2-Fluoroadenine
- Product Name
- 2-Fluoroadenine
- CAS No.
- 700-49-2
- Chemical Name
- 2-Fluoroadenine
- Synonyms
- 2-Fluoro-9H-purin-6-amine;2-fluoro-7H-purin-6-aMine;2-fad;nsc27364;uoroadenine;TCMDC-124283;2-fluoro-adenin;2-FLUOROADENINE;BUTTPARK 25\01-01;2-Fluoroadenine>
- CBNumber
- CB9854134
- Molecular Formula
- C5H4FN5
- Formula Weight
- 153.12
- MOL File
- 700-49-2.mol
2-Fluoroadenine Property
- Melting point:
- >350 °C(lit.)
- Boiling point:
- 239.6±50.0 °C(Predicted)
- Density
- 2.05±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Sparingly, Sonicated, Heated), Methanol (Slightly, Heated)
- form
- Solid
- pka
- 6.84±0.20(Predicted)
- color
- White to Light Yellow
- CAS DataBase Reference
- 700-49-2(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-22
- Safety Statements
- 26-36
- WGK Germany
- 3
- RTECS
- AU6264700
- Hazard Note
- Irritant
- HazardClass
- IRRITANT, IRRITANT-HARMFUL
- HS Code
- 29335990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 535087
- Product name
- 2-Fluoroadenine
- Purity
- 96%
- Packaging
- 1g
- Price
- $146
- Updated
- 2024/03/01
- Product number
- F0647
- Product name
- 2-Fluoroadenine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 200mg
- Price
- $18
- Updated
- 2024/03/01
- Product number
- F0647
- Product name
- 2-Fluoroadenine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $72
- Updated
- 2024/03/01
- Product number
- 30421
- Product name
- 2-Fluoroadenine
- Packaging
- 500mg
- Price
- $68
- Updated
- 2024/03/01
- Product number
- 30421
- Product name
- 2-Fluoroadenine
- Packaging
- 1g
- Price
- $115
- Updated
- 2024/03/01
2-Fluoroadenine Chemical Properties,Usage,Production
Description
2-Fluoroadenine is a purine nucleoside analog which has been investigated for suicide gene therapy for human malignancy. It has been used in the synthesis of heat shock protein 90 (Hsp90) inhibitors that have anticancer activity in vitro. It is also cytotoxic to CEM human leukemia cells with an IC50 value of 0.15 μM.
Chemical Properties
white to light yellow crystal powder
Uses
A purine nucleoside phosphorylase gene therapy for human malignancy.
Uses
2-Fluoroadenine is a fluorinated heterocyclic 2-ring compound. It is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies. 2-Fluoroadenine has been used as an intermediate for antineoplastic drugs such as fludarabine. fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia.
Definition
ChEBI: 2-fluoroadenine is an organofluorine compound that is adenine in which the hydrogen at position 2 (the carbon between the two nitrogens of the pyrimidine ring) is replaced by a fluorine. It has a role as an antineoplastic agent. It is an organofluorine compound and a member of purines.
2-Fluoroadenine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Fluoroadenine Suppliers
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View Lastest Price from 2-Fluoroadenine manufacturers
- Product
- TCMDC-124283 700-49-2
- Price
- US $122.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2024-01-11
- Product
- 2-Fluoroadenine 700-49-2
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000kg/month
- Release date
- 2021-11-25
- Product
- 2-Fluoroadenine 700-49-2
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-22