Acetiromate Chemical Properties

Melting point:

238°C

Density 

2.3074 (estimate)

Acetiromate Usage And Synthesis

Originator

Acetiromate ,ZYF Pharm Chemical

Uses

Acetiromate is a thyroxine analogue. Acetiromate is an antilipidemic drug for hyperlipidemia[1].

Manufacturing Process

To 3 parts of 3,5-diiodo-4-(3-iodo-4-hydroxyphenoxy)benzoic acid 10 parts of acetic acid anhydride was added and mixture was heated on oil bath for some hours. In the result of this reaction amorphous precipitate was obtained. After recrystallization from glacial acetic acid 2.4 parts of 3,5-diiodo-4-(3-iodo-4- acetoxyphenoxy)benzoic acid were obtained.

Therapeutic Function

Antihyperlipidemic

References

[1] S Kumaoka. Long-term administration of 3,5-diodo-4(3'-iodo4'-acetoxyphenoxy) benzoic acid (acetiromate) in hyperlipidemic patients. Endocrinol Jpn. 1974 Aug;21(4):355-60. DOI:10.1507/endocrj1954.21.355

Acetiromate(2260-08-4)Related Product Information

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