ChemicalBook > CAS DataBase List > 3-Cyclohexylaminopropanesulfonic Acid

3-Cyclohexylaminopropanesulfonic Acid

Product Name
3-Cyclohexylaminopropanesulfonic Acid
CAS No.
1135-40-6
Chemical Name
3-Cyclohexylaminopropanesulfonic Acid
Synonyms
CAPS;3-(CYCLOHEXYLAMINO)-1-PROPANESULFONIC ACID;Seals;CAPS3;Push-on caps;CAPS, ULTROL;CAPS ULTRAPURE;CAPS, free acid;CAPS Buffer salt;CAPS, ULTROL Grade
CBNumber
CB9732670
Molecular Formula
C9H19NO3S
Formula Weight
221.32
MOL File
1135-40-6.mol
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3-Cyclohexylaminopropanesulfonic Acid Property

Melting point:
>300 °C(lit.)
Density 
1.1809 (rough estimate)
bulk density
400kg/m3
vapor pressure 
0Pa at 25℃
refractive index 
1.5250 (estimate)
Flash point:
>110℃
storage temp. 
room temp
solubility 
H2O: 0.5 M at 20 °C, clear
form 
Powder/Solid
color 
White
Odor
Odorless
PH Range
3 - 7
PH
3.0-7.0 (20℃, 0.5M in H2O)
pka
10.4(at 25℃)
Water Solubility 
9 g/100 mL (20 ºC)
λmax
λ: 260 nm Amax: ≤0.04
λ: 280 nm Amax: ≤0.04
Merck 
14,1767
BRN 
2835588
Stability:
Stable. Incompatible with strong oxidizing agents.
LogP
0.3 at 25℃
CAS DataBase Reference
1135-40-6(CAS DataBase Reference)
EPA Substance Registry System
1-Propanesulfonic acid, 3-(cyclohexylamino)- (1135-40-6)
Absorption
≤0.2 at 260 in H2O at 0.5M
≤0.2 at 280 in H2O at 0.5M
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/38-36/37/38-22-20/21/22-40/22
Safety Statements 
26-36/37/39-37/39-24/25-22-23-36
WGK Germany 
3
RTECS 
TZ6395000
F 
34
TSCA 
Yes
HS Code 
29213099
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
BR702885
Product name
BRAND<SUP>®</SUP> combi-pack caps and seal for Transferpettor
Purity
1000-5000 &#956;L, 2 PP caps, 1 PE seal
Packaging
1 set
Price
$12.5
Updated
2025/07/31
Sigma-Aldrich
Product number
BR702885
Product name
BRAND® combi-pack caps and seal for Transferpette®
Purity
for Transferpettor 1000-5000 μL
Packaging
1SET
Price
$12.5
Updated
2023/01/07
Sigma-Aldrich
Product number
29337
Product name
CAPS
Purity
BioUltra, ≥99.0% (TLC)
Packaging
25g
Price
$70.6
Updated
2023/01/07
Sigma-Aldrich
Product number
29337
Product name
CAPS
Purity
BioUltra, ≥99.0% (TLC)
Packaging
100g
Price
$214
Updated
2023/01/07
TCI Chemical
Product number
C0921
Product name
3-Cyclohexylaminopropanesulfonic Acid [Good's buffer component for biological research]
Purity
>98.0%(T)
Packaging
25g
Price
$32
Updated
2025/07/31
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3-Cyclohexylaminopropanesulfonic Acid Chemical Properties,Usage,Production

Chemical Properties

White/clear crystalline powder

Description

3-Cyclohexylaminopropanesulfonic Acid, also known as 3-(Cyclohexylamino)-1-propanesulfonic acid (CHAPS) or N-Cyclohexyl-3-aminopropanesulfonic acid, is a detergent with a high affinity for basic proteins that can be used to extract these proteins from biological samples and solubilize them. CHAPS is a type of ampholyte, which means it has both anionic and cationic groups.

Uses

3-Cyclohexylaminopropanesulfonic Acid buffer salt is used to formulate CAPS buffer, a zwitterionic buffer that is useful in the range of pH 7.9-11.1. CAPS buffer is widely used in Western and immunoblotting experiments as well as protein sequencing and identification. Used in the electrotransfer of proteins to PVDF (sc-3723) or nitrocellulose membranes (sc-3718, sc-3724). The high pH of this buffer makes it useful for the transfer of proteins with a pI > 8.5. CAPS is not one of the original Good's buffers, although it has a similar structure to the other propanesulfonic acids and was selected as a highly water soluble buffering reagent with an optimum buffering pH of 10.4 and minimal reactivity with enzymes or proteins, minimal salt effects. It is a biological buffer.

Definition

ChEBI: Cyclohexylaminopropanesulfonic acid is an amine.

Flammability and Explosibility

Not classified

References

[1] David A. Paulls, A. Townshend. “Sensitized determination of sulfite using flow injection with chemiluminescent detection.” Analyst 6 1 (1995): 467–469.
[2] Takashi Yoshitake. “Simultaneous determination of norepinephrine, serotonin, and 5-hydroxyindole-3-acetic acid in microdialysis samples from rat brain by microbore column liquid chromatography with fluorescence detection following derivatization with benzylamine.” Analytical biochemistry 312 2 (2003): 125–33.
[3] Keiichi Fujimori. “Determination of Sulfide with Acidic Permanganate Chemiluminescence for Development of Deep-sea in-situ Analyzers.” Analytical Sciences 27 2 (2011): 183–186.

