ChemicalBook > CAS DataBase List > D(-)-AMETHOPTERIN

D(-)-AMETHOPTERIN

Product Name
D(-)-AMETHOPTERIN
CAS No.
51865-79-3
Chemical Name
D(-)-AMETHOPTERIN
Synonyms
6-MTX(D);R-Methotrexate;d-methotrexate;Einecs 257-482-2;D(-)-AMETHOPTERIN;D-(-)-AMETHOPTERIN HYDRATE;Methotrexate Impurity 6(EP-F);(-) - AMETHOPTERIN - D - METHOTREXATE;D(-)-4-AMINO-N10-METHYLPTEROYLGLUTAMIC ACID;Methotrexate Impurity 6（Methotrexate EP Impurity F）
CBNumber
CB9739301
Molecular Formula
C20H22N8O5
Formula Weight
454.44
MOL File
51865-79-3.mol
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D(-)-AMETHOPTERIN Property

Melting point:
195 °C
Boiling point:
561.26°C (rough estimate)
Density 
1.4080 (rough estimate)
refractive index 
1.6910 (estimate)
storage temp. 
-20°C
solubility 
Aqueous Base (Slightly, Heated, Sonicated), DMSO (Slightly), Methanol (Slightly）
form 
Solid
pka
3.47±0.10(Predicted)
color 
Dark Yellow to Very Dark Yellow
Stability:
Hygroscopic
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Safety

Hazard Codes 
T
Risk Statements 
61-46-25-36/37/38-60-23/24/25
Safety Statements 
53-45-28A-36/37/39-26-22
RIDADR 
UN 1544 6.1/PG 3
RTECS 
MA1224000
HS Code 
29335995
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H341Suspected of causing genetic defects

Precautionary statements

P202Do not handle until all safety precautions have been read and understood.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
1413988
Product name
(?)-Amethopterin
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
5mg
Price
$1430
Updated
2024/03/01
TRC
Product number
M260665
Product name
(R)-Methotrexate
Packaging
25mg
Price
$2775
Updated
2021/12/16
TRC
Product number
M260665
Product name
(R)-Methotrexate
Packaging
1mg
Price
$180
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
52122
Product name
(R)-Methotrexate
Packaging
1mg
Price
$650
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0002180
Product name
D-(-)-AMETHOPTERIN
Purity
95.00%
Packaging
25MG
Price
$650.33
Updated
2021/12/16
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D(-)-AMETHOPTERIN Chemical Properties,Usage,Production

Chemical Properties

Solid

Uses

R-Methotrexate is an enantiomer of Methotrexate (M260675), a folic acid antagonist. Used as a antineoplastic and antirheumatic.

D(-)-AMETHOPTERIN Preparation Products And Raw materials

Raw materials

Preparation Products

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51865-79-3, D(-)-AMETHOPTERINRelated Search:

Methotrexate Related Compound E (50 mg) (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, hemihydrochloride) Aminopterin N-(4-(METHYLAMINO)BENZOYL)-L-GLUTAMIC ACID Methotrexate EP Impurity G 2,4-DIAMINO-6-(HYDROXYMETHYL)PTERIDINE L-Glutamic acid, N-[4-[[ (2-amino-1, 4-dihydro-4-oxo-6-pteridinyl)meth yl]methylamino]benzoyl]- 4-[Methyl[(2-amino-4-hydroxypteridine)-6-ylmethyl]amino]benzoic acid L-AMETHOPTERIN HYDRATE,L-(+)-AMETHOPTERIN HYDRATE,(+)-AMETHOPTERIN HYDRATE Methotrexate (plus-minus)-amethopterin,dl-amethopteri 7-Hydroxy Amethopterin-d3 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid-d3 D-AMETHOPTERIN HYDRATE, 95 7-Hydroxy Amethopterin, 4-Amino-7-hydroxy-10-methylpteroylglutamic Acid D(-)-AMETHOPTERIN HYDRATE, 98 L(+)-AMETHOPTERIN DIHYDRATE (+)-Amethopterin-methyl-d3, 4-Amino-10-methylpteroylglutamic-methyl-d3 Acid DL-AMETHOPTERIN HYDRATE

  • d-methotrexate
  • n-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-d-glutamicacid
  • D(-)-AMETHOPTERIN
  • D-(-)-AMETHOPTERIN HYDRATE
  • D(-)-4-AMINO-N10-METHYLPTEROYLGLUTAMIC ACID
  • D-(-)-N-(2,4-diamino-6-pteridinyl(dimethylamino)benzoyl)glutamic acid
  • R-Methotrexate (5 mg) ((R)-2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic acid)
  • R-Methotrexate
  • Methotrexate Impurity 6(EP-F)
  • D-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]- (9CI)
  • (-) - AMETHOPTERIN - D - METHOTREXATE
  • 6-MTX(D)
  • N-[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]-D-glutamic acid
  • D-Glutamic acid, N-(4-(((2,4-diamino-6-pteridyl)methyl)methylamino)benzoyl)-
  • Einecs 257-482-2
  • Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-, D-
  • D-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-
  • Methotrexate Impurity 6（Methotrexate EP Impurity F）
  • (4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-D-glutamic acid
  • Methotrexate EP Impurity F Disodium Salt ((R)-Methotrexate Disodium Salt)
  • MethotrexateEPImpurityFDisodiumSalt-MethotrexateDisodiumSalt)
  • (R)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino) benzamido)pentanedioic acid
  • 51865-79-3
  • 331717-13-2
  • C20H22N8O5