ChemicalBook > CAS DataBase List > (1R)-(-)-(10-Camphorsulfonyl)oxaziridine

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine

Product Name
(1R)-(-)-(10-Camphorsulfonyl)oxaziridine
CAS No.
104372-31-8
Chemical Name
(1R)-(-)-(10-Camphorsulfonyl)oxaziridine
Synonyms
(-)-CAMPHORSULFONYLOXAZIRIDINE;(10-camphorsulfonyl)oxaziridine;R-(10-Camphorsulfonyl)oxaziridine;(R)-2,N-EPOXY-EXO-10,2-BORNANESULTAM;(-)-((CAMPHORYL) SULFONYL)OXAZIRIDINE;(1R)-(-)-(CAMPHORYLSULFONYL)OXAZIRIDINE;(1R)-(-)-(10-Camphorsulfonyl)oxaziridin;(1R)-(-)-(10-CAMPHORSULFONYL)OXAZIRIDINE;(1R)-(-)-2,N-EPOXY-EXO-10,2-BORNANESULTAM;(1R)-(-)-(10-CAMPHORSULPHONYL)OXAZIRIDINE
CBNumber
CB9768000
Molecular Formula
C10H15NO3S
Formula Weight
229.3
MOL File
104372-31-8.mol
More
Less

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine Property

Melting point:
170-174 °C
alpha 
-46.6 º (c=2, CHCl3 25 ºC)
Boiling point:
317.6±25.0 °C(Predicted)
Density 
1.2486 (rough estimate)
refractive index 
1.5060 (estimate)
Flash point:
170℃
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), Methanol (Slightly)
pka
-11.75±0.40(Predicted)
form 
Powder
color 
White
optical activity
[α]20/D 44°, c = 2.2 in chloroform
BRN 
6274369
InChI
InChI=1/C10H15NO3S/c1-8(2)7-3-4-9(8)6-15(12,13)11-10(9,5-7)14-11/h7H,3-6H2,1-2H3/t7-,9-,10?,11?/s3
InChIKey
GBBJBUGPGFNISJ-SENRVMEJNA-N
SMILES
C123C[C@@]4([H])CC[C@@]1(CS(=O)(=O)N2O3)C4(C)C |&1:2,6,r|
CAS DataBase Reference
104372-31-8(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-24/25
WGK Germany 
3
F 
10
HS Code 
29349990
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
349003
Product name
(1R)-(?)-(10-Camphorsulfonyl)oxaziridine
Packaging
1g
Price
$188
Updated
2025/07/31
TCI Chemical
Product number
C1327
Product name
(2S,8aR)-(-)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent]
Purity
>95.0%(T)
Packaging
1g
Price
$27
Updated
2025/07/31
TCI Chemical
Product number
C1327
Product name
(2S,8aR)-(-)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent]
Purity
>95.0%(T)
Packaging
5g
Price
$79
Updated
2025/07/31
TRC
Product number
C175095
Product name
(1R)-(-)-(10-Camphorsulfonyl)oxaziridine
Packaging
50g
Price
$405
Updated
2021/12/16
AK Scientific
Product number
J97606
Product name
(1R)-(-)-(10-Camphorsulfonyl)oxaziridine
Packaging
1g
Price
$20
Updated
2021/12/16
More
Less

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine Chemical Properties,Usage,Production

Chemical Properties

White crystalline powder

Uses

Reactant involved in:

  • Asymmetric synthesis of proton pump inhibitors
  • Asymmetric synthesis of polyhydroxylated pyrrolidines
  • Diastereoselective hydroxylation of chlorophylls a and b enolate anions

Used in impregnated silica nanoparticles for removal of sulfur mustard from wastewater

Used to modify blebbistatin for investigations of myosin inhibitor design

Uses

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine is a useful synthetic intermediate. Used for asymmetric hydroxylation.

