2-Chloro-4-pyridinecarboxylic acid
- Product Name
- 2-Chloro-4-pyridinecarboxylic acid
- CAS No.
- 6313-54-8
- Chemical Name
- 2-Chloro-4-pyridinecarboxylic acid
- Synonyms
- 2-CHLOROISONICOTINIC ACID;2-CHLOROPYRIDINE-4-CARBOXYLIC ACID;NSC 40139;BUTTPARK 43\57-03;RARECHEM AL BO 0840;TIMTEC-BB SBB004003;2-Chloroisonicotinic;2-Chloro-4-pyridinec;ChloroisonicotinicAcid;oropyridine-4-carboxyL
- CBNumber
- CB4375001
- Molecular Formula
- C6H4ClNO2
- Formula Weight
- 157.55
- MOL File
- 6313-54-8.mol
2-Chloro-4-pyridinecarboxylic acid Property
- Melting point:
- 246 °C (dec.)(lit.)
- Boiling point:
- 417.7±25.0 °C(Predicted)
- Density
- 1.470±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO, Methanol
- pka
- 3.00±0.10(Predicted)
- form
- Crystalline Powder
- color
- White to beige
- BRN
- 115861
- InChI
- InChI=1S/C6H4ClNO2/c7-5-3-4(6(9)10)1-2-8-5/h1-3H,(H,9,10)
- InChIKey
- QXCOHSRHFCHCHN-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=CC(C(O)=O)=C1
- CAS DataBase Reference
- 6313-54-8(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36-36/37/39
- RIDADR
- UN2811
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 543918
- Product name
- 2-Chloropyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 5g
- Price
- $28.1
- Updated
- 2025/07/31
- Product number
- 543918
- Product name
- 2-Chloropyridine-4-carboxylic acid
- Purity
- 97%
- Packaging
- 25g
- Price
- $101
- Updated
- 2023/06/20
- Product number
- C1368
- Product name
- 2-Chloroisonicotinic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $39
- Updated
- 2025/07/31
- Product number
- C1368
- Product name
- 2-Chloroisonicotinic Acid
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $118
- Updated
- 2025/07/31
- Product number
- C367375
- Product name
- 2-Chloroisonicotinic Acid
- Packaging
- 1g
- Price
- $45
- Updated
- 2021/12/16
2-Chloro-4-pyridinecarboxylic acid Chemical Properties,Usage,Production
Chemical Properties
white crystall powder
Uses
Used in monocomposite films.
Synthesis
33252-30-1
6313-54-8
General procedure for the synthesis of 2-chloroisonicotinic acid from 2-chloro-4-cyanopyridine: 2-chloro-4-cyanopyridine (2 mmol) was dissolved in 5 ml of [bmim]HSO4, and the reaction mixture was heated for 1-3 hours at 60-65 °C. The reaction process was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the reaction mixture was poured into water containing crushed ice and the product precipitated as a precipitate. The precipitate was collected by filtration and dried. High yields (>90%) of 2-chloroisonicotinic acid were obtained in all reactions, and the products were sufficiently pure to require no further purification. The filtrate was concentrated under vacuum, washed twice with diethyl ether and concentrated again under high vacuum. After drying under reduced pressure, about 95% of the ionic liquid was recovered and compared to the original ionic liquid to verify its purity. The recovered ionic liquid showed no significant difference in efficiency of converting nitrile to acid compared to the original ionic liquid and could be reused 5-6 times without significant reduction in activity.
References
[1] Tetrahedron Letters, 2014, vol. 55, # 28, p. 3802 - 3804
[2] Roczniki Chemii, 1955, vol. 29, p. 1019,1025
[3] Chem.Abstr., 1956, p. 12045
2-Chloro-4-pyridinecarboxylic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-Chloro-4-pyridinecarboxylic acid manufacturers
- Product
- 2-Chloro-4-pyridinecarboxylic acid 6313-54-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-20
- Product
- 2-Chloro-4-pyridinecarboxylic acid 6313-54-8
- Price
- US $10.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 ton
- Release date
- 2024-12-17
- Product
- 2-Chloro-4-pyridinecarboxylic acid 6313-54-8
- Price
- US $34.00-1.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-04-03