3,5-DIIODO-4-HYDROXYBENZALDEHYDE Chemical Properties

Melting point:

202-203°C

Boiling point:

284.1±40.0 °C(Predicted)

Density 

2.602±0.06 g/cm3(Predicted)

storage temp. 

-20°C Freezer, Under Inert Atmosphere

solubility 

Chloroform (Slightly, Sonicated), DMSO (Slightly)

form 

Solid

pka

4.89±0.23(Predicted)

color 

White to Pale Yellow

Water Solubility 

Insoluble in water. Sparingly soluble in chloroform and methanol.

Sensitive 

Air & Light Sensitive

BRN 

1283414

InChI

InChI=1S/C7H4I2O2/c8-5-1-4(3-10)2-6(9)7(5)11/h1-3,11H

InChIKey

WHLUEIMENHLCMY-UHFFFAOYSA-N

SMILES

C(=O)C1=CC(I)=C(O)C(I)=C1

CAS DataBase Reference

1948-40-9(CAS DataBase Reference)

Safety Information

Risk Statements 

36/37/38

Safety Statements 

26-36

HS Code 

2913000090

MSDS

• Language:English Provider:ALFA

3,5-DIIODO-4-HYDROXYBENZALDEHYDE Usage And Synthesis

Chemical Properties

Pale Beige Solid

Uses

3,5-Diiodo-4-hydroxybenzaldehyde (cas# 1948-40-9) is a compound useful in organic synthesis.

Synthesis

3,5-Diiodo-4-hydroxybenzaldehyde was prepared as follows: in a 100 mL round bottom flask, 4-hydroxybenzaldehyde (1.0 g, 8.19 mmol), sodium periodate (1.75 g, 8.19 mmol), and NaCl (957 mg, 16.38 mmol) were dissolved in acetic acid (30 mL). H2O (3 mL) was added at room temperature. The reaction mixture was stirred at room temperature for 10 min, then potassium iodide (2.72 g, 16.4 mmol) was added and the reaction mixture was stirred at room temperature for 96 hours. The reaction mixture was diluted with EtOAc (25 mL) and 1 M aqueous sodium thiosulfate. The solution (25 mL) was added and the resulting mixture was stirred for 15 minutes. The solution was poured into 250 mLErlenmeyer and washed with EtOAc (50 mL) and 1 M aqueous sodium thiosulfate. solution (50mL) and the resulting solution was stirred for another 15 minutes. The organic layer was separated and the aqueous phase was further extracted with EtOAc (3 x 50 mL). The combined organic layers were washed with brine (100 mL), dried over Na2SO4, filtered and concentrated to dryness to afford 4-hydroxy-3,5-diiodobenzaldehyde (2.91 g, 95% yield) as a light yellow solid.

3,5-DIIODO-4-HYDROXYBENZALDEHYDE(1948-40-9)Related Product Information

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