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Standard

Standard Substance Protein assay reagent Titration standard Forensic and veterinary standards Analytical Standards Spectral Standards Chemistry Cosmetics Standard Volatile organic compounds (VOCs) Clinical Standards Veterinary drug and Pesticide residues Agricultural and environmental standards Chromatography Standards Life Science Standards Food and cosmetics standards Food and beverage standards Inorganic single element standard solution Pharmaceutical Impurity Reference Standards Water Testing Standards Organic Standard Solutions Organic Pollutant Standards Chinese medicine standards
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In the analysis work, it often demanded to apply high-quality compound with the exact content being accurate in order to be compared as the detection control or used to calibrate the instrument, the compound is known as standard sample.
Standard refers to the standard substance used for measuring the potency of biological products. When the production department submits to a higher authority for approval of the quality standard of the biological product, they should also provide the standard sample (indicated in unit (μ)) used for measuring the potency of the tested product.

According to different application, the verification products can be divided into biological standard for the testing of biological products, endocrine drugs, antibiotics and other bioassay and chemical standards including:
1 chemical standards used for calibration of the instrument;
2 chemical reference standards used for calibration of the ultraviolet or infrared spectrum of the drugs;
3 control standards used for the purity test of drugs as well as the impurity control or as the control standards for content determination of the medicine.

In the page 67 of the appendix in the People's Republic of China Pharmacopoeia 1990 1st edition, we can find hundreds kinds of standards including bornyl ester acetate, eugenol and panaxadiol as well as 39 kinds of control medicine for the purify inspection of traditional Chinese medicine, impurity control or the content determination.

International standards
This refers to standard sample, with the potency units of the existing international standard sample potency units as baseline, undergoing further calibration of its potency units on the basis of a wide range of international cooperation. Its potency is expressed in 1U. For a certain product, for the establishment of the first international standard sample, the determination of its potency units should be consulted and decided by the Committee of Experts before the announcement. The international standard is a standard reference substance for worldwide preparation of national standards, so that the international standards can achieve unity.

Reagents and standards
All reagents in the food analysis laboratories should be clearly labeled to indicate the following: 1 name; 2 the date of preparation; 3 Signature from the people in charge; 4 if necessary, we need to add content such as safety and validity and so on.
Most food analysis should use standard sample as reference for qualitative and quantitative determination. The standard sample should be classified according to the following classification methods: 1 international standard; 2 national standards; 3 internal standard; 4 other standards.
Receptacle for reference standards should be clearly affixed to the label, to indicate the following: 1 name; 2 standard document number; 3 Opening times; 4 Validity; 5 Signature.
In addition, the laboratory should keep all the necessary specific files for all the necessary reference standards.
Capacity analysis standard solution should also be strictly managed. It should be clearly posted on all the standard solution containers with labels to indicate: 1 name; 2 concentration; 3 formulation date; 4 No of formulated procedures; 5 storage conditions; 6 validity; 7 Signature from people in charge.

