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N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine

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N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine Basic information

Product Name:
N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine
Synonyms:
  • BIS(TRIMETHYLSILYL)CYTOSINE
  • 4-Pyrimidinamine, N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-
  • n-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamin
  • N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]-4-pyrimidinamine
  • Bis-(Trimethylsilyl) Cytosine (BSC)
  • O2,N4-Bis(trimethylsilyl)cytosine
  • Pyrimidine, 2-(trimethylsiloxy)-4-[(trimethylsilyl)amino]-
  • N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine
CAS:
18037-10-0
MF:
C10H21N3OSi2
MW:
255.46
EINECS:
241-945-0
Mol File:
18037-10-0.mol
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N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine Chemical Properties

Melting point:
122°C
Boiling point:
123 °C
Density 
0.994±0.06 g/cm3(Predicted)
Flash point:
65°C
pka
4.96±0.10(Predicted)
Hydrolytic Sensitivity
7: reacts slowly with moisture/water
CAS DataBase Reference
18037-10-0(CAS DataBase Reference)
NIST Chemistry Reference
4-Pyrimidinamine, n-(trimethylsilyl)-2-[(trimethylsilyl)oxy]-(18037-10-0)
EPA Substance Registry System
4-Pyrimidinamine, N-(trimethylsilyl)-2-[(trimethylsilyl)oxy]- (18037-10-0)
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Safety Information

TSCA 
Yes
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N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine Usage And Synthesis

Uses

2,4-Bis(trimethylsilyl)cytosine is an intermediate used in the synthesis of 1’-Epi Gemcitabine Hydrochloride (E588510), which is an α-Anomer of Gemcitabine.

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