Methyl 2-amino-3-methylbenzoate
- Product Name
- Methyl 2-amino-3-methylbenzoate
- CAS No.
- 22223-49-0
- Chemical Name
- Methyl 2-amino-3-methylbenzoate
- Synonyms
- Methyl 2-amino-3-met;Methyl 2-Amino-m-toluate;methyl 3-methylanthranilate;Methyl 2-aMino-3-Methylbe...;Methyl 2-mino-3-Methylbenzoate;Methyl 3-methyl-2-aminobenzoate;METHYL 2-AMINO-3-METHYLBENZOATE;Methyl2-Amino-3-methylbenzoate>2-Amino-m-toluic Acid Methyl Ester;Methyl 2-amino-3-methylbenzoate 98%
- CBNumber
- CB9773134
- Molecular Formula
- C9H11NO2
- Formula Weight
- 165.19
- MOL File
- 22223-49-0.mol
Methyl 2-amino-3-methylbenzoate Property
- Melting point:
- 115-117°C
- Boiling point:
- 153℃/23mm
- Density
- 1.132±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 2.05±0.10(Predicted)
- form
- Solid
- color
- Pink
- FreezingPoint
- 25.0 to 29.0 ℃
- CAS DataBase Reference
- 22223-49-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- M2193
- Product name
- Methyl 2-Amino-3-methylbenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
- Product number
- M2193
- Product name
- Methyl 2-Amino-3-methylbenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $165
- Updated
- 2025/07/31
- Product number
- A612155
- Product name
- 2-Amino-3-methylbenzoicAcidMethylEster
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
- Product number
- A612155
- Product name
- 2-Amino-3-methylbenzoicAcidMethylEster
- Packaging
- 50g
- Price
- $250
- Updated
- 2021/12/16
- Product number
- 043125
- Product name
- Methyl 2-amino-3-methylbenzenecarboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $10
- Updated
- 2021/12/16
Methyl 2-amino-3-methylbenzoate Chemical Properties,Usage,Production
Chemical Properties
Pale brown liquid
Uses
2-Amino-3-methylbenzoic Acid Methyl Ester is the methyl ester derivative of 2-Amino-3-methylbenzoic Acid (A612150); a metabolite of Lidocaine (L397800) with potential herbicidal activity. 2-Amino-3-methylbenzoic Acid Methyl Ester is also used as the starting material in the synthesis of N-(2-Methoxyacetate)-N-(2-carboxy-6-methylphenyl)-alanine (M260810); a metabolite of Metalaxyl (M258740) which is an agricultural fungicide.
Synthesis
5471-82-9
22223-49-0
The general steps for synthesizing methyl 2-amino-3-methylbenzoate from methyl 3-methyl-2-nitrobenzoate are as follows: Step A: Preparation of methyl 2-amino-3-methylbenzoate Methyl 3-methyl-2-nitrobenzoate (98.5 g, 505 mmol), 5% Pd/C (Degussa CE 105 XRCAV, 1.0 g) and acetonitrile (300 mL) were mixed in a 600 mL pressure vessel. The mixture was heated to 70°C and hydrogenated at 65 psi (450 kPa) under hydrogen pressure for 8 hours. Subsequently, 5% Pd/C (1.0 g) was added supplementally and hydrogenation was continued for 8.5 hours at 100 psi (690 kPa) hydrogen pressure. Upon completion of the reaction, the reaction mixture was cooled to room temperature, the hydrogen in the reactor was replaced with nitrogen, and then filtered through a Celite diatomaceous earth filter aid. The filter cake was washed with acetonitrile (3 x 25 mL). The combined filtrates were concentrated to about 160 g, and then the total weight was adjusted with acetonitrile to 200 g. The amount of the title compound in solution was measured to be 40.3 wt%, or 80.6 g, in 97.5% yield by quantitative HPLC analysis.
References
[1] Tetrahedron, 2013, vol. 69, # 32, p. 6679 - 6686
[2] Patent: WO2006/62978, 2006, A1. Location in patent: Page/Page column 23
[3] Asian Journal of Chemistry, 2014, vol. 26, # 7, p. 1921 - 1930
[4] Organic and Biomolecular Chemistry, 2014, vol. 12, # 30, p. 5629 - 5633
[5] Chemische Berichte, 1907, vol. 40, p. 4413
Methyl 2-amino-3-methylbenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
Methyl 2-amino-3-methylbenzoate Suppliers
- Tel
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- Fax
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- sales@tcieurope.be
- Country
- Belgium
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View Lastest Price from Methyl 2-amino-3-methylbenzoate manufacturers
- Product
- Methyl 2-amino-3-methylbenzoate 22223-49-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-12
- Product
- Methyl 2-amino-3-methylbenzoate 22223-49-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
- Product
- Methyl 2-amino-3-methylbenzoate 22223-49-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09