2-Fluoroadenine

Product Name: 2-Fluoroadenine
CAS No.: 700-49-2
Chemical Name: 2-Fluoroadenine
Synonyms: 2-Fluoro-9H-purin-6-amine;2-fluoro-7H-purin-6-aMine;2-fad;nsc27364;uoroadenine;TCMDC-124283;2-fluoro-adenin;2-FLUOROADENINE;BUTTPARK 25\01-01;2-Fluoroadenine>
CBNumber: CB9854134
Molecular Formula: C5H4FN5
Formula Weight: 153.12
MOL File: 700-49-2.mol

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2-Fluoroadenine Property

Melting point:: >350 °C(lit.)
Boiling point:: 239.6±50.0 °C(Predicted)
Density: 2.05±0.1 g/cm3(Predicted)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: DMSO (Sparingly, Sonicated, Heated), Methanol (Slightly, Heated)
form: Solid
pka: 6.84±0.20(Predicted)
color: White to Light Yellow
CAS DataBase Reference: 700-49-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-22
Safety Statements: 26-36
WGK Germany: 3
RTECS: AU6264700
Hazard Note: Irritant
HazardClass: IRRITANT, IRRITANT-HARMFUL
HS Code: 29335990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 535087
Product name: 2-Fluoroadenine
Purity: 96%
Packaging: 1g
Price: $146
Updated: 2024/03/01

TCI Chemical

Product number: F0647
Product name: 2-Fluoroadenine
Purity: >98.0%(HPLC)(T)
Packaging: 200mg
Price: $18
Updated: 2024/03/01

TCI Chemical

Product number: F0647
Product name: 2-Fluoroadenine
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $72
Updated: 2024/03/01

Cayman Chemical

Product number: 30421
Product name: 2-Fluoroadenine
Packaging: 500mg
Price: $68
Updated: 2024/03/01

Cayman Chemical

Product number: 30421
Product name: 2-Fluoroadenine
Packaging: 1g
Price: $115
Updated: 2024/03/01

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2-Fluoroadenine Chemical Properties,Usage,Production

Description

2-Fluoroadenine is a purine nucleoside analog which has been investigated for suicide gene therapy for human malignancy. It has been used in the synthesis of heat shock protein 90 (Hsp90) inhibitors that have anticancer activity in vitro. It is also cytotoxic to CEM human leukemia cells with an IC50 value of 0.15 μM.

Chemical Properties

white to light yellow crystal powder

Uses

A purine nucleoside phosphorylase gene therapy for human malignancy.

Uses

2-Fluoroadenine is a fluorinated heterocyclic 2-ring compound. It is the base moiety for many carbocyclic and acyclic nucleoside analogues, which may be used in antineoplastic studies. 2-Fluoroadenine has been used as an intermediate for antineoplastic drugs such as fludarabine. fludarabine is a chemotherapy drug used in the treatment of chronic lymphocytic leukemia.

Definition

ChEBI: 2-fluoroadenine is an organofluorine compound that is adenine in which the hydrogen at position 2 (the carbon between the two nitrogens of the pyrimidine ring) is replaced by a fluorine. It has a role as an antineoplastic agent. It is an organofluorine compound and a member of purines.

2-Fluoroadenine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-Fluoroadenine Suppliers

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View Lastest Price from 2-Fluoroadenine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: 2-Fluoroadenine 700-49-2
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg/month
Release date: 2021-11-25

Henan Fengda Chemical Co., Ltd

Product: TCMDC-124283 700-49-2
Price: US $122.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-01-11

Henan Aochuang Chemical Co.,Ltd.

Product: 2-Fluoroadenine 700-49-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-22

700-49-2, 2-FluoroadenineRelated Search:

Fludarabine phosphate FLAVIN ADENINE DINUCLEOTIDE Adenine Sulfate Adenine Sulfamic acid Acetaminophen EC 2.6.1.2 3-Aminobenzotrifluoride Fludarabine 5'-Adenylic acid, 2-amino- beta-D-Arabinofuranose (9CI) Fludarabine Phosphate EP Impurity A Fludarabine Phosphate iMpurity B Fludarabine Phosphate iMpurity F Fludarabine Phosphate EP Impurity C Inosine, 2-fluoro- 2-Fluoroadenosine 2-Fluoro-2',3',5'-triacetoxyadenosine

2-fluoro-1h-purin-6-amin

2-fluoro-1h-purin-6-amine

2-fluoro-adenin

6-amino-2-fluoro-purin

nsc27364

2-Fluoro-9H-purin-6-amine

6-Amino-2-fluoro-1H-purine

BUTTPARK 25\01-01

2-FLUORO-6-AMINOPURINE

2-FLUOROADENINE

2-FLUORO-7(9)H-PURIN-6-YLAMINE

6-AMINO-2-FLUOROPURINE

2-fluoro-7H-purin-6-aMine

2-Fluoro-9H-purin-6-amine, 2-Fluoroadenine

6-Amino-2-fluoro-9H-purine

Fludarabine Phosphate EP Impurity D

2-fad

Fludarabine Phosphate Impurity 4

uoroadenine

Fludarabine Phosphate impurity 4/Fludarabine Phosphate EP Impurity D/2-fluoroadenine

Fludarabine EP impurity D (2-Fluoroadenine )

Fludarabine EP impurity D

Fludarabine Phosphate Impurity 4（Fludarabine Phosphate EP Impurity D）

2-Fluoroadenine&gt

9H-Purin-6-amine, 2-fluoro-

2-Fluoroadenine USP/EP/BP

2-Fluoroadenine(700-49-2)

Fludarabine Impurity 5

TCMDC-124283

2-Fluoro-7H-purin-6-amine (2-Fluoroadenine)

2-Fluoroadenine, 10 mM in DMSO

700-49-2

C5H4FN5

C5H4N5F

Purines

Heterocyclic Building Blocks

Building Blocks

Biochemistry

Nucleobases and their analogs

Nucleosides, Nucleotides & Related Reagents

Purine

Chemical Amines

Purines

Bases & Related Reagents

Heterocycles

Nucleotides

Fused Ring Systems

Miscellaneous

Amines

bc0001