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ChemicalBook > CAS DataBase List > 2-2-(2-Aminophenoxy)ethoxyaniline

2-2-(2-Aminophenoxy)ethoxyaniline

Uses
Product Name
2-2-(2-Aminophenoxy)ethoxyaniline
CAS No.
52411-34-4
Chemical Name
2-2-(2-Aminophenoxy)ethoxyaniline
Synonyms
BIS-(2-AMINOPHENOXY)-ETHANE;2'-(Ethylenedioxy)dianiline;2,2'-Diaminodiphenoxyalkane;1,2-Di(o-aminophenoxy)ethane;1,2-BIS(2-AMINOPHENOXY) ETHAN;2,2'-(ethylenedioxy)dianiline;1,2-BIS-(O-AMINOPHENOXY)ETHANE;2,2'-[1,2-Ethanediylbis(oxy)]dianiline;2,2'-[1,2-Ethanediylbis(oxy)]dianiline;2-[2-(2-Aminophenoxy)ethoxy]phenylamine
CBNumber
CB9855045
Molecular Formula
C14H16N2O2
Formula Weight
244.29
MOL File
52411-34-4.mol
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2-2-(2-Aminophenoxy)ethoxyaniline Property

Melting point:
131-132 °C
Boiling point:
452.9±30.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
vapor pressure 
0-0.17Pa at 25-129.5℃
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
DMSO (Slightly), Methanol (Slightly, Heated)
form 
powder to crystal
pka
4.56±0.10(Predicted)
color 
White to Light yellow to Light orange
InChI
InChI=1S/C14H16N2O2/c15-11-5-1-3-7-13(11)17-9-10-18-14-8-4-2-6-12(14)16/h1-8H,9-10,15-16H2
InChIKey
PSDFQEVOCCOOET-UHFFFAOYSA-N
SMILES
C(OC1=CC=CC=C1N)COC1=CC=CC=C1N
LogP
2.5 at 40℃ and pH6-7
Surface tension
72.1mN/m at 16mg/L and 20℃
CAS DataBase Reference
52411-34-4(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
HS Code 
29215900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

TCI Chemical
Product number
E1365
Product name
Ethylene Glycol Bis(2-aminophenyl) Ether
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$50
Updated
2025/07/31
TCI Chemical
Product number
E1365
Product name
Ethylene Glycol Bis(2-aminophenyl) Ether
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$151
Updated
2025/07/31
TRC
Product number
B405500
Product name
1,2-Bis(2-aminophenoxy)ethane
Packaging
25g
Price
$1295
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0019959
Product name
2,2'-(ETHYLENEDIOXY)DIANILINE
Purity
95.00%
Packaging
25G
Price
$2055.9
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
49845
Product name
1,2-Bis(2-aminophenoxy)ethane
Packaging
25g
Price
$2275
Updated
2021/12/16
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2-2-(2-Aminophenoxy)ethoxyaniline Chemical Properties,Usage,Production

Uses

2,2'-Diaminoethylene glycol diphenyl ether is a white crystalline powder with a melting point of 130-132℃. It is mainly used as a diazotizing component in the synthesis of the high-grade organic pigment Yellow CIPigment Yellow 180.

Chemical Properties

Off-White Crystalline Solid

Synthesis

51661-19-9

52411-34-4

The general procedure for the synthesis of 2,2'-diaminoethylene glycol diphenyl ether from 1,2-bis(2-nitrophenoxy)ethane was as follows: 60 g of 1,2-bis(2-nitrophenoxy)ethane, 51.7 g of sodium hydrosulfide solution with a mass fraction of 26% and 120 g of water were added to a 1 L autoclave. After replacing the air in the kettle with nitrogen, stirring was initiated and the reaction was heated to 130 °C, the reaction pressure was maintained at 0.2 MPa, and the reaction was held for 5 h. After completion of the reaction, the pressure was slowly released and cooled to 30~35 °C, followed by filtration to collect the crude product. The crude product was dissolved in 300 ml of water and acidified with hydrochloric acid. After drying, 44.4 g of the target product 2,2'-diaminoethylene glycol diphenyl ether was finally obtained in 91.0% yield and 99.65% purity.