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Structure:
Chemical Name:
4-(4-Hydroxy-3-hydroxymethyl-phenoxy)-benzonitrile
MF:
C14H11NO3
Chemical Name:
Cabozantinib impurity P
Chemical Name:
Rotigotine Impurity 7
Chemical Name:
Nicorandil Impurity B
Chemical Name:
Cilastatin Impurity 8
Structure:
Chemical Name:
Tamsulosin impurity E
MF:
C20H28N2O5S
Chemical Name:
Flucloxacillin Impurity H
Chemical Name:
Cefminox Impurity 2
Chemical Name:
Afatinib Impurity 56
Chemical Name:
Aprepitant Impurity 34
Chemical Name:
Bosutinib Impurity 14
Chemical Name:
Brivaracetam Impurity 16
Structure:
Chemical Name:
Etoricoxib Impurity 41
CAS:
855307-80-1
MF:
C18H13ClN2O2S
Chemical Name:
Fluvoxamine Impurity 10
Structure:
Chemical Name:
Nintedanib Impurity 50
CAS:
2410284-90-9
MF:
C56H52N8O8
Chemical Name:
Olopatadine Impurity 8
Chemical Name:
Oseltamivir Impurity 36
Structure:
Chemical Name:
Palbociclib Impurity 61
CAS:
2222404-53-5
MF:
C14H20N4O4
Structure:
Chemical Name:
Bezafibrate Impurity D
CAS:
41859-58-9
MF:
C21H24ClNO4
Structure:
Chemical Name:
Cloxacillin Sodium EP Impurity B (Mixture of Diastereomers)
CAS:
1642559-64-5
MF:
C18H20ClN3O4S
Structure:
Chemical Name:
Ezetimibe Related Impurity 37
CAS:
204589-68-4
MF:
C24H19F2NO2
Chemical Name:
Palbociclib Impurity 41
Chemical Name:
Saxagliptin Impurity 8
Chemical Name:
Tenofovir Impurity 63
Chemical Name:
Ticagrelor Impurity 99
Chemical Name:
Ticagrelor Impurity 114
Chemical Name:
Ticagrelor Impurity 98
Chemical Name:
Tofacitinib Impurity 118
Chemical Name:
Trelagliptin Impurity 23
Chemical Name:
Vildagliptin Impurity 33
Chemical Name:
Vildagliptin Impurity 44
Structure:
Chemical Name:
Voriconazole Impurity 16
CAS:
1157981-64-0
MF:
C10H7F2N3O
Chemical Name:
Itraconazole iMpurity 3
Structure:
Chemical Name:
1-(3,5-bis(benzyloxy)phenyl)-2,2-dibromoethan-1-one
MF:
C22H18Br2O3
Chemical Name:
Axitinib Impurity 8
Chemical Name:
Agomelatine Impurity 11
Chemical Name:
Saxagliptin Impurity 7
Chemical Name:
Cinacalcet Impurity 23
Chemical Name:
Erlotinib Impurity 24
Chemical Name:
Ticagrelor Impurity 47
Chemical Name:
Edaravone Impurity 10
Chemical Name:
Empagliflozin Impurity 10
Chemical Name:
Canagliflozin Impurity 10
Chemical Name:
Rivaroxaban Impurity 35
Chemical Name:
Febuxostat Impurity 67
Structure:
Chemical Name:
Hydroxytyrosol 4-O-glucoside
CAS:
54695-80-6
MF:
C14H20O8
Chemical Name:
Riociguat IMpurtiy A
Chemical Name:
Peramivir Impurity C
Chemical Name:
Lincomycin sulfoxide Impurity 6
Chemical Name:
Metronidazole IMpurity 5
Chemical Name:
Sulpiride Impurity 5
Structure:
Chemical Name:
methyl 3-(4-(3-(ethylamino)-2-hydroxypropoxy)phenyl)propanoate hydrochloride
MF:
C15H24ClNO4
Chemical Name:
Tacrolimus Impurity F
Chemical Name:
Cefminox Impurity E
Structure:
Chemical Name:
Palonosetron
CAS:
135729-56-5
MF:
C19H22N2O
Structure:
Chemical Name:
4-[4-(diMethylaMino)-1-(4-fluorophenyl)-1-buten-1-yl]-3-(hydroxyMethyl)-benzonitrile (CitalopraM Olefinic IMpurity)
CAS:
920282-75-3
MF:
C20H21FN2O
Structure:
Chemical Name:
7-Methoxy-4-oxo-1,4-dihydroquinoline-6-carboxylic acid
CAS:
417721-34-7
MF:
C11H9NO4
Chemical Name:
Pemetrexed
Structure:
Chemical Name:
Venlafaxine
MF:
C17H27NO2
Structure:
Chemical Name:
(S)-4,5-dichloro-N-((2-oxo-3-(4-(3-oxoMorpholino)phenyl)oxazolidin-5-yl)Methyl)thiophene-2-carboxaMide
CAS:
1770812-37-7
MF:
C19H17Cl2N3O5S
Structure:
Chemical Name:
2-Propen-1-one, 1-[4-[4-aMino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyriMidin-1-yl]-1-piperidinyl]-
CAS:
936563-92-7
MF:
C25H24N6O2
Structure:
Chemical Name:
