ChemicalBook > CAS DataBase List > Methyl 2-amino-3-methylbenzoate
Methyl 2-amino-3-methylbenzoate
- Product Name
- Methyl 2-amino-3-methylbenzoate
- CAS No.
- 22223-49-0
- Chemical Name
- Methyl 2-amino-3-methylbenzoate
- Synonyms
- Methyl 2-amino-3-met;Methyl 2-Amino-m-toluate;methyl 3-methylanthranilate;Methyl 2-aMino-3-Methylbe...;Methyl 2-mino-3-Methylbenzoate;Methyl 3-methyl-2-aminobenzoate;METHYL 2-AMINO-3-METHYLBENZOATE;Methyl2-Amino-3-methylbenzoate>2-Amino-m-toluic Acid Methyl Ester;Methyl 2-amino-3-methylbenzoate 98%
- CBNumber
- CB9773134
- Molecular Formula
- C9H11NO2
- Formula Weight
- 165.19
- MOL File
- 22223-49-0.mol
More
Less
Methyl 2-amino-3-methylbenzoate Property
- Melting point:
- 115-117°C
- Boiling point:
- 153℃/23mm
- Density
- 1.132±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 2.05±0.10(Predicted)
- form
- Solid
- color
- Pink
- FreezingPoint
- 25.0 to 29.0 ℃
- CAS DataBase Reference
- 22223-49-0(CAS DataBase Reference)
More
Less
More
Less
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
More
Less
N-Bromosuccinimide Price
TCI Chemical
- Product number
- M2193
- Product name
- Methyl 2-Amino-3-methylbenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 5g
- Price
- $42
- Updated
- 2025/07/31
TCI Chemical
- Product number
- M2193
- Product name
- Methyl 2-Amino-3-methylbenzoate
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $165
- Updated
- 2025/07/31
TRC
- Product number
- A612155
- Product name
- 2-Amino-3-methylbenzoicAcidMethylEster
- Packaging
- 50g
- Price
- $250
- Updated
- 2021/12/16
TRC
- Product number
- A612155
- Product name
- 2-Amino-3-methylbenzoicAcidMethylEster
- Packaging
- 5g
- Price
- $50
- Updated
- 2021/12/16
Matrix Scientific
- Product number
- 043125
- Product name
- Methyl 2-amino-3-methylbenzenecarboxylate
- Purity
- 95+%
- Packaging
- 25g
- Price
- $41
- Updated
- 2021/12/16
More
Less
Methyl 2-amino-3-methylbenzoate Chemical Properties,Usage,Production
Chemical Properties
Pale brown liquid
Uses
2-Amino-3-methylbenzoic Acid Methyl Ester is the methyl ester derivative of 2-Amino-3-methylbenzoic Acid (A612150); a metabolite of Lidocaine (L397800) with potential herbicidal activity. 2-Amino-3-methylbenzoic Acid Methyl Ester is also used as the starting material in the synthesis of N-(2-Methoxyacetate)-N-(2-carboxy-6-methylphenyl)-alanine (M260810); a metabolite of Metalaxyl (M258740) which is an agricultural fungicide.
Synthesis
5471-82-9
22223-49-0
The general steps for synthesizing methyl 2-amino-3-methylbenzoate from methyl 3-methyl-2-nitrobenzoate are as follows: Step A: Preparation of methyl 2-amino-3-methylbenzoate Methyl 3-methyl-2-nitrobenzoate (98.5 g, 505 mmol), 5% Pd/C (Degussa CE 105 XRCAV, 1.0 g) and acetonitrile (300 mL) were mixed in a 600 mL pressure vessel. The mixture was heated to 70°C and hydrogenated at 65 psi (450 kPa) under hydrogen pressure for 8 hours. Subsequently, 5% Pd/C (1.0 g) was added supplementally and hydrogenation was continued for 8.5 hours at 100 psi (690 kPa) hydrogen pressure. Upon completion of the reaction, the reaction mixture was cooled to room temperature, the hydrogen in the reactor was replaced with nitrogen, and then filtered through a Celite diatomaceous earth filter aid. The filter cake was washed with acetonitrile (3 x 25 mL). The combined filtrates were concentrated to about 160 g, and then the total weight was adjusted with acetonitrile to 200 g. The amount of the title compound in solution was measured to be 40.3 wt%, or 80.6 g, in 97.5% yield by quantitative HPLC analysis.