References

[1] Zeitschrift fuer Naturforschung, B: Chemical Sciences, 1992, vol. 47, # 4, p. 547 - 552
[2] Chemistry of Heterocyclic Compounds (New York, NY, United States), 1988, vol. 24, p. 106 - 109
[3] Khimiya Geterotsiklicheskikh Soedinenii, 1988, vol. 24, # 1, p. 126 - 130
[4] Patent: CN105884631, 2016, A. Location in patent: Paragraph 0023; 0024
[5] Inorganic Chemistry, 2015, vol. 54, # 8, p. 3929 - 3936

2-2-(2-Aminophenoxy)ethoxyaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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2-2-(2-Aminophenoxy)ethoxyaniline Suppliers

Changzhou Yonghe Fine Chemical Co., Ltd.
Tel
0519-88552298 13921086978
Fax
86-519-88552298
Email
xuxiaosong1972@163.com
Country
China
ProdList
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
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China
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JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
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Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
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United States
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Chemsky(shanghai)International Co.,Ltd.
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021-50135380
Email
shchemsky@sina.com
Country
China
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32321
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50
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
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Maya High Purity Chemicals
Tel
+86 (573) 82222445 (0)18006601000 452520369
Fax
+86 (573) 82222643
Email
sales@maya-r.com
Country
China
ProdList
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Hangzhou Yuhao Chemical Technology Co., Ltd
Tel
0571-82693216
Fax
+86-571-82880190
Email
info@yuhaochemical.com
Country
China
ProdList
6387
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S.Z. PhyStandard Bio-Tech. Co., Ltd.
Tel
0755-83725681-603
Fax
+86 755 28094224
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China
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View Lastest Price from 2-2-(2-Aminophenoxy)ethoxyaniline manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
2,2'-[1,2-Ethanediylbis(oxy)]dianiline 52411-34-4
Price
US $3.00-9.00/KG
Min. Order
0.1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2025-06-27
Hebei Chuanghai Biotechnology Co,.LTD
Product
2, 2′- (Ethylenedioxy) Dianiline 52411-34-4
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-15
Shijiazhuang tongyang Import and Export Co., LTD
Product
1,2-Bis(2-aminophenoxy)ethane 52411-34-4
Price
US $15.00/Kg/Bag
Min. Order
1g
Purity
99
Supply Ability
50ton
Release date
2021-08-12

52411-34-4, 2-2-(2-Aminophenoxy)ethoxyanilineRelated Search:


  • 2,2'-diaminoethylene glycol diphenyl ether
  • BIS-(2-AMINOPHENOXY)-ETHANE
  • 1,2-BIS-(O-AMINOPHENOXY)ETHANE
  • Benzenamin, 2,2′-(1,2-ethanediylbis(oxy))bis-
  • 1,2-BIS(2-AMINOPHENOXY) ETHAN
  • 1,2,7,8-Dibenzo-1,8-diamino-3,6-dioxaoctane
  • 1,2-Di(o-aminophenoxy)ethane
  • 2,2'-[1,2-Ethanediylbis(oxy)]bis[benzenamine]
  • 2'-(Ethylenedioxy)dianiline
  • 2,2'-(ethane-1,2-diylbis(oxy))dianiline
  • 2-[2-(2-Aminophenoxy)ethoxy]phenylamine
  • 2,2'-(ethylenedioxy)dianiline
  • Ethylene glycol di(o-aminophenyl) ether
  • Ethylene Glycol Bis(2-aminophenyl) Ether
  • Benzenamine, 2,2'-[1,2-ethanediylbis(oxy)]bis-
  • 2-[2-(2-Aminophenoxy)ethoxy]phenylamine ISO 9001:2015 REACH
  • 2-[2-(2-Aminophenoxy)ethoxy]phenylamine 52411-34-4
  • 2,2'-[1,2-Ethanediylbis(oxy)]dianiline
  • 2,2'-Diaminodiphenoxyalkane
  • 2,2'-[1,2-Ethanediylbis(oxy)]dianiline
  • 52411-34-4
  • 52441-34-4
  • Aromatics
  • Chelating Agents & Ligands
  • Fluorescent Labels & Indicators