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Quinagolide hydrochloride

Product Name
Quinagolide hydrochloride
CAS No.
94424-50-7
Chemical Name
Quinagolide hydrochloride
Synonyms
SDZ 205-502;Norprolac Hydrochloride;CV205-502 hydrochloride;QUINAGOLIDE HYDROCHLORIDE;Quinagolide hydrochloride (CV205-502 hydrochloride);(3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride;rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride;(3α,4aα,10aβ)-N,N-Diethyl-N'- (1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride;(+/-)-N,N-diethyl-N'-quinolinyl>sulfamide hydrochloride
CBNumber
CB9995839
Molecular Formula
C20H34ClN3O3S
Formula Weight
432.02
MOL File
94424-50-7.mol
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Quinagolide hydrochloride Property

Melting point:
234-236°
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 43 mg/mL (99.53 mM)
form 
Solid
color 
White to off-white
CAS DataBase Reference
94424-50-7(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
Q580500
Product name
QuinagolideHydrochloride
Packaging
25mg
Price
$13390
Updated
2021/12/16
TRC
Product number
Q580500
Product name
QuinagolideHydrochloride
Packaging
50mg
Price
$15490
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004012
Product name
QUINAGOLIDE HYDROCHLORIDE
Purity
95.00%
Packaging
25MG
Price
$15303.75
Updated
2021/12/16
ChemScene
Product number
CS-5136
Product name
Quinagolidehydrochloride
Packaging
5mg
Price
$420
Updated
2021/12/16
ChemScene
Product number
CS-5136
Product name
Quinagolidehydrochloride
Packaging
10mg
Price
$600
Updated
2021/12/16
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Quinagolide hydrochloride Chemical Properties,Usage,Production

Description

Quinagolide is a potent and specific non-ergot dopamine D2 agonist launched in the Netherlands for the treatment of hyperprolactinemia. Quinagolide is effective in inhibiting prolactin secretion by human pituitary tumor and hyperprolactinemia in vitro and in viva A daily dose of as low as 60 pg is able to achieve a pronounced and prolonged suppressive effect on serum prolactin and growth hormone secretion. It is also effective in providing relief from associated effects such as infertility, galactorrhea, oligomenorrhea, amenorrhea, loss of IibMo and impotence. Compared with the most widely used antiprolactin, bromocriptine, quinagolide is more potent in vivo with a longer duration of action and fewer side effects. A recent study showed that acute administration of quinagolide suppresses growth hormone secretion in acromegalic patients and thus could serve as an alternative therapy in acromegaly.

Originator

Sandoz (Switzerland)

Uses

Quinagolide is a nonergot dopamine D2-receptor agonist. Quinagolide acts as an prolactin inhibitor.

brand name

Norprolac

Quinagolide hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Quinagolide hydrochloride Suppliers

J & K SCIENTIFIC LTD.
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94424-50-7, Quinagolide hydrochlorideRelated Search:


  • QUINAGOLIDE HYDROCHLORIDE
  • (3S,4aS,10aR)-3-(Diethylsulfamoylamino)-6-hydroxy-1-propyl-3,4,4a,5,10,10a-hexahydro-2H-benzo[g]quinoline hydrochloride
  • Quinagolide hydrochloride (CV205-502 hydrochloride)
  • (+/-)-N,N-diethyl-N'-<(3α,4aα,10aβ)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propyl-3-benzo<g>quinolinyl>sulfamide hydrochloride
  • (3α,4aα,10aβ)-N,N-Diethyl-N'- (1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl)sulfaMide Monohydrochloride
  • Norprolac Hydrochloride
  • rel-N,N-Diethyl-N'-[(3R,4aR,10aS)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo[g]quinolin-3-yl]sulfaMide Hydrochloride
  • SDZ 205-502
  • CV205-502 hydrochloride
  • 94424-50-7
  • C20H34ClN3O3S
  • Amines
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
  • Sulfur & Selenium Compounds