ChemicalBook > CAS DataBase List > proquazone
proquazone
- Product Name
- proquazone
- CAS No.
- 22760-18-5
- Chemical Name
- proquazone
- Synonyms
- 43-715;Arthrex;Biarsan;Biarison;SaH-43-715;proquazone;Proquazona;Proquazonum;Sandoz-43-715;7-methyl-4-phenyl-1-propan-2-ylquinazolin-2-one
- CBNumber
- CB9880256
- Molecular Formula
- C18H18N2O
- Formula Weight
- 278.35
- MOL File
- 22760-18-5.mol
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proquazone Property
- Melting point:
- 137-138°
- Boiling point:
- 436.12°C (rough estimate)
- Density
- 1.1707 (rough estimate)
- refractive index
- 1.5700 (estimate)
- pka
- 0.74±0.20(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- P839145
- Product name
- Proquazone
- Packaging
- 50mg
- Price
- $1100
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0012353
- Product name
- PROQUAZONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $499.39
- Updated
- 2021/12/16
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proquazone Chemical Properties,Usage,Production
Uses
Anti-inflammatory.
Uses
Proquazone is a non-steroidal anti-inflammatory drug.
Definition
ChEBI: Proquazone is a member of pyrimidines.
brand name
Arthrex (Novartis), Biarison (Swiss-Pharma, Egypt; Biochemie, Austria; ICN Alkaloida, Hungary; Sandoz, Finland, Turkey).
Clinical Use
Proquazone has been used successfully to treat rheumatoid polyarthritis. At 900 mg/d it is comparable in effect to 150 mg/d of indomethacin. Gastrointestinal disturbances are the principal adverse effects observed with its use.
Synthesis
Synthesis: proquazone is prepared by the
alkylation of 2-amino-4-methylbenzophenone
with 2-iodopropane in the presence of
sodium carbonate to give 4-methyl-2-[(1-
methylethyl)amino]benzophenone, which is
condensed with urethane in the presence of
zinc chloride at 190 ?C.
proquazone Preparation Products And Raw materials
Raw materials
Preparation Products
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proquazone Suppliers
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22760-18-5, proquazone Related Search:
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