Ethyl potassium malonate Chemical Properties

Melting point:

194 °C (dec.) (lit.)

storage temp. 

Inert atmosphere,Room Temperature

solubility 

Methanol (Slightly), Water (Slightly)

form 

Powder or Cyrstals

color 

White

PH

pH(50g/l, 25℃) : 5.5～8.0

Water Solubility 

soluble

Sensitive 

Hygroscopic

BRN 

3721682

InChIKey

WVUCPRGADMCTBN-UHFFFAOYSA-M

CAS DataBase Reference

6148-64-7(CAS DataBase Reference)

Safety Information

Hazard Codes 

Xi

Risk Statements 

36/37/38

Safety Statements 

26-36-37/39

WGK Germany 

2

HS Code 

29171910

MSDS

• Language:English Provider:Ethyl potassium malonate
• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

Ethyl potassium malonate Usage And Synthesis

Chemical Properties

white crystals or powder

Uses

Ethyl potassium malonate is used as a competitive inhibitor of the enzyme succinate dehydrogenase. It acts as a precursor to produce (trimethylsilyl)ethyl malonate, which is utilized to prepare beta-ketoesters by acylation. Further, it reacts with aryl nitriles to prepare beta-amino acrylates in the presence of zinc chloride and a catalytic amount of Hünig's base. In addition to this, it serves as an intermediate for the preparation of ethyl tert-butyl malonate.

Uses

Ethyl potassium malonate (potassium ethyl malonate) may be used to generate (trimethylsilyl)ethyl malonate in situ, which can be acylated to prepare a variety of β-ketoesters or alkylidene malonates.

General Description

Ethyl potassium malonate (potassium ethyl malonate) reacts with aryl nitriles in the presence of zinc chloride and a catalytic amount of Hünig′s base to yield β-amino acrylates. Ethyl potassium malonate is formed as an intermediate during the synthesis of ethyl tert-butyl malonate.

Ethyl potassium malonate(6148-64-7)Related Product Information

• Ethyl malonyl chloride
• Diethyl malonate
• Malonic acid
• Diethyl methylmalonate
• Potassium chloride
• Potassium Acetate
• Potassium Citrate
• 3-tert-Butoxy-3-oxopropanoic acid
• Potassium 3-methoxy-3-oxopropanoate
• Ethyl hydrogen malonate
• Dimethyl malonate
• MONO-ETHYL SUCCINATE
• Ethyl Succinyl Chloride
• Diethyl ethylmalonate
• Potassium iodide
• Potassium persulfate
• Diisopropyl malonate
• TERT-BUTYL ETHYL MALONATE