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2-Aminobenzenesulfonamide

Product Name
2-Aminobenzenesulfonamide
CAS No.
3306-62-5
Chemical Name
2-Aminobenzenesulfonamide
Synonyms
orthanilamide;o-sulfanilamide;2-Sulphamoylaniline;2-Aminobenzenesulfamide;2-Amino-benzenesulfomide;2-Aminobenzenesulfonamde;2-amino-benzenesulfonamid;o-aminobenzenesulfonamide;o-amino-benzenesulfonamid;2-AMINOBENZENESULFONAMIDE
CBNumber
CB9853506
Molecular Formula
C6H8N2O2S
Formula Weight
172.2
MOL File
3306-62-5.mol
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2-Aminobenzenesulfonamide Property

Melting point:
155-157 °C(lit.)
Boiling point:
392.7±44.0 °C(Predicted)
Density 
1.3250 (rough estimate)
refractive index 
1.6490 (estimate)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
solubility 
DMSO (Sparingly), Methanol (Slightly)
pka
10.29±0.60(Predicted)
form 
Solid
color 
Off-White to Beige
Water Solubility 
6.655g/L(24 ºC)
InChI
InChI=1S/C6H8N2O2S/c7-5-3-1-2-4-6(5)11(8,9)10/h1-4H,7H2,(H2,8,9,10)
InChIKey
YAZSBRQTAHVVGE-UHFFFAOYSA-N
SMILES
C1(S(N)(=O)=O)=CC=CC=C1N
CAS DataBase Reference
3306-62-5(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
36/37/39-26-22-36
WGK Germany 
3
RTECS 
DA9449000
Hazard Note 
Irritant
HS Code 
29350090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
245887
Product name
2-Aminobenzenesulfonamide
Purity
98%
Packaging
5g
Price
$53.9
Updated
2025/07/31
Sigma-Aldrich
Product number
245887
Product name
2-Aminobenzenesulfonamide
Purity
98%
Packaging
25g
Price
$218
Updated
2023/06/20
TRC
Product number
B401505
Product name
2-Aminobenzenesulfonamide
Packaging
100mg
Price
$70
Updated
2021/12/16
Apolloscientific
Product number
OR27532
Product name
2-Aminobenzenesulphonamide
Purity
98%
Packaging
1g
Price
$15
Updated
2021/12/16
SynQuest Laboratories
Product number
8669-1-X3
Product name
2-Aminobenzenesulfonamide
Packaging
1g
Price
$20
Updated
2021/12/16
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2-Aminobenzenesulfonamide Chemical Properties,Usage,Production

Chemical Properties

white to pale cream crystalline powder or crystals

Uses

Diuretic;Inhibitor of carbonic anhydrase B

Definition

ChEBI: 2-aminobenzenesulfonamide is a sulfonamide and a member of benzenes.

Synthesis

5455-59-4

3306-62-5

General procedure for the synthesis of o-aminobenzenesulfonamide from 2-nitrobenzenesulfonamide: 2-nitrobenzenesulfonamide (80.0 g, 0.58 mol) was dissolved in methanol in the presence of a Pd/C catalyst (10.0 g, 13% w/w) to prepare a solution with a mass concentration of 10%. The hydrogenation reaction was carried out at 50 psi hydrogen pressure and 60°C and the reaction was continued overnight. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to give 60 g of off-white solid o-aminobenzenesulfonamide in 95% yield.

IC 50

CA Ⅸ

Solubility in organics

2-Aminobenzenesulfonamide is freely soluble in water, glacial acetic acid, ethyl alcohol, acetone, and methanol; insoluble in benzene.

References

[1] Patent: CN104761514, 2016, B. Location in patent: Paragraph 0028-0030
[2] Tetrahedron Letters, 2001, vol. 42, # 33, p. 5601 - 5603
[3] Bioorganic and Medicinal Chemistry, 2012, vol. 20, # 7, p. 2455 - 2478
[4] Bioorganic and Medicinal Chemistry, 2013, vol. 21, # 17, p. 5647 - 5647
[5] Bihang till Svenska Vet.-Akad. Handlingar, vol. 27, p. II, No. 1, S. 4

2-Aminobenzenesulfonamide Preparation Products And Raw materials

Raw materials

Iron filings Hydrazinium hydroxide solution Ethanol Palladium 2-Nitrobenzenesulfonamide

Preparation Products

N,N'-DIACETYLSULFANILAMIDE
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2-Aminobenzenesulfonamide Suppliers

Belgium 2 Canada 1 China 163 Europe 2 Germany 4 India 4 South Korea 1 Switzerland 3 The Netherlands 1 Ukraine 2 United Kingdom 15 United States 37 Global 235
CHEMSTEP
Tel
--
Fax
--
Email
info@chemstep.com
Country
Europe
ProdList
6143
Advantage
51
Nantong Chem-Tech.(Group) Co., Ltd
Tel
--
Fax
--
Email
ni.trade@pub.nt.jsinfo.net
Country
Europe
ProdList
1811
Advantage
56
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View Lastest Price from 2-Aminobenzenesulfonamide manufacturers

Hebei Chuanghai Biotechnology Co., Ltd
Product
2-Aminobenzenesulfonamide 3306-62-5
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-28
Career Henan Chemical Co
Product
2-Aminobenzenesulfonamide 3306-62-5
Price
US $522.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1T
Release date
2018-07-23

3306-62-5, 2-AminobenzenesulfonamideRelated Search:

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