Thiamine disulfide
- Product Name
- Thiamine disulfide
- CAS No.
- 67-16-3
- Chemical Name
- Thiamine disulfide
- Synonyms
- TDS;SSB1;Daiomin;Apren S;Daisazin;Neolamin;Alitia S;FeidMin 5;BISTHIAMINE;Algoneurina
- CBNumber
- CB9722783
- Molecular Formula
- C24H34N8O4S2
- Formula Weight
- 562.71
- MOL File
- 67-16-3.mol
Thiamine disulfide Property
- Melting point:
- 177° with intense yellow coloration
- Boiling point:
- 886.1±65.0 °C(Predicted)
- Density
- 1.1966 (rough estimate)
- refractive index
- 1.7400 (estimate)
- storage temp.
- Refrigerator
- solubility
- DMSO (Slightly), Methanol (Slightly)
- form
- Solid
- pka
- 14.10±0.10(Predicted)
- color
- White
- Merck
- 14,9297
- CAS DataBase Reference
- 67-16-3(CAS DataBase Reference)
- EPA Substance Registry System
- Formamide, N,N'-[dithiobis[2-(2-hydroxyethyl)-1-methyl-2,1-ethenediyl]]bis[N-[(4-amino-2-methyl-5-pyrimidinyl)methyl]- (67-16-3)
Safety
- RTECS
- LQ2715000
- HS Code
- 2936.22.0000
- Toxicity
- LD50 intravenous in mouse: 500mg/kg
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- T0176
- Product name
- Thiamine Disulfide Hydrate
- Purity
- >98.0%(T)
- Packaging
- 25g
- Price
- $146
- Updated
- 2024/03/01
- Product number
- T344278
- Product name
- ThiamineDisulfide
- Packaging
- 2.5g
- Price
- $75
- Updated
- 2021/12/16
- Product number
- J50009
- Product name
- Thiaminedisulfide
- Packaging
- 25g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- API0004386
- Product name
- THIAMINE DISULFIDE
- Purity
- 95.00%
- Packaging
- 25G
- Price
- $210.11
- Updated
- 2021/12/16
- Product number
- P052
- Product name
- Thiaminedisulfide
- Packaging
- 100g
- Price
- $481
- Updated
- 2021/12/16
Thiamine disulfide Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Arcalion,Servier,France,1974
Uses
Thiamine is a essential nutrient required for carbohydrate metabolism; also involved in nerve function. Biosynthesized by microorganisms and plants. Dietary sources include whole grains, meat products , vegetables, milk, legumes and fruit. Also present in rice husks and yeast. Converted in vivo to Thiamine diphosphate, a coenzyme in the decarboxylation of α-keto acids. Chronic deficiency may lead t o neurological impairment, bariberi, Wernicke-Korsakoff syndrome.
Uses
Thiamine disulfide is an antioxidant, inhibiting lipid peroxidation in rat liver microsomes and free radical oxidation of oleic acid in vitro. Thiamine disulfide has been explored as a potent inhibitor of HIV-1.
Definition
ChEBI: Thiamine disulfide is an aminopyrimidine, a homoallylic alcohol, a member of formamides and an organic disulfide.
Manufacturing Process
20 parts by weight of thiamin are dissolved in 25 parts of water, a cold
solution of 5 parts by weight of caustic soda in 25 parts of water added and
the mixture oxidized with a solution of 2.4 parts by weight of caustic soda and
20 parts by weight of potassium ferric cyanide in 80 parts of water while
stirring in the cold. The liquid is then evaporated to dryness and the resulting
oxidation product extracted with warm butyl alcohol.
The butyl-alcoholic solution is evaporated in vacuo and the residue dissolved
with gentle heating in 25 parts by volume of methyl alcohol. 100 parts by
volume of acetone are added, the solution filtered and further quantities of
acetone added, whereupon crystallization sets in. Yield: 12.2 parts by weight
of the pure product, having the melting point 177° to 179°C.
Therapeutic Function
Enzyme cofactor vitamin
Thiamine disulfide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Thiamine disulfide manufacturers
- Product
- Thiamine disulfide 67-16-3
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 100kg
- Release date
- 2019-05-23