Synthesis

The enantiopure (1S)-(+)-(Camphorylsulfonyl)oxaziridine and (1R)-(-)-(10-Camphorsulfonyl)oxaziridine and [(8,8- dichlorocamphor)sulfonyl]oxaziridines (2) are commercially available. They can also be prepared on a large scale via the oxidation of corresponding camphorsulfonimines with buffered Potassium Monoperoxysulfate (Oxone) or buffered peracetic acid. Since oxidation takes place from the endo face of the C=N double bond, only a single oxaziridine isomer is obtained. The precursor camphorsulfonimines can be prepared in 3 steps (>80% yield) from inexpensive (+)- and (-)-10-Camphorsulfonic Acids. A variety of (camphorylsulfonyl)oxaziridine derivatives such as (2)-(4) are also readily available via the functionalization of the camphorsulfonimines followed by oxidation.

Synthesis

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine is a neutral, aprotic, electrophilic, and asymmetric oxidizing agents for the chemoselective oxidation of many nucleophilic substrates such as sulfides, enamines, enol esters, carbanions, and enolates.

References

1. Mergelsberg, I.; Gala, D.; Scherer, D.; DiBenedetto, D.; Tanner TL 1992, 33, 161.
2. Davis, F. A.; Kumar, A.; Chen, B.-C. JOC 1991, 56, 1143.
3. Chen, B.-C.; Weismiller, M. C.; Davis, F. A.; Boschelli, D.; Empfield, J. R.; Smith, III, A. B. T 1991, 47, 173.

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(1R)-(-)-(10-Camphorsulfonyl)oxaziridine Suppliers

Americas 1 Belgium 4 Canada 2 China 180 Europe 3 France 3 Germany 6 India 8 Japan 2 Switzerland 1 The Netherlands 1 United Kingdom 10 United States 31 Global 252
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Beijing Donghualituo Techonlogy Development Co.,Ltd.
Tel
010-88425576
Fax
(+86)-10-88425546
Email
sales@dhltchem.com
Country
China
ProdList
793
Advantage
59
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Country
China
ProdList
18207
Advantage
66
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9310
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11035
Advantage
64
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9883
Advantage
59
Shanghai Harvest Chemical Industrial Co., Ltd.
Tel
021-31038972,31038973 17321035817
Fax
+86-21-51385350
Email
sales@harvest-chem.com
Country
China
ProdList
2816
Advantage
64
Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Chemsky（shanghai）International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
Daicel Chiral Technologies (China)CO.,LTD
Tel
021-50460086-9 15921403865
Fax
+86-21-50462321
Email
han_yajun@dctc.daicel.com
Country
China
ProdList
7471
Advantage
65
Beijing Taiya Jie Technology Development Co., Ltd.
Tel
021-33690831-8001 13552411790
Fax
021-33690831
Email
postmaster@tyjchem.cn
Country
China
ProdList
1542
Advantage
55
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Nanjing Norris-Pharm Technology Co., Ltd
Tel
18652989687
Fax
+86-25-52131256
Email
sales@norris-pharm.com
Country
China
ProdList
8878
Advantage
55
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9546
Advantage
55
Zouping Mingxing Chemical Co.,Ltd.
Tel
86-13605431940 13605431940
Fax
0086-0543-2240079
Email
zpmxchemical@126.com
Country
China
ProdList
1490
Advantage
62
Wuxi Zhangkun Biochemical Technology Co., Ltd.
Tel
+86 0510-85629785
Fax
+86 0510-85625359
Country
China
ProdList
2327
Advantage
58
Bide Pharmatech Ltd.
Tel
400-164-7117 13681763483
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39966
Advantage
60
Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
9476
Advantage
58
Wuxi Zhongkun Biochemical Technology Co., Ltd.
Tel
0510-85629785 18013409632
Fax
051085625359
Email
sales@reading-chemicals.com
Country
China
ProdList
15178
Advantage
58
Wuhan Dahua Pharmaceutical Co., Ltd.
Tel
027-59262863 13277907145 3091977954
Fax
027-59420980
Country
China
ProdList
4942
Advantage
58
Shanghai YuLue Chemical Co., Ltd.
Tel
021-60345187 13671753212
Fax
021-34702061
Email
lzz841106@aliyun.com
Country
China
ProdList
10263
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
0571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
14912
Advantage
59
Shanghai Chang-Gen Chemical Technology Co., Ltd.
Tel
021-69106814 13917161715
Email
3007500651@qq.com
Country
China
ProdList
80
Advantage
60
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5674
Advantage
50
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51395
Advantage
80
Nanjing Endesa Bio-tech Co., Ltd.
Tel
025-58862853 18915922038
Fax
+86-025-58862853
Email
sales@endesachem.com
Country
China
ProdList
591
Advantage
58
CHMA Chemical Technology (Shanghai) Co., Ltd
Tel
021-61556450 15800904410
Fax
021-61556450
Country
China
ProdList
2832
Advantage
58
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
6687
Advantage
55
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3495
Advantage
58
Lanzhou Angeli Biochemical Technology Co., Ltd.
Tel
0931-8235634 13321316780
Fax
+86(931) 4873122
Email
1455540579@qq.com
Country
China
ProdList
958
Advantage
55
Shanghai Xilong Biochemical Technology Co., Ltd.
Tel
021-52907766-8042
Fax
021-52906523
Country
China
ProdList
9941
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
parabiochem
Tel
025-83453382-8005
Fax
025-83453382
Email
sale@parabiochem.com
Country
China
ProdList
9595
Advantage
55
Chengdu Huachun Technology Co., Ltd
Tel
400-1166-196 15982826727
Fax
QQ：800101999
Email
cdhxsj@163.com
Country
China
ProdList
14603
Advantage
60
Grader reagent
Tel
18221735425
Email
sales@xinpingchem.com
Country
China
ProdList
9942
Advantage
58
Shenzhen Simeiquan Biotechnology Co. Ltd
Tel
18126413629 0755-23311925 2355327053
Fax
0755-23311925
Email
abel@ycgmp.com
Country
China
ProdList
5113
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2886750 13927877953
Fax
0751-2886750
Email
3005811397@qq.com
Country
China
ProdList
13305
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Shenzhen Sendi Biological Technology Co., Ltd.
Tel
18124570582 TEL：0755-23574479 2355327139
Fax
0755-23229476 QQ: 2355327139
Email
siliao02@yccreate.com
Country
China
ProdList
6116
Advantage
58
Guangzhou Kafen Biotech Co.,Ltd
Tel
18029243487 2355327168
Fax
020-31121510
Email
gy@yccreate.com
Country
China
ProdList
4749
Advantage
55
More
Less