References
[1] Tetrahedron, 2013, vol. 69, # 32, p. 6679 - 6686
[2] Patent: WO2006/62978, 2006, A1. Location in patent: Page/Page column 23
[3] Asian Journal of Chemistry, 2014, vol. 26, # 7, p. 1921 - 1930
[4] Organic and Biomolecular Chemistry, 2014, vol. 12, # 30, p. 5629 - 5633
[5] Chemische Berichte, 1907, vol. 40, p. 4413
Methyl 2-amino-3-methylbenzoate Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Methyl 2-amino-3-methylbenzoate Suppliers
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 4006356688 18621169109
- Fax
- 86-21-61259102
- market03@meryer.com
- Country
- China
- ProdList
- 40228
- Advantage
- 62
- Tel
- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15838
- Advantage
- 69
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- 0311-89250318 031166536426
- Fax
- 4000311741
- master@sjzsdyn.com
- Country
- China
- ProdList
- 2805
- Advantage
- 65
- Tel
- 86-027-67849912
- Fax
- 86-027-87531808
- sales@chemwish.com
- Country
- China
- ProdList
- 35896
- Advantage
- 56
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 010-010-82967028 13522913783
- Fax
- +86-10-82967029
- 2355560935@qq.com
- Country
- China
- ProdList
- 12000
- Advantage
- 60
- Tel
- 13817811078
- Fax
- 86-021-50426522,50426273
- sales@jingyan-chemical.com
- Country
- China
- ProdList
- 9976
- Advantage
- 60
- Tel
- 0573-85285100 18627885956
- Fax
- 0573-85285100
- isenchem@163.com
- Country
- China
- ProdList
- 9310
- Advantage
- 66
- Tel
- 021-31038972,31038973 17321035817
- Fax
- +86-21-51385350
- sales@harvest-chem.com
- Country
- China
- ProdList
- 2816
- Advantage
- 64
- Tel
- 10-61256048 13810278579
- Fax
- +86 10 61256049
- sales@zeroschem.com
- Country
- China
- ProdList
- 1371
- Advantage
- 59
- Tel
- 025-83697070
- Fax
- +86-25-83453306
- info@chemlin.com.cn
- Country
- China
- ProdList
- 16075
- Advantage
- 64
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 86-0571-85151182
- Fax
- 86-0571-85151182
- Country
- China
- ProdList
- 5691
- Advantage
- 66
- Tel
- 010-82954736 13391601435
- sales@isomersyn.com
- Country
- China
- ProdList
- 3295
- Advantage
- 57
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- 0086-21-58956006
- Fax
- 0086-21-58956100
- Country
- China
- ProdList
- 7811
- Advantage
- 57
- Tel
- +86 (573) 82222445 (0)18006601000 452520369
- Fax
- +86 (573) 82222643
- sales@maya-r.com
- Country
- China
- ProdList
- 11707
- Advantage
- 57
- Tel
- 0370-2785118 17550508557
- Fax
- QQ：3470079902
- 675141927@qq.com
- Country
- China
- ProdList
- 3199
- Advantage
- 55
- Tel
- 021-56491756 13512199871
- Fax
- 021-5649-1756
- 2819742715@qq.com
- Country
- China
- ProdList
- 4000
- Advantage
- 55
- Tel
- 18986259541
- Fax
- 027-87840182
- sales@3stc.com
- Country
- China
- ProdList
- 3764
- Advantage
- 58
- Tel
- 022-58013646 13011382049
- Fax
- 022-23854368
- sales@jinyudachem.com
- Country
- China
- ProdList
- 1930
- Advantage
- 55
- Tel
- 021-58170097
- info@topbiochem.com
- Country
- China
- ProdList
- 9510
- Advantage
- 58
- Tel
- 025-66113011 17798518460
- Fax
- (1)02557626880
- cfzhang@aikonchem.com
- Country
- China
- ProdList
- 19913
- Advantage
- 55
- Tel
- 4009209199
- Fax
- 86-021-52271987
- sales@9dingchem.com
- Country
- China
- ProdList
- 22514
- Advantage
- 55
- Tel
- 0086-22-60330256
- Fax
- 0086-22-60330256
- Country
- China
- ProdList
- 83
- Advantage
- 58
- Tel
- +86-021-50935922
- Fax
