Isovaleryl chloride Property

Boiling point:

115-117 °C (lit.)

Density 

0.989 g/mL at 25 °C (lit.)

vapor pressure 

20.3hPa at 20℃

refractive index 

n20/D 1.416(lit.)

Flash point:

66 °F

storage temp. 

Flammables area

solubility 

Chloroform (Soluble), Methanol (Slightly)

form 

Liquid

color 

Clear colorless to slightly yellow or pink

Water Solubility 

decomposes

Sensitive 

Moisture Sensitive

Merck 

14,5232

BRN 

741910

Stability:

Moisture Sensitive

CAS DataBase Reference

108-12-3(CAS DataBase Reference)

NIST Chemistry Reference

Butanoyl chloride, 3-methyl-(108-12-3)

EPA Substance Registry System

Butanoyl chloride, 3-methyl- (108-12-3)

Safety

Hazard Codes 

C,F

Risk Statements 

10-34-37-11-20

Safety Statements 

26-36/37/39-45-9-23-16

RIDADR 

UN 2502 8/PG 2

WGK Germany 

3

F 

21

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29159080

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H314Causes severe skin burns and eye damage

H331Toxic if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Isovaleryl chloride Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS TO SLIGHTLY YELLOW OR PINK LIQUID

Uses

Isovaleryl chloride was used in the synthesis of:

• furanodictines A and B
• tetrapeptide amide, S-benzyl-L-cysteinyl-L-prolyl-L-leucylglycinamide
• (+)-blastmycinone
• (R)- and (S)-2-methyl-4-octanol, aggregation pheromone of some sugarcane weevils

Synthesis Reference(s)

Journal of the American Chemical Society, 69, p. 2917, 1947 DOI: 10.1021/ja01203a514

Flammability and Explosibility

Highly flammable