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METHYL 2-CHLOROISONICOTINATE

Product Name
METHYL 2-CHLOROISONICOTINATE
CAS No.
58481-11-1
Chemical Name
METHYL 2-CHLOROISONICOTINATE
Synonyms
BUTTPARK 91\04-05;METHYL 2-CHLOROISONICOTINATE;Methyl 2-chloroisonicotin...;. methyl-2-chloroisonicotiate;Methyl2-Chloroisonicotinate>3-chloro-4-iodo-2-methylbenzoate;Methyl 2-chloroisonicotinate ,98%;Methyl 2-chloropyidine-4-carboxylate;METHYL 2-CHLORO-4-PYRIDINECARBOXYLATE;METHYL 2-CHLOROPYRIDINE-4-CARBOXYLATE
CBNumber
CB9777334
Molecular Formula
C7H6ClNO2
Formula Weight
171.58
MOL File
58481-11-1.mol
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METHYL 2-CHLOROISONICOTINATE Property

Melting point:
32-36 °C
Boiling point:
70°C/0.1mmHg(lit.)
Density 
1.294±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
Inert atmosphere,2-8°C
pka
-1.15±0.10(Predicted)
form 
powder to lump to clear liquid
color 
White or Colorless to Yellow
CAS DataBase Reference
58481-11-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
37/38-41
Safety Statements 
26-36/39
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29333990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
660604
Product name
Methyl 2-chloropyridine-4-carboxylate
Purity
97%
Packaging
5g
Price
$60.6
Updated
2023/06/20
TCI Chemical
Product number
M2164
Product name
Methyl 2-Chloroisonicotinate
Purity
>98.0%(GC)
Packaging
5g
Price
$18
Updated
2025/07/31
TCI Chemical
Product number
M2164
Product name
Methyl 2-Chloroisonicotinate
Purity
>98.0%(GC)
Packaging
25g
Price
$69
Updated
2025/07/31
TRC
Product number
M295658
Product name
Methyl 2-Chloroisonicotinate
Packaging
5g
Price
$75
Updated
2021/12/16
TRC
Product number
M295658
Product name
Methyl 2-Chloroisonicotinate
Packaging
2.5g
Price
$65
Updated
2021/12/16
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METHYL 2-CHLOROISONICOTINATE Chemical Properties,Usage,Production

Chemical Properties

White to light brown solid

Synthesis

67-56-1

6313-54-8

58481-11-1

2-Chloroisonicotinic acid (5.10 g, 32.38 mmol) was dissolved in methanol (150 mL) and thionyl chloride (12 mL) was added slowly. The reaction mixture was stirred at 70 °C for 5 h. After completion of the reaction, the reaction solution was concentrated under reduced pressure by rotary evaporator. The concentrated residue was dissolved in dichloromethane (250 mL), washed sequentially with 10% aqueous potassium carbonate (2×150 mL), dried over anhydrous magnesium sulfate, filtered, and the filtrate was concentrated by rotary evaporation to afford methyl 2-chloropyridine-4-carboxylate (SLA 07150) as a yellow solid (5.06 g, 91% yield).The molecular weight of SRA 07150 was 171.58; melting point was 33.0 °C; thin layer chromatography (TLC) Rf value was 0.80 (unfolding reagent ratio methanol:dichloromethane=10:90).1H-NMR (CDCl3, δ): 3.98 (s, 3H, CH3), 7.78 (dd, 1H, J=5.1 Hz, J=1.3 Hz, ArH), 7.89 (d, 1H, J= 0.6 Hz, ArH), 8.55 (dd, 1H, J=5.1 Hz, J=0.6 Hz, ArH).

References

[1] Patent: WO2008/11478, 2008, A2. Location in patent: Page/Page column 76
[2] Patent: WO2016/154241, 2016, A1. Location in patent: Paragraph 578; 579
[3] Patent: US2008/167321, 2008, A1. Location in patent: Page/Page column 14
[4] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988, p. 2785 - 2790
[5] Patent: EP1754706, 2007, A1. Location in patent: Page/Page column 76

METHYL 2-CHLOROISONICOTINATE Preparation Products And Raw materials

Raw materials

Toluene 2-Chloro-4-pyridinecarboxylic acid Methanol Sodium hydroxide Thionyl chloride

Preparation Products

2-Chloroisonicotinaldehyde
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METHYL 2-CHLOROISONICOTINATE Suppliers

