ENPROFYLLINE Chemical Properties

Melting point:

287-289 °C

Density 

1.38 g/cm3

storage temp. 

2-8°C

solubility 

DMSO: soluble

form 

solid

pka

10.26±0.20(Predicted)

color 

white

CAS DataBase Reference

41078-02-8

Safety Information

Hazard Codes 

Xn

Risk Statements 

20/21/22

Safety Statements 

36

WGK Germany 

3

RTECS 

UO8439700

MSDS

• Language:English Provider:SigmaAldrich

ENPROFYLLINE Usage And Synthesis

Description

3-Propylxanthine is a xanthine derivative that antagonizes adenosine receptors (K_is = 44, 32, and 6.3 μM for A₁, A_2A, and A_2B, respectively) and cAMP phosphodiesterase (K_i = 42 μM). Through these actions, 3-propylxanthine induces smooth muscle relaxation, blocks smooth muscle contraction and VEGF secretion driven by adenosine receptor agonists, and reduces bronchial hyperresponsiveness.

Uses

Bronchodilator.

Uses

Enprofylline is a xanthine lacking adenosine receptor antagonism.

Definition

ChEBI: Xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic n uropathy.

ENPROFYLLINE(41078-02-8)Related Product Information

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