2-Aminoimidazole
2-Aminoimidazole Basic information
- Product Name:
- 2-Aminoimidazole
- Synonyms:
-
- 1H-IMIDAZOL-2-AMINE
- 2-AMINOIMIDAZOLE
- 2-Amino-1H-Imidazole
- 2-Aminoimidazole(2-Aminoimidazole hemisulfate)
- 2-aminoIMIDAZOLE:1h-imidazol-2-amine
- CAS:
- 7720-39-0
- MF:
- C3H5N3
- MW:
- 83.09
- EINECS:
- 231-751-4
- Product Categories:
-
- Imidaxoles
- Mol File:
- 7720-39-0.mol
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2-Aminoimidazole Chemical Properties
- Boiling point:
- 313.1±25.0 °C(Predicted)
- Density
- 1.313±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- 15.06±0.10(Predicted)
- form
- solid
- color
- Brown
- CAS DataBase Reference
- 7720-39-0(CAS DataBase Reference)
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2-Aminoimidazole Usage And Synthesis
Uses
2-Aminoimidazole is a potent antibiofilm agent that can be used as an adjuvant to antimicrobial. 2-aminoimidazoles disrupts the ability of bacteria to protect themselves by inhibiting biofilm formation and genetically-encoded antibiotic resistance traits. 2-Aminoimidazole is also a weak noncompetitive inhibitor of human arginase I with a Ki of 3.6 mM.
in vivo
The 2-aminoimidazole analogs A1P (80 μg/g, Nebulization, Once in total) can reduce airways hyperresponsiveness to methacholine in an acute (3-week) ovalbumin (OVA)-sensitization and -challenge murine model[3].
| Animal Model: | Female Balb/C mice (6 - 8 weeks old) [Acute (3-week) ovalbumin (OVA)-sensitization and -challenge murine model][3] |
| Dosage: | 80 μg/g, Once in total |
| Administration: | Nebulization |
| Result: | The 2-aminoimidazole analogs A1P attenuated significantly the total resistance of the respiratory system (R) and the maximum resistance of the central airways (RN) following methacholine challenge. |
2-Aminoimidazole Preparation Products And Raw materials
Raw materials
2-AminoimidazoleSupplier
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2-Aminoimidazole(7720-39-0)Related Product Information
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- 2-AMINOIMIDAZOLE HEMISULFATE,2-AMINOIMIDAZOLE SULFATE (2:1),2-AMINOIMIDAZOLE SULFATE,2-AMINOIMIDAZOLE SULPHATE
- 4,5-DICYANO-2-AMINOIMIDAZOLE
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- COCO AMINE
- ACETAMINOPHENOL BP/USP
- 2-Aminoimidazole
- 2-AMINOIMIDAZOLE HYDROCHLORIDE