AROTINOLOL HCL
- Product Name
- AROTINOLOL HCL
- CAS No.
- 68377-91-3
- Chemical Name
- AROTINOLOL HCL
- Synonyms
- ARL;s596;Almarl;Acemail;Astonil;Anasirol;thiazolehcl;AROTINOLOL HCL;AROTINOLOL HYDROCHLORIDE;AROTINOLOL HCL USP/EP/BP
- CBNumber
- CB9723043
- Molecular Formula
- C15H22ClN3O2S3
- Formula Weight
- 408
- MOL File
- 68377-91-3.mol
AROTINOLOL HCL Property
- Melting point:
- 234-235.5° (dec)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- Water Solubility
- Practically insoluble in water
- form
- powder to crystal
- color
- White to Orange to Green
- Merck
- 14,791
Safety
- RIDADR
- UN 2811 6.1/PG III
- RTECS
- XM8301000
- HS Code
- 2934.99.3000
- HazardClass
- 6.1
- PackingGroup
- III
- Toxicity
- LD50 in mice (mg/kg): 86 i.v., >360 i.p., >5000 orally (Hara)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A3145
- Product name
- Arotinolol Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 50mg
- Price
- $126
- Updated
- 2024/03/01
- Product number
- A3145
- Product name
- Arotinolol Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 250mg
- Price
- $402
- Updated
- 2021/12/16
- Product number
- A771503
- Product name
- Arotinolol Hydrochloride
- Packaging
- 10mg
- Price
- $1135
- Updated
- 2021/12/16
- Product number
- 37622
- Product name
- Arotinololhydrochloride,98%(HPLC)
- Purity
- 98%(HPLC)
- Packaging
- 250MG
- Price
- $445.76
- Updated
- 2021/12/16
- Product number
- API0016528
- Product name
- AROTINOLOL HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $496.2
- Updated
- 2021/12/16
AROTINOLOL HCL Chemical Properties,Usage,Production
Description
Arotinolol hydrochloride i s a β-adrenergic blocker with weak α-antagonistic properties, useful in the treatment of hypertension.
Originator
Sumitomo (Japan)
Uses
Arotinolol is both and alpha- and beta-adrenoceptor antagonist and is used to treat essential tremors and hypertension.
Definition
ChEBI: Arotinolol hydrochloride is an aromatic amide and a member of thiophenes.
Manufacturing Process
To a solution of 2-mercapto-4-(5'-carbamoyl-2'-thiophenyl)thiazole, 3.2 g in
20 ml of 0.3 % aqueous sodium hydroxide solution, 1-chloro-3-tbutylaminopropanol,
12.64 g in 20 ml of methanol was added, while the
temperature was maintained at 20°C.
The reaction solution was stirred at room temperature for 4 h, and then
condensed to a half volume in vacuo. The residual solution, added with 100 ml
of water, was extracted with chloroform. The chloroform extract was washed
with water, dried over anhydrous magnesium sulfate and evaporated in vacuo
to give 4.8 g of 2-(3'-t-butylamino-2'-hydroxypropylthio)-4-(5'-carbamoyl-2'-
thiophenyl)thiazole, as crystals, melting point 234°-235.5°C (dec.,
recrystallized from methanol/water).
In practice it is usually used as hydrochloride.
brand name
ALMARL
Therapeutic Function
Beta-adrenergic blocker
AROTINOLOL HCL Preparation Products And Raw materials
Raw materials
Preparation Products
AROTINOLOL HCL Suppliers
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- --
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- Country
- China
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- China
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- China
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- China
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- 0731-85526065 13308475853
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- China
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- Fax
- +1-888-520-1075 / +1-503-283-1987
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- Americas
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View Lastest Price from AROTINOLOL HCL manufacturers
- Product
- Arotinolol Hydrochloride 68377-91-3
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2024-04-24
- Product
- AROTINOLOL HCL 68377-91-3
- Price
- US $1.00-1.00/KG
- Min. Order
- 1g
- Purity
- 99%
- Supply Ability
- 50tons
- Release date
- 2020-05-11
- Product
- AROTINOLOL HCL 68377-91-3
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons min
- Release date
- 2021-08-11