Nodakenin

Product Name: Nodakenin
CAS No.: 495-31-8
Chemical Name: Nodakenin
Synonyms: NODAKENIN;Nodakenin-RM;AliNodakenin;Nodakenin USP/EP/BP;Nodakenin, 10 mM in DMSO;Nodakenin, 98%, from Angelica decursiva (Miq.) Franch. & Sav.;2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)-2-propanyl β-D-glucopyranoside;(R)-2-[1-(β-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one;7H-Furo[3,2-g][1]benzopyran-7-one, 2-[1-(β-D-glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-, (2R)-;(2R)-2-[2-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2,3-dihydrofuro[3,2-g]chromen-7-one
CBNumber: CB01410756
Molecular Formula: C20H24O9
Formula Weight: 408.4
MOL File: 495-31-8.mol

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Nodakenin Property

Melting point:: melting at 216°
alpha: D30 +56.6°
Boiling point:: 657.1±55.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
solubility: Chloroform (Slightly, Sonicated), DMSO (Slightly)
form: Solid
pka: 12.90±0.70(Predicted)
color: Off-White to Pale Beige
Major Application: food and beverages
InChIKey: HXCGUCZXPFBNRD-VPVUCYOBNA-N
SMILES: C([C@@H]1OC2=CC3OC(=O)C=CC=3C=C2C1)(C)(C)O[C@H]1[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O1)O |&1:1,18,19,20,22,24,r|

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Safety

Safety Statements: 24/25
WGK Germany: WGK 3
HS Code: 29389090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 25213
Product name: Nodakenin
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 25213
Product name: Nodakenin
Purity: ≥98%
Packaging: 5mg
Price: $116
Updated: 2024/03/01

Cayman Chemical

Product number: 25213
Product name: Nodakenin
Purity: ≥98%
Packaging: 10mg
Price: $214
Updated: 2024/03/01

Cayman Chemical

Product number: 25213
Product name: Nodakenin
Purity: ≥98%
Packaging: 25mg
Price: $494
Updated: 2024/03/01

Usbiological

Product number: 300683
Product name: Nodakenin
Packaging: 10mg
Price: $390
Updated: 2021/12/16

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Nodakenin Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder, soluble in methanol, derived from the plant Peucedanum purpurogenum and Angelica radix.

Uses

Nodakenin is a compound used for inhibiting influenza virus including Nodakenin and/or Nodakenetin.

Definition

ChEBI: Nodakenin is a furanocoumarin.

Synthesis

1. Rhizome of Qianghuo is extracted with ethanol, concentrated, and acid-hydrolyzed. The hydrolysate is passed through macroporous resin. Elution with ethanol of varying concentrations yields an extract rich in the target.
2. The extract is mixed with silica gel and subjected to silica column chromatography with a petroleum ether-ethyl acetate gradient. The 10:1 fraction is collected and purified by preparative HPLC to obtain nodakenin.

in vivo

Nodakenin (10 mg/kg, p.o.) reverses scopolamine-induced cognitive impairments in the passive avoidance test and the Y-maze test^[1].
Nodakenin (10 mg/kg, p.o.) reduces escape latency during training in the Morris water maze test^[1].

Animal Model:	Male ICR mice
Dosage:	2.5, 5, 10 and 20 mg/kg
Administration:	p.o, single dose
Result:	Reversed in step-through latency induced by scopolamine.

IC 50

AChE

Nodakenin Preparation Products And Raw materials

Raw materials

Preparation Products

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Nodakenin Suppliers

China 205 United States 13 USA 1 Global 219

Wuhan ChemFaces Biochemical Co., Ltd.

Tel: 18607101326 15172504745
Fax: +86-27-84254680
Email: aileen@chemfaces.com
Country: China
ProdList: 6905
Advantage: 55

Chengdu Glip Biotechnology Co., Ltd.

Tel: 028-87075086 18030859262
Email: 2851503756@qq.com
Country: China
ProdList: 1928
Advantage: 58

Sichuan Wei Keqi Biological Technology Co., Ltd.

Tel: 028-81700200 18116577057
Fax: 028-81705658
Email: 3003855609@qq.com
Country: China
ProdList: 7778
Advantage: 56

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Dalian Meilun Biotech Co., Ltd.

Tel: 0411-62910999 13889544652
Email: sales@meilune.com
Country: China
ProdList: 4765
Advantage: 58

ShangHai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847 13636370518
Fax: 021-55068248
Email: shyysw007@163.com
Country: China
ProdList: 4999
Advantage: 60

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
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Email: 800078821@qq.com
Country: China
ProdList: 9718
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Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
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Chengdu Climax Biotech Co., Ltd.

Tel: 028-83311324 1278112614
Fax: 028-83311324
Email: climaxbiotech@gmail.com
Country: China
ProdList: 925
Advantage: 58

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View Lastest Price from Nodakenin manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: Nodakenin 495-31-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2026-01-23

Hebei Fengjia New Material Co., Ltd

Product: Nodakenin 495-31-8
Price: US $8.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2024-08-14

Shanghai Standard Technology Co., Ltd.

Product: Nodakenin 495-31-8
Price: US $0.00/mg
Min. Order: 5mg
Purity: ≥98%(HPLC)
Supply Ability: 10 g
Release date: 2019-11-21

495-31-8, NodakeninRelated Search:

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(R)-2-[1-(β-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one

NODAKENIN

(2R)-2-[2-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2,3-dihydrofuro[3,2-g]chromen-7-one

2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)-2-propanyl β-D-glucopyranoside

Nodakenin, 98%, from Angelica decursiva (Miq.) Franch. & Sav.

AliNodakenin

7H-Furo[3,2-g][1]benzopyran-7-one, 2-[1-(β-D-glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-, (2R)-

Nodakenin USP/EP/BP

(R)-2-(2-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)propan-2-yl)-2,3-dihydro-7H-furo[3,2-g]chromen-7-one

Nodakenin-RM

Nodakenin, 10 mM in DMSO

495-31-8

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

standardized herbal extract