Cefminox
Cefminox Basic information
- Product Name:
- Cefminox
- Synonyms:
-
- (6r-(6-alpha,7-alpha))-7-((((2-amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
- (6r,7s)-7-(2-(((s)-2-amino-2-carboxyethyl)thio)acetamido)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- CEFMINOX SOUDIUM
- 7-[[2-[(2-amino-2-carboxyethyl)thio]-1-oxoethyl]amino]-7-methoxy-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[(2-amino-2-carboxyethyl)thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, [6R-[6α,7α,7(S*)]]-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(2S)-2-amino-2-carboxyethyl]thio]acetyl]amino]-7-methoxy-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt, (6R,7S)-
- Cefminox sodium salt
- Meicelin
- CAS:
- 75481-73-1
- MF:
- C16H21N7O7S3
- MW:
- 519.58
- Mol File:
- 75481-73-1.mol
Cefminox Chemical Properties
- CAS DataBase Reference
- 75481-73-1(CAS DataBase Reference)
Cefminox Usage And Synthesis
Definition
ChEBI: Cefminox is a second-generation cephamycin antibiotic having [(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl and 2-{[(2S)-2-amino-2-carboxyethyl]sulfanyl}acetamido side-groups located respectively at positions 3 and 7beta of the cephem nucleus. A broad-spectrum bactericide, it is especially effective against Gram-negative and anaerobic bacteria. It is a cephamycin and a member of tetrazoles. It is a conjugate acid of a cefminox(1-).
Antimicrobial activity
A semisynthetic cephamycin. Activity is similar to that of
cefoxitin and cefotetan, but the activity against enterobacteria
and B. fragilis is somewhat better . C. difficile
is inhibited by 4–16 mg/L. It is stable to the common
β-lactamases of enterobacteria and Bacteroides spp.
A 15-min intravenous infusion of 1 g achieves a serum concentration
of 30 mg/L after 1 h. The plasma half-life is c. 2 h
and around 68% is protein bound.
Its safety profile and uses are similar to those of other
cephamycins. It is available in Japan.
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Cefminox(75481-73-1)Related Product Information
- Glycine
- 2-Methoxyethanol
- ALTRENOGEST
- Acetaminophen
- Ceftriaxone sodium
- Oxygen
- 7-TMCA
- (6R-(6-alpha,7-alpha))-7-((((2-Amino-2-carboxyethyl)thio)acetyl)amino)-7-methoxy-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid monosodium salt
- 1-METHYL-3-AZETIDINOL
- 3-METHOXY-AZETIDINE
- ACETAMINOPHENOL BP/USP
- AMINO ACIDS
- Cefminox
- 1H-Tetrazole, 5-((3-(ethylthio)propyl)thio)-1-methyl-
- Methoxy
- CEFMINOXSODIUM