3-Cyclohexylaminopropanesulfonic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-Cyclohexylaminopropanesulfonic Acid Suppliers

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View Lastest Price from 3-Cyclohexylaminopropanesulfonic Acid manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
CAPS 1135-40-6
Price
US $0.00/Kg/Drum
Min. Order
1KG
Purity
99%min
Supply Ability
500kgs
Release date
2021-08-27
Hebei Zhuanglai Chemical Trading Co Ltd
Product
3-Cyclohexylaminopropanesulfonic Acid 1135-40-6
Price
US $79.00-38.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-11-22
Hebei Chuanghai Biotechnology Co., Ltd
Product
N-Cyclohexyl-3-aminopropanesulfonic acid 1135-40-6
Price
US $30.00-10.00/KG
Min. Order
50KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-25

1135-40-6, 3-Cyclohexylaminopropanesulfonic AcidRelated Search:

Dicyclohexylamine Cyclohexylamine Cyclohexylamine hydrochloride Hyaluronic acid Folic acid 1,3-Propane sultone Isocyanatocyclohexane Ethyl 2-(Chlorosulfonyl)acetate Sodium p-styrenesulfonate Citric acid Ascoric Acid N-CYCLOHEXYLFORMAMIDE N-Cyanoimido-S,S-dimethyl-dithiocarbonate N-Cyanoethyl-N-methylaniline N-Cyanoethyl-hydroxyethyl aniline CHES N-Cyclohexyl-4-methylbenzenesulfonamide N-Cyclohexylmaleimide

  • N-Cyclohexyl-3-aMinopropanesulfonic acid (CAPS)
  • CAPS, free acid
  • BRAND? push-on cap for Technicon Analyzer
  • Push-on caps
  • BRAND? combi-pack caps and seal for Transferpette
  • Seals
  • BRAND? strip of 8 lids, for 96 tube rack
  • BRAND? cap for UV-cuvette micro
  • CAPS Vetec(TM) reagent grade, >=98%
  • TUNGSTIC ACID SODIUM SALT ACS GRADE
  • CAPS 〔Cyclohexylaminopropanesulfonic Acid〕
  • 3-(Cyclohexylamino)-1-propanesulphonic acid for synthesis
  • CAPS, ULTROL
  • 3-(cyclohexylamino)-1-propanesulfonic
  • 3-(cyclohexylamino)-1-propanesulfonicaci
  • CAPS(-(Cyclohexylamino)-1-propanesulfonic acid)
  • 3-(Cclohexylamino)-1-propanesulfonic acid
  • 1-Propanesulfonic acid, 3-(cyclohexylamino)-
  • 3-(Cyclohexylamino)-1-propanesuhinic acid (CAPS)
  • CAPS 3-(Cyclohexylamino)-1-propanesulfonic acid
  • CAPS, Molecular Biology Grade 3-(Cyclohexylamino)-1-propanesulfonic acid, Molecular Biology Grade
  • CAPS, ULTROL Grade
  • 3-cyclohexylaminopropane-1-sulphonic acid
  • CAPS, 99% (3-CYCLOHEXYLAMINO-1-PROPANE-S ULFONIC ACID)
  • CHOLESTERYL PALMITATE 98+%
  • 3-(CYCLOHEXYLAMINO)-PROPANE SULFONIC ACID (CAPS)
  • CAPS, MOLECULAR BIOLOGY GRADE
  • 3-(CYCLOHEXYLAMINO)-1-PROPANESULFONIC ACID (CAPS)
  • CAPS, for biochemistry
  • N-Cyclohexyl-3-aminopropanesulfonic acid
  • CAPS ULTRAPURE
  • 3-(Cyclohexylamino)-1-propanesulphonic acid >98%
  • Swagelok(R) 400C,BRASS CAPS 1/4" PK6
  • Swagelok(R) 200C,BRASS CAPS 1/8" PK6
  • Swagelok(R) 400C,SS CAPS 1/4" PK2
  • CAPS,99%,for biochemistry
  • 3-(Cyclohexylamino)-1-propanesuhinic acid
  • N-Cyclohexyl-3-aminopropanesulfonic acid ,99%
  • CAPS
  • CYCLOHEXYLAMINOPROPANESULFONIC ACID
  • LABOTEST-BB LT00159602
  • 3-CYCLOHEXYLAMINO-PROPANE-1-SULFONIC ACID
  • 3-(CYCLOHEXYLAMINO)-1-PROPANESULFONIC ACID
  • 3-(CYCLOHEXYLAMINO)-1-PROPANESULPHONIC ACID
  • CAPS3
  • 3-cyclohexylaminopropane-1-sulphoni
  • N-Cyclohexyl-3-aminopropanesulfonic acid, 98%, for bio
  • CYCLOHEXYLAMINPROPANSAEURE 100 G
  • N-Cyclohexyl-3-aminopropanesulfonic acid CAS 1135-40-6
  • 3-(cyclohexamino) -1-propanesulfonic acid
  • BORAGE OIL 84012-16-8
  • CAPS, 3-(N- Cyclohexylamino)-1- propanesulfonic acid
  • 3-CYCLOHEXYLAMINOPROPANESULFONIC ACID
  • CAPS-3-Cyclohexylaminopropanesulfonic Acid
  • 3-(Cyclohexane)-1-propanic acid
  • N-Cyclohexyl-3-aminopropanesulfonic acidz
  • CAPS, 10 mM in DMSO
  • BUFFER SOLUTION, PH 10.0