View Lastest Price from (1R)-(-)-(10-Camphorsulfonyl)oxaziridine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
(1R)-(-)-(10-Camphorsulfonyl)oxaziridine 104372-31-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-02
Aromsyn Co., Ltd.
Product
(1R)-(-)-(10-Camphorsulfonyl)oxaziridine 104372-31-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
kgs
Release date
2023-02-17
Career Henan Chemical Co
Product
(1R)-(-)-(10-Camphorsulfonyl)oxaziridine 104372-31-8
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
20KG
Release date
2018-08-07

104372-31-8, (1R)-(-)-(10-Camphorsulfonyl)oxaziridineRelated Search:

Resin epoxy White camphor oil (1R)-(-)-10-Camphorsulfonic acid 2-Methylcyclohexylamine 2-CYCLOPENTYL-ETHYLAMINE Cyclopentylamine Ethanesulfonamide 3-METHYLCYCLOHEXYLAMINE BORNYLAMINE 2-Ethyl-1-hexanethiol (1S)-(+)-(10-CAMPHORSULFONYL)OXAZIRIDINE,(1S)-(+)-(10-Camphorsulfonyl)oxaziridine (1S)-(+)-2,N-Epoxy-exo-10,2-bornanesultam Camphor DL-Camphor EPOXY 1-PENTANESULFONAMIDE 4-04-00-00045 (Beilstein Handbook Reference) 1-HEXANESULFONAMIDE PROPANE-1-SULFONAMIDE

