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4-(3-fluoro-benzyloxy)-benzaldehyde

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4-(3-fluoro-benzyloxy)-benzaldehyde Basic information

Product Name:
4-(3-fluoro-benzyloxy)-benzaldehyde
Synonyms:
  • Benzaldehyde, 4-[(3 -fluorophenyl)Methoxy]-
  • 4-[(3-fluorophenyl)methoxy]-Benzaldehyde
  • Safinamide mesylate Intermediate
  • Safinamide mesylate Intermediate 1
  • 4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE Intermediate 1
  • 4-(3-Fluorobenzyloxy)benzaldehyde >
  • Safinamide Intermediate 1
  • 4-(3-FLUORO-BENZYLOXY)-BENZALDEHYDE ISO 9001:2015 REACH
CAS:
66742-57-2
MF:
C14H11FO2
MW:
230.23
EINECS:
613-982-6
Product Categories:
  • Intermediate
Mol File:
66742-57-2.mol
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4-(3-fluoro-benzyloxy)-benzaldehyde Chemical Properties

Melting point:
46.0 to 50.0 °C
Boiling point:
265°C/3mmHg(lit.)
Density 
1.211±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
solubility 
soluble in Methanol
form 
Solid:crystalline
color 
White to Almost white
CAS DataBase Reference
66742-57-2
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Safety Information

HS Code 
2913.00.4000
HazardClass 
IRRITANT
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4-(3-fluoro-benzyloxy)-benzaldehyde Usage And Synthesis

Uses

4-(3-Fluorobenzyloxy)benzaldehyde is useful for organic reactions and synthesis.

Synthesis

4-(3-fluoro-benzyloxy)-benzaldehyde is synthesized by the reaction of 4-Hydroxybenzaldehyde with 3-fluorobenzyl bromide. 4-Hydroxybenzaldehyde, 3-fluorobenzyl bromide, potassium carbonate, and acetone were sequentially added to a single-neck round bottom flask. Reaction at 60 ° C for 5 h. Cool to room temperature, filter, and collect the filtrate.Purification by direct column chromatography. 4-(3-fluoro-benzyloxy)-benzaldehyde was obtained as a white solid (1.78 g, 94.4%).

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