Prunetin Chemical Properties

Melting point:

240-242°C

Boiling point:

346.76°C (rough estimate)

Density 

1.2160 (rough estimate)

refractive index 

1.6200 (estimate)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.

form 

Powder

pka

6.35±0.20(Predicted)

BRN 

292155

LogP

3.530 (est)

CAS DataBase Reference

552-59-0(CAS DataBase Reference)

Safety Information

Safety Statements 

22-24/25

WGK Germany 

3

RTECS 

DJ3100050

F 

10

MSDS

• Language:English Provider:5,4'-Dihydroxy-7-methoxyisoflavone
• Language:English Provider:SigmaAldrich

Prunetin Usage And Synthesis

Uses

Prunetin is isoflavone with diverse biological activities. Prunetin is an antagonist of the progesterone receptor when used at concentrations of 25 and 50 μM.

Definition

ChEBI: A hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group.

Enzyme inhibitor

This Prunus species isoflavone (FW = 284.27 g/mol; CAS 552-59-0; melting point = 240°C), also known as 4’,5-dihydroxy-7- methoxyisoflavone and 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-1- benzopyran-4-one, inhibits alcohol dehydrogenase, aldehyde dehydrogenase, 3’,5’-cyclic-nucleotide phosphodiesterase, phosphodiesterase 4, and protein-tyrosine kinase. Its 4’-glucoside is prunitrin. Methylated isoflavones, such as prunetin, are rapidly converted by CYP1A2 to more active genistein and daidzein, which inhibit.formation of acetaminophen from phenacetin with an IC50 value of 16 μM.

Prunetin(552-59-0)Related Product Information

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