  • (-)-(2S,8AR)-(CAMPHORSULFONYL)OXAZIRIDINE
  • (2S,8AR)-(-)-(CAMPHORYLSULFONYL)OXAZIRIDINE
  • (1R)-(-)-(10-CAMPHORSULFONYL)OXAZIRIDINE
  • (1R)-(-)-(10-CAMPHORSULPHONYL)OXAZIRIDINE
  • (1R)-(-)-2,N-EPOXY-EXO-10,2-BORNANESULTAM
  • (1R)-(-)-(CAMPHORYLSULFONYL)OXAZIRIDINE
  • (R)-2,N-EPOXY-EXO-10,2-BORNANESULTAM
  • (-)-((CAMPHORYL) SULFONYL)OXAZIRIDINE
  • (2S,8aR)-(-)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent]
  • (-)-CAMPHORSULFONYLOXAZIRIDINE
  • (-)-(2S,8aR)-(Camphorylsulfonyl)oxaziridine, 99+% ee, 99+%
  • 4H-4a,7-Methanooxazirino3,2-i2,1benzisothiazole, tetrahydro-9,9-dimethyl-, 3,3-dioxide, (4aR,7S,8aR)-
  • (2S,8AS)-(-)-(CAMPHORYLSULFONYL)OXAZIRIDINE
  • (2S 8AR)-(-)-(CAMPHORYLSULFONYL)OXAZIRIDINE [ASYMMETRIC OXIDIZING GRADE] 98+%
  • R-(10-Camphorsulfonyl)oxaziridine
  • Tetrahydro-9,9-dimethyl-4H-4a,7-methanooxazirino[3,2-i][2,1]benzisothiazole 3,3-dioxide
  • (10-camphorsulfonyl)oxaziridine
  • (1R)-(-)-(Camphorylsulfonyl)oxaziridine, (1R)-(-)-2,N-Epoxy-exo-10,2-bornanesultam
  • (-)-(2S,8AR)-(Camphorylsulfonyl)oxaziridine, 98%, ee:99+%
  • (-)-(2S,8aR)-(Camphorylsulfonyl)oxaziridine, 99+% ee
  • (-)-(2S,8aR)-(Camphorylsulfonyl)oxaziridine,98+%
  • (4aR,7S,8aR)-Tetrahydro-9,9-diMethyl-4H-4a,7-Methano-1,2-oxazirino[3,2-i]-2,1-benzisothiazole 3,3-Dioxide
  • (1R,2S)-(-)-2,N-Epoxy-10,2-caMphorsultaM, 96%
  • (1R)-(-)-(10-Camphorsulfonyl)oxaziridine 1R)-(-)-(Camphorylsulfonyl)oxaziridine
  • (R)-(10-Camphorsulfonyl)oxaziridine,99%e.e.
  • 7,7-dimethyl-4-(2-oxaziridinylsulfonylmethyl)-3-bicyclo[2.2.1]heptanone
  • (1R)-(-)-(10-Camphorsulfonyl)oxaziridin
  • (2S,8aR)-(-)-(Camphorylsulfonyl)oxaziridine [Asymmetric Oxidizing Reagent]&gt
  • (-)-(2S,8aR)-(Camphorylsulfonyl)oxaziridine
  • 4H-4a,7-Methanooxazirino[3,2-i][2,1]benzisothiazole, tetrahydro-9,9-dimethyl-, 3,3-dioxide, (4aR,7S,8aR)- (9CI, ACI)
  • Tetrahydro-9,9-dimethyl-4H-4a,7-methanooxazirino3,2-i2,1benzisothiazole 3,3-dioxide (4aR,7S,8aR)-
  • 11,11-dimethyl-5-oxa-3-thia-4-azatetracyclo[6.2.1.01,6.04,6]undecane-3,3-dione
  • (1<i>R</i>)-(?)-(10-Camphorsulfonyl)oxaziridine
  • (1R)-(?)-(10-Camphor?sulfonyl)oxaziridine 98+
  • 104372-31-8
  • Oxidation
  • Bicyclic Monoterpenes
  • Terpenes
  • Sulfur Compounds (for Synthesis)
  • Asymmetric Synthesis
  • Chiral Catalysts, Ligands, and Reagents
  • Hydroxylation
  • Biochemistry
  • Oxidation
  • Sulfur Compounds (for Synthesis)
  • Synthetic Organic Chemistry
  • Terpenes
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Asymmetric Synthesis
  • Bicyclic Monoterpenes
  • chiral
  • Chiral Reagents