ChemicalBook > CAS DataBase List > Genipin

Genipin

Product Name
Genipin
CAS No.
6902-77-8
Chemical Name
Genipin
Synonyms
enipin;GENIPIN;Jingping;Genipin>GENIPIN(SH);GENIPIN(RG);(+)-Genipin;Genipin(AS);Genipin, >=98%;Gardenia Fruit P.E
CBNumber
CB9767199
Molecular Formula
C11H14O5
Formula Weight
226.23
MOL File
6902-77-8.mol
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Genipin Property

Melting point:
118.0 to 123.0 °C
Boiling point:
287.83°C (rough estimate)
Density 
1.1230 (rough estimate)
refractive index 
1.4720 (estimate)
storage temp. 
Inert atmosphere,Room Temperature
solubility 
DMSO: ≥25mg/mL
form 
powder
pka
12.06±0.60(Predicted)
color 
White to Almost white
λmax
240nm(MeOH)(lit.)
InChI
InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
InChIKey
AZKVWQKMDGGDSV-BCMRRPTOSA-N
SMILES
[C@@H]1(O)OC=C(C(OC)=O)[C@@]2([H])CC=C(CO)[C@@]12[H]
CAS DataBase Reference
6902-77-8(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
22
Safety Statements 
3/14-36/37/39
RIDADR 
UN 2811 6.1/PG 3
WGK Germany 
3
RTECS 
GY5828000
HazardClass 
6.1
PackingGroup 
III
HS Code 
29329990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G4796
Product name
Genipin
Purity
≥98% (HPLC), powder
Packaging
25mg
Price
$134
Updated
2024/03/01
Sigma-Aldrich
Product number
PHL80458
Product name
Genipin
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$465
Updated
2024/03/01
Sigma-Aldrich
Product number
G4796
Product name
Genipin
Purity
≥98% (HPLC), powder
Packaging
125mg
Price
$532
Updated
2024/03/01
TCI Chemical
Product number
G0458
Product name
Genipin
Purity
>97.0%(GC)
Packaging
25mg
Price
$57
Updated
2024/03/01
TCI Chemical
Product number
G0458
Product name
Genipin
Purity
>97.0%(GC)
Packaging
100mg
Price
$174
Updated
2024/03/01
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Genipin Chemical Properties,Usage,Production

Chemical Properties

It is a white crystalline powder that is soluble in organic solvents such as methanol, ethanol, and DMSO. It is derived from the fruit of Gardenia jasminoides Ellis.

Uses

Genipin is an active aglycone derived from geniposide, an iridoid glycoside found in the fruit of Gardenia jasminoides Ellis. It has been used in traditional Chinese medicine and is a hydrolytic product of geniposide. Genipin is also known for its inhibitory effect on uncoupling protein 2 (UCP2).

Uses

Genipin has been used:

  • in chemosensitivity assay
  • in the preparation of recombinant human (rh)-odontogenic ameloblast-associated protein (ODAM) -impregnated collagen gel and in vitro mineralization assay
  • in genipin gel preparation

Definition

ChEBI: Genipin is an iridoid monoterpenoid. It has a role as an uncoupling protein inhibitor, a hepatotoxic agent, an apoptosis inhibitor, an antioxidant, an anti-inflammatory agent and a cross-linking reagent.

General Description

Genipin is a natural cross linking agent, which is extracted from gardenia fruit. It prevents lipid peroxidation and production of nitric oxide. Genipin protects the hippocampal neurons from the toxicity of Alzheimer′s amyloid β protein. It has anti-inflammatory and anti-angiogenesis effects. Genipin is involved in drug delivery system.

Biochem/physiol Actions

Genipin stimulates insulin secretion in UCP2-dependent manner (Uncoupling protein 2). Genipin is a protein, collagen, gelatin, and chitosan cross-linker.

Genipin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Genipin manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Genipin 6902-77-8
Price
US $200.00-85.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-04-23
WUHAN FORTUNA CHEMICAL CO., LTD
Product
Genipin 6902-77-8
Price
US $0.00/g
Min. Order
1g
Purity
≥98.0%
Supply Ability
10kg/month
Release date
2021-09-29
Chengdu King-tiger Pharm-chem. Tech. Co., Ltd.
Product
Genipin 6902-77-8
Price
US $75.00-5400.00/KG
Min. Order
10g
Purity
98%
Supply Ability
8kg
Release date
2021-08-27

6902-77-8, GenipinRelated Search:


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  • GENIPIN
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  • GenipinQ: What is Genipin Q: What is the CAS Number of Genipin Q: What is the storage condition of Genipin Q: What are the applications of Genipin
  • Jingping
  • Gardenia Fruit P.E
  • Genipin(AS)
  • 6902-77-8
  • Inhibitors
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  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract