ChemicalBook > CAS DataBase List > 2-Pyrazinylmethanol

2-Pyrazinylmethanol

Product Name
2-Pyrazinylmethanol
CAS No.
6705-33-5
Chemical Name
2-Pyrazinylmethanol
Synonyms
pyrazinemethanol;Pyrazin-2-ylMeth;pyrazin-2-ylmethal;2-PYRAZINYLMETHANOL;Pyrazin-2-ylmethanol;2-Pyrazinemethanol>2-HYDROXYMETHYLPYRAZINE;(Pyrazin-2-yl)methanol 97%;2-(Hydroxymethyl)pyrazine 97%;2-(Hydroxymethyl)pyrazine, tech
CBNumber
CB9784189
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
6705-33-5.mol
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2-Pyrazinylmethanol Property

Melting point:
38.5
Boiling point:
60°C/0.2mmHg(lit.)
Density 
1.227±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
form 
powder to lump
pka
13.48±0.10(Predicted)
color 
White to Light yellow
λmax
265nm(EtOH)(lit.)
LogP
-0.181 (est)
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
36/37/38-41-37/38-22
Safety Statements 
26-36/37/39-24/25-39
RTECS 
UQ3625000
Hazard Note 
Irritant
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
P2129
Product name
2-Pyrazinemethanol
Purity
>98.0%(GC)
Packaging
1g
Price
$115
Updated
2025/07/31
TRC
Product number
B525018
Product name
2-Pyrazinylmethanol
Packaging
50mg
Price
$60
Updated
2021/12/16
Matrix Scientific
Product number
068527
Product name
2-Pyrazinemethanol
Purity
95+%
Packaging
5g
Price
$69
Updated
2021/12/16
Apolloscientific
Product number
OR12341
Product name
2-(Hydroxymethyl)pyrazine
Purity
tech
Packaging
250mg
Price
$18
Updated
2021/12/16
Matrix Scientific
Product number
068527
Product name
2-Pyrazinemethanol
Purity
95+%
Packaging
1g
Price
$20
Updated
2021/12/16
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2-Pyrazinylmethanol Chemical Properties,Usage,Production

Synthesis

6164-79-0

6705-33-5

The general procedure for the synthesis of 2-hydroxymethylpyrazine from methyl pyrazine-2-carboxylate was as follows: methyl pyrazine-2-carboxylate (8.5 g) was dissolved in water (200 mL), sodium borohydride (11.65 g) was added, and the reaction mixture was stirred. A vigorous exothermic phenomenon was observed during the addition. After continuing to stir vigorously for 30 minutes, ethanol (80 mL) and saturated potassium carbonate solution (150 mL) were added sequentially. The mixture was continued to be stirred for 30 minutes and subsequently extracted with ethyl acetate (5 x 150 mL) and dichloromethane (5 x 150 mL). The organic phases were combined, dried and concentrated to give pyrazin-2-ylmethanol as a yellow oil (5.43 g, 80% yield), which could be used in the next reaction without further purification. The NMR hydrogen spectrum (DMSO-D6) data of the product were as follows: δ 4.65 (s, 2H), 5.57 (br s, 1H), 8.54 (d, 2H), 8.71 (s, 1H).

References

[1] Journal of Organic Chemistry, 2018, vol. 83, # 3, p. 1431 - 1440
[2] Patent: WO2004/93880, 2004, A1. Location in patent: Page/Page column 86
[3] Patent: WO2017/214359, 2017, A1. Location in patent: Page/Page column 73
[4] Synthetic Communications, 2005, vol. 35, # 24, p. 3187 - 3190
[5] Patent: US2011/237584, 2011, A1. Location in patent: Page/Page column 132

2-Pyrazinylmethanol Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Pyrazinylmethanol Suppliers

Belgium 1 China 114 Germany 2 India 2 Japan 1 United Kingdom 3 United States 18 Global 141
J & K SCIENTIFIC LTD.
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View Lastest Price from 2-Pyrazinylmethanol manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
2-Pyrazinylmethanol 6705-33-5
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
800 tons
Release date
2020-04-29
Career Henan Chemical Co
Product
2-Pyrazinylmethanol 6705-33-5
Price
US $1.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
150KG
Release date
2019-07-01

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