ChemicalBook > CAS DataBase List > HARMALINE

HARMALINE

Product Name
HARMALINE
CAS No.
304-21-2
Chemical Name
HARMALINE
Synonyms
Armalin;Hartline;HARMALINE;Harmidine;NSC 407285;Harmaline>Harmaline-RM;HARMALINE,99%;DIHYDROHARMINE;dihydro-harmin
CBNumber
CB9711132
Molecular Formula
C13H14N2O
Formula Weight
214.26
MOL File
304-21-2.mol
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HARMALINE Property

Melting point:
232-234 °C(lit.)
Boiling point:
354.4°C (rough estimate)
alpha 
±0°
Density 
1.0850 (rough estimate)
refractive index 
1.6450 (estimate)
storage temp. 
-10 to -25°C
Water Solubility 
Slightly soluble in water
solubility 
DMF: 1.4 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 0.25 mg/ml; Ethanol: 0.5 mg/ml
form 
powder
pka
4.2(at 25℃)
color 
Light orange to Yellow to Green
Merck 
14,4613
BRN 
207310
LogP
2.251 (est)
CAS DataBase Reference
304-21-2(CAS DataBase Reference)
NIST Chemistry Reference
Harmaline(304-21-2)
EPA Substance Registry System
3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl- (304-21-2)
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Safety

Hazard Codes 
Xn
Risk Statements 
25-20/21/22
Safety Statements 
22-24/25-36
RIDADR 
1544
WGK Germany 
3
RTECS 
UU9800000
HS Code 
2939.80.0000
HazardClass 
6.1(b)
PackingGroup 
III
Hazardous Substances Data
304-21-2(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H371May cause damage to organs

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89700
Product name
Harmaline
Purity
phyproof? Reference Substance
Packaging
50MG
Price
$231
Updated
2025/07/31
Sigma-Aldrich
Product number
H-169
Product name
Harmaline solution
Purity
1?mg/mL in methanol, certified reference material, ampule of 1?mL, Cerilliant?
Packaging
1ML
Price
$172
Updated
2025/07/31
Sigma-Aldrich
Product number
51330
Product name
Harmaline
Packaging
1g
Price
$81.5
Updated
2025/07/31
TCI Chemical
Product number
H1237
Product name
Harmaline
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$82
Updated
2025/07/31
TCI Chemical
Product number
H1237
Product name
Harmaline
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$248
Updated
2025/07/31
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HARMALINE Chemical Properties,Usage,Production

Uses

CNS stimulant, antiparkinsonian agent

Uses

CNS stimulant; may act through NMDA receptors. Reversible inhibitor of MAO-A

Definition

ChEBI: A harmala alkaloid in which the harman skeleton is methoxy-substituted at C-7 and has been reduced across the 3,4 bond.

Synthesis Reference(s)

Canadian Journal of Chemistry, 37, p. 1851, 1959 DOI: 10.1139/v59-272

Biological Activity

CNS stimulant; may act through NMDA receptors

Purification Methods

Recrystallise harmaline from MeOH and sublime it at high vacuum. It has UV in MeOH a

HARMALINE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from HARMALINE manufacturers

RongNa Biotechnology Co.,Ltd
Product
HARMALINE 304-21-2
Price
US $10.00/ASSAYS
Min. Order
1ASSAYS
Purity
99%
Supply Ability
1 ton
Release date
2025-08-21
Shaanxi Xianhe Biotech Co., Ltd
Product
harmaline 304-21-2
Price
US $0.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
1000kg
Release date
2025-04-25
Changsha Staherb Natural Ingredients Co., Ltd.
Product
HARMALINE; HARMINE HYDROCHLORIDE 304-21-2
Price
US $0.00/KG
Min. Order
1KG
Purity
≥98% HPLC
Supply Ability
1000KG
Release date
2022-09-20

304-21-2, HARMALINERelated Search:


  • 1-METHYL-7-METHOXY-3,4-DIHYDRO-BETA-CARBOLINE
  • TIMTEC-BB SBB003407
  • 1-Methyl-7-methoxy-3,4-dihydroxy-beta-carboline
  • 1-methyl-7-methoxy-3,4-dihydro-β-carboline
  • HARMALINE(EXTRACTFORMPEGANUMHARMALAROOTS)
  • 3,4-Dihydro-7-methoxy-1-methyl-beta-carboline 3,4-Dihydro-7-methoxy-1-methyl-9H-pyrido[3,4-b]indole Dihydroharmine
  • NSC 407285
  • PYRIDE(3,4-B)INDOLE,4,9-DIHYDRO-7-METHOXY-1-METHYL-
  • 1-Methyl-7-methoxy-3,4-dihydro-β-carboline, Dihydroharmine, Harmalol methyl ether, 4,9-Dihydro-7-methoxy-1-methyl-3H-pyrido[3,4-b]indole
  • 7-Methoxy-1-methyl-4,9-dihydro-3H-pyrido[3,4-b]indole
  • 3,4-Dihydro-7-methoxy-1-methyl-9-pyrid(3,4-b)indole
  • 7-methoxy-1-methyl-3,4-dihydro-2H-pyrido[3,4-b]indole
  • DIHYDROHARMINE
  • HARMALINE
  • HARMALOL METHYL ETHER
  • 4,9-DIHYDRO-7-METHOXY-1-METHYL-3H-PYRIDO[3,4-B]INDOLE
  • 3,4-DIHYDROHARMIN
  • 3,4-DIHYDROHARMINE
  • 3,4-DIHYDRO-7-METHOXY-1-METHYL-9H-PYRIDO[3,4-B]-INDOLE
  • 3,4-DIHYDRO-7-METHOXY-1-METHYL-BETA-CARBOLINE
  • 3,4-dihydro-7-methoxy-1-methyl-9-pyrido(3,4-b)indole
  • 3H-Pyrido[3,4-b]indole, 4,9-dihydro-7-methoxy-1-methyl-
  • 4-b)indole,4,9-dihydro-7-methoxy-1-methyl-3h-pyrido(
  • 7-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline
  • Armalin
  • dihydro-harmin
  • Harmidine
  • Harmine, dihydro-
  • O-Methylharmalol
  • Harmaline, mixture of Harmine
  • Harmaline&gt
  • HARMALINE,99%
  • Hartline
  • Harmaline pure, 98%
  • Harmaline, ≥ 98.0%
  • Harmaline-RM
  • Harmaline solution
  • 304-21-2
  • 304-21-1
  • Heterocyclic Building Blocks
  • Indoles
  • Building Blocks
  • Inhibitors
  • Indoles and derivatives
  • Heterocyclic Compounds