METHYL OXALYL CHLORIDE Chemical Properties

Boiling point:

118-120 °C (lit.)

Density 

1.332 g/mL at 25 °C (lit.)

refractive index 

n20/D 1.419(lit.)

Flash point:

116 °F

storage temp. 

Inert atmosphere,2-8°C

solubility 

Chloroform (Slightly), Ethyl Acetate

form 

Liquid

color 

Clear

Water Solubility 

Miscible with water.

Sensitive 

Moisture Sensitive

BRN 

1071541

Stability:

Hygroscopic

InChIKey

ZXUQEPZWVQIOJE-UHFFFAOYSA-N

CAS DataBase Reference

5781-53-3(CAS DataBase Reference)

EPA Substance Registry System

Acetic acid, chlorooxo-, methyl ester (5781-53-3)

Safety Information

Hazard Codes 

C,F

Risk Statements 

34-37-10-36-14

Safety Statements 

26-36/37/39-45-16

RIDADR 

UN 2920 8/PG 2

WGK Germany 

3

F 

9-21

TSCA 

Yes

HazardClass 

8

PackingGroup 

II

HS Code 

29171900

MSDS

• Language:English Provider:SigmaAldrich
• Language:English Provider:ACROS
• Language:English Provider:ALFA

METHYL OXALYL CHLORIDE Usage And Synthesis

Uses

Methyl oxalyl chloride is an important organic intermediate (building block) to synthetize substituted methyl oxalyl products. It can be used for regioselective synthesis of fused coumarins, cyclization to form substituted isoxazoles and heterocycles, intramolecular Wittig reactions, silyl enol ether acylation, and iron-mediated cleavage of C-C bonds.

Chemical Properties

CLEAR LIQUID

Uses

Methyl oxalyl chloride is used as a synthetic reagent. It serves as a reagent in the synthesis of fused coumarins, substituted isoxazoles and heterocycles. Further, it is used in intramolecular Wittig reactions, and iron-mediated cleavage of C-C bonds.

Uses

Reactant involved in:

• Regioselective synthesis of fused coumarins
• Cyclization to form substituted isoxazoles and heterocycles
• Intramolecular Wittig reactions
• Silyl enol ether acylation
• Iron-mediated cleavage of C-C bonds

METHYL OXALYL CHLORIDE(5781-53-3)Related Product Information

• Thiourea dioxide
• Methyl vinyl sulfone
• Benzenesulfonyl chloride
• Di-tert-butyl peroxide
