales@advtechind.com
Country: United States
ProdList: 6075
Advantage: 58

ApexBio Technology

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Fax: --
Email: sales@apexbt.com
Country: United States
ProdList: 6251
Advantage: 58

Alfa Chemistry

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Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

BOC Sciences

Tel: 16314854226
Email: info@bocsci.com
Country: United States
ProdList: 9923
Advantage: 65

United States Biological

Tel: --
Fax: --
Email: chemicals@usbio.net
Country: United States
ProdList: 6214
Advantage: 80

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

Riedel-de Haen AG

Tel: --
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Country: United States
ProdList: 6773
Advantage: 87

102771-26-6, GYKI 52466 HYDROCHLORIDERelated Search:

Benzophenone hydrazone GYKI 52466 HYDROCHLORIDE ACETONE AZINE

gyki52466

4-(8-METHYL-9H-1,3-DIOXOLO[4,5-H][2,3]BENZODIAZEPIN-5-YL)-BENZENAMINE HYDROCHLORIDE

GYKI 52466 HYDROCHLORIDE

4-(8-Methyl-(9H)-1,3-dioxolo[4.5-h][2.3]benzodiazepine-5-yl)benzenaminehydrochloride

GYKI52466HCl

1-(4-Aminophenyl)-4-methyl-7,8-(methylenedioxy)-5H-2,3-benzodiazepine

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepine-5-yl)aniline

1-(p-Aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine hydrochloride

4-(8-Methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)benzenamine

Benzenamine, 4-(8-methyl-9H-1,3-dioxolo(4,5-H)(2,3)benzodiazepin-5-yl)-

Gyki Hcl

4-(8-Methyl-9H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)-benzenaminedihydrochloride

GYKI 52466 dihydrochloride

Gyki Hydrochloride

4-(8-methyl-8,9-dihydro-7H-[1,3]dioxolo[4,,5,:4,5]benzo[1,2-d][1,2]diazepin-5-yl)aniline

GYKI52466;GYKI-52466

CS-813

2466

466

GYKI 52

GYKI-5

GYKI52

102771-26-6

C17H15N3O22HCl

C17H15N3O2HCl

Cell Signaling and Neuroscience

Cell Biology

BioChemical

Ionotropic Glutamate Receptor Modulators

Ion Channels

Ligand-Gated Ion Channels

Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals