2-Chloro-4-nitrotoluene Property

Melting point:

61 °C

Boiling point:

260 °C

Density 

1.3246 (rough estimate)

refractive index 

1.5470 (estimate)

Flash point:

150 °C

storage temp. 

Sealed in dry,Room Temperature

solubility 

acetonitrile: soluble

color 

Pale Yellow

Water Solubility 

49 mg/L (20 ºC)

BRN 

1817924

CAS DataBase Reference

121-86-8(CAS DataBase Reference)

NIST Chemistry Reference

Benzene, 2-chloro-1-methyl-4-nitro-(121-86-8)

EPA Substance Registry System

2-Chloro-4-nitrotoluene (121-86-8)

Safety

Hazard Codes 

Xn,N

Risk Statements 

22-36/37/38-20/21/22-52/53

Safety Statements 

36/37/39-26-61

RIDADR 

UN 3457 6.1/PG 3

WGK Germany 

2

RTECS 

XS9100000

TSCA 

Yes

HazardClass 

6.1

PackingGroup 

III

HS Code 

29049090

Hazardous Substances Data

121-86-8(Hazardous Substances Data)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H320Causes eye irritation

H401Toxic to aquatic life

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

2-Chloro-4-nitrotoluene Chemical Properties,Usage,Production

Chemical Properties

LIGHT YELLOW CRYSTALLINE POWDER

Uses

2-Chloro-4-nitrotoluene is a substituted toluene used in the preparation of wide range of compounds such as herbicides, analgesics and

Definition

ChEBI: 2-chloro-4-nitrotoluene is a nitrotoluene that is p-nitrotoluene in which one of the hydrogens that is ortho to the methyl group has been replaced by a chlorine. A pale yellow crystalline compound that is insoluble in water but dissolves in most organic solvents, it is used in the manufacture of dyes. It is a member of monochlorobenzenes and a nitrotoluene.

Production Methods

Chlorination of 4-nitrotoluene at 50 ℃ in the presence of iron(III) chloride catalyst gives good conversion to 2-chloro-4-nitrotoluene, the most readily obtained of all the chloronitrotoluene isomers.

Synthesis Reference(s)

Journal of the American Chemical Society, 104, p. 4680, 1982 DOI: 10.1021/ja00381a032

Safety Profile

A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx and Cl-.