- +86-021-33847795
- Country
- China
- ProdList
- 7865
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 400-1166-196 13458535857
- Fax
- QQ：800101999
- cdhxsj@163.com
- Country
- China
- ProdList
- 13350
- Advantage
- 58
- Tel
- 021-60345187 13671753212
- Fax
- 021-34702061
- lzz841106@aliyun.com
- Country
- China
- ProdList
- 10263
- Advantage
- 55
- Tel
- 15221275939
- Fax
- 021-50706099
- shenlinxing@macklin.cn
- Country
- China
- ProdList
- 15873
- Advantage
- 55
- Tel
- 021-64609169 18901607656
- Fax
- 021-64609160
- greensnown@163.com
- Country
- China
- ProdList
- 9906
- Advantage
- 50
- Tel
- 021-69106960 13701823733
- Fax
- 021-69106780
- 13701823733@163.com
- Country
- China
- ProdList
- 4641
- Advantage
- 60
- Tel
- +86-021-61654350
- Fax
- +86-021-61654350
- 1245958370@qq.com
- Country
- China
- ProdList
- 2982
- Advantage
- 50
- Tel
- 010-56218822 13717722232
- Fax
- 010-56218800
- xinsavichem@163.com
- Country
- China
- ProdList
- 3201
- Advantage
- 56
- Tel
- 13718199399
- Fax
- QQ : 206661479
- holiyangchem@163.com
- Country
- China
- ProdList
- 3280
- Advantage
- 56
- Tel
- 021-69005955 13701776567
- Fax
- 021-69005775
- youpengchem@163.com
- Country
- China
- ProdList
- 4161
- Advantage
- 56
- Tel
- 13708085536 13708085536
- Fax
- QQ : 121102042
- hanovichem@163.com
- Country
- China
- ProdList
- 3282
- Advantage
- 56
- Tel
- 021-021-69182866 13701855675
- Fax
- 021-69182022
- tongyuanchem@126.com
- Country
- China
- ProdList
- 4193
- Advantage
- 58
- Tel
- 021-33516722 13701817765
- Fax
- 021-33516776
- kaisaichem@163.com
- Country
- China
- ProdList
- 4610
- Advantage
- 58
- Tel
- 13716033033
- Fax
- 010-56276266
- hanchochem@163.com
- Country
- China
- ProdList
- 2960
- Advantage
- 50
- Tel
- 021-69515658 ; 69515628 13701998368
- Fax
- 021-69515998
- longrunchem@163.com
- Country
- China
- ProdList
- 3786
- Advantage
- 50
- Tel
- 021-69992220 13701886816
- Fax
- 021-69992237
- roleadchem@163.com
- Country
- China
- ProdList
- 4613
- Advantage
- 50
- Tel
- 021-69185552 13701777608
- Fax
- 021-69186006
- kangtuochem@163.com
- Country
- China
- ProdList
- 4232
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- Fax
- -
- eric_feng1954@126.com
- Country
- China
- ProdList
- 9248
- Advantage
- 55
- Tel
- 028-64353063
- Fax
- 028-64353063 QQ:784253935
- reacchemical@163.com
- Country
- China
- ProdList
- 5253
- Advantage
- 58
More
Less
View Lastest Price from Methyl 2-amino-3-methylbenzoate manufacturers
Shaanxi Dideu New Materials Co. Ltd
- Product
- Methyl 2-amino-3-methylbenzoate 22223-49-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98.0%
- Supply Ability
- 10000KGS
- Release date
- 2025-05-12
Hebei Chuanghai Biotechnology Co., Ltd
- Product
- Methyl 2-amino-3-methylbenzoate 22223-49-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
Henan Aochuang Chemical Co.,Ltd.
- Product
- Methyl 2-amino-3-methylbenzoate 22223-49-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-10-09
22223-49-0, Methyl 2-amino-3-methylbenzoateRelated Search:
Methyl 3-methyl-2-nitrobenzoate
Methyl acetate
6-Aminocaproic acid
METSULFURON METHYL
3-Methylanthranilic acid
4-Dimethylaminobenzoic acid
Glycine
Methyl benzoate
Methyl acrylate
Methylparaben
4-Aminobenzoic acid
Bensulfuron methyl
Methyl 2-iodobenzoate
Methyl anthranilate
Kresoxim-methyl
Thiophanate-methyl
Methyl
METHYL 3-AMINO-4-METHYLBENZOATE,Methyl 3-amino-4-methylbenzoate 98%