8-cyclopentyl-5-Methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)aMino)-6-vinylpyrido[2,3-d]pyriMidin-7(8H)-one
MF:
C24H29N7O
Structure:
Chemical Name:
D-Alanine, N-[[P(R),2'R]-2'-deoxy-2'-fluoro-2'-Methyl-P-phenyl-5'-uridylyl]-, 1-Methylethyl ester
CAS:
1496552-16-9
MF:
C22H29FN3O9P
Structure:
Chemical Name:
D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester
CAS:
15136-32-0
MF:
C21H32N2O5
Structure:
Chemical Name:
4-Nitro-2-phenoxyphenol
CAS:
70995-08-3
MF:
C12H9NO4
Structure:
Chemical Name:
Sofosbuvir Impurity
CAS:
1233335-82-4
MF:
C16H25FN3O9P
Structure:
Chemical Name:
Ethyl 3,4-O-isopropylideneshikiMate
CAS:
136994-78-0
MF:
C12H18O5
Structure:
Chemical Name:
4-Vinyl-piperidine-4-carboxylic acid ethyl ester
CAS:
1509910-91-1
MF:
C10H17NO2
Structure:
Chemical Name:
(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoic acid
CAS:
1039307-95-3
MF:
C18H21NO2
Chemical Name:
EMpagliflozin iMpurity 16
Structure:
Chemical Name:
((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester
CAS:
149709-58-0
MF:
C20H23NO3
Structure:
Chemical Name:
1-(2,3-DiMethylphenyl)-1-(1H-iMidazol-4-yl)ethanol
CAS:
86347-12-8
MF:
C13H16N2O
Structure:
Chemical Name:
(R)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
CAS:
1612153-32-8
MF:
C20H20FNO4
Structure:
Chemical Name:
(S)-3-((R)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one
CAS:
528565-93-7
MF:
C20H20FNO4
Chemical Name:
Posaconazole iMpurity 3
Structure:
Chemical Name:
S, R-Isovalganciclovir Impurity
CAS:
1356932-18-7
MF:
C14H22N6O5
Structure:
Chemical Name:
Sofosbuvir Impurity 8
CAS:
944476-44-2
MF:
C24H22N2O8
Structure:
Chemical Name:
135270-13-2
CAS:
135270-13-2
MF:
C12H11F2N3O
Structure:
Chemical Name:
1-((2'-cyanobiphenyl-4-yl)methyl)-4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylic acid
CAS:
1098100-87-8
MF:
C26H23N3O2
Chemical Name:
Fimasartan Impurity
Structure:
Chemical Name:
2-(((5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)(methyl)amino)succinic acid
MF:
C21H20FN3O6S
Structure:
Chemical Name:
()-Olivil 4″-O-glucoside
CAS:
76880-93-8
MF:
C26H34O12
Structure:
Chemical Name:
2-(DIETHYLAMINO)-N-(2,4-DIMETHYLPHENYL)ACETAMIDE
CAS:
17289-53-1
MF:
C14H22N2O
Structure:
Chemical Name:
Isatin indicator solution
MF:
C8H5NO2
Chemical Name:
Oxaliplatin impurity
Structure:
Chemical Name:
NiMesulide EP IMpurity
CAS:
38880-53-4
MF:
C7H8N2O5S
Structure:
Chemical Name:
Alogliptin Impurity D
CAS:
1926163-25-8
MF:
C61H86N16O13
Chemical Name:
Moxifloxacin Impurities
Structure:
Chemical Name:
Parecoxib Impurity K
CAS:
198471-69-1
MF:
C17H16N2O3S
Structure:
Chemical Name:
Linagliptin Impurity K
CAS:
1638744-06-5
MF:
C25H29BrN8O2
Structure:
Chemical Name:
(R)-2-((6-(3-((3-(2-cyano-5-fluorobenzyl)-1-methyl-2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)amino)piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile
CAS:
1917324-13-0
MF:
C31H28F2N8O4
Structure:
Chemical Name:
L-Phenylalanine, N-[(5,7-dichloro-1,2,3,4-tetrahydro-6-isoquinolinyl)carbonyl]-3-(methylsulfonyl)-, phenylmethyl ester, hydrochloride (1:1)
CAS:
1194550-65-6
MF:
C27H27Cl3N2O5S
Structure:
Chemical Name:
Alogliptin Related Compound 23
CAS:
1618644-29-3
MF:
C20H13ClN4O2
Chemical Name:
Etoricoxib Impurity 14
Chemical Name:
Riociguat Impurtiy 3
Chemical Name:
Trelagliptin Impurity 2
Structure:
Chemical Name:
Chlorhexidine Impurity B
CAS:
1308292-89-8
MF:
C16H26ClN9O
Chemical Name:
Dapoxetine Impurity D
Chemical Name:
Eltrombopag Impurity 5
Structure:
Chemical Name:
Exemestane Impurity 1
CAS:
159354-61-7
MF:
C20H24O3