Americas 1 China 163 Europe 1 France 1 Germany 3 India 15 Japan 1 Switzerland 2 Ukraine 1 United Kingdom 9 United States 22 Global 219
Apollo Scientific Ltd.
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Email
sales@apolloscientific.co.uk
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United Kingdom
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Key Organics Limited/Bionet Research
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enquiries@keyorganics.ltd.uk
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United Kingdom
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6663
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50
MOLEKULA Ltd.
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kevinbanks@molekula.com
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United Kingdom
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6140
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66
Manchester Organics
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info@manchesterorganics.com
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United Kingdom
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6834
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Eurolabs Limited
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United Kingdom
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6309
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Atlantic Research Chemicals Ltd.
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United Kingdom
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5618
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Fluorochem Ltd
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vernam@fluorochem.co.uk
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United Kingdom
ProdList
6375
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Fluorochem Ltd.
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enquiries@fluorochem.co.uk
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United Kingdom
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Butt Park Ltd.
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113707.50@compuserve.com
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United Kingdom
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View Lastest Price from METHYL 2-CHLOROISONICOTINATE manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD
Product
Methyl 2-chloroisonicotinate 58481-11-1
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
500KGS
Release date
2021-07-14
Hebei Zhanyao Biotechnology Co. Ltd
Product
METHYL 2-CHLOROISONICOTINATE 58481-11-1
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2021-10-15
Dideu Industries Group Limited
Product
METHYL 2-CHLOROISONICOTINATE 58481-11-1
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-22

58481-11-1, METHYL 2-CHLOROISONICOTINATERelated Search:

ETHYL 2-CHLORO-3-CYANO-6-METHYLISONICOTINATE METHYL 2,6-DICHLOROISONICOTINATE ETHYL 6-(TERT-BUTYL)-2-CHLORO-3-CYANOISONICOTINATE METHYL 2-CHLORO-6-METHOXYPYRIDINE-4-CARBOXYLATE ETHYL 2-CHLORO-3-CYANO-6-METHYL-5-NITROPYRIDINE-4-CARBOXYLATE Ethyl 2,6-dichloroisonicotinate METHYL 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLATE Methyl 3-chloroisonicotinate 2-CHLORO-4-FLUOROPHENYL 2,6-DICHLOROISONICOTINATE 2-ACETYLPHENYL 2,6-DICHLOROISONICOTINATE 3,5-DICHLOROPHENYL 2-CHLOROISONICOTINATE [3-(2,6-DICHLOROPHENYL)-5-METHYLISOXAZOL-4-YL]METHYL 2,6-DICHLOROISONICOTINATE 4-(CYANOMETHYL)PHENYL 2,6-DICHLOROISONICOTINATE 3,5-DICHLOROBENZYL 2,6-DICHLOROISONICOTINATE PHENYL 2-CHLOROISONICOTINATE 4-(1,2,3-THIADIAZOL-4-YL)PHENYL 2,6-DICHLOROISONICOTINATE (2,6-DICHLORO-4-PYRIDYL)METHYL 2,6-DICHLOROISONICOTINATE 4-(CYANOMETHYL)PHENYL 2-CHLORO-6-METHOXYISONICOTINATE

  • 2-CHLORO-ISONICOTINIC ACID METHYL ESTER
  • Methyl 2-chloroisonicotinate ,98%
  • 4-Pyridinecarboxylic acid, 2-chloro-, methyl ester
  • BUTTPARK 91\04-05
  • METHYL 2-CHLOROISONICOTINATE
  • METHYL 2-CHLOROPYRIDINE-4-CARBOXYLATE
  • METHYL 2-CHLORO-4-PYRIDINECARBOXYLATE
  • Methyl 2-chloroisonicotin...
  • 2-Chloroisonicotinic Acid Methyl Ester Methyl 2-Chloro-4-pyridinecarboxylate 2-Chloro-4-pyridinecarboxylic Acid Methyl Ester
  • Methyl 2-chloropyridine-4-carboxylate, 2-Chloro-4-(methoxycarbonyl)pyridine
  • Methyl 2-Chloropyridine-4-carboxylate, 97+%
  • 2-chloro-4-pyridinecarboxylic acid methyl ester
  • 3-chloro-4-iodo-2-methylbenzoate
  • 2-Chloropyridine-4-carboxylic acid methyl ester
  • Methyl2-Chloroisonicotinate&gt
  • METHYL 2-CHLOROISONICOTINATE ISO 9001：2015 REACH
  • . methyl-2-chloroisonicotiate
  • Methyl-2-chloropyridine-4-carboxylate (Methyl 2-chloroisonicotinate)
  • Methyl 2-chloropyidine-4-carboxylate
  • 58481-11-1
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Pyridines
  • Building Blocks
  • alkyl chloride|carboxylic ester
  • Picolinic acid series
  • blocks
  • Carboxes
  • Pyridines
  • Esters
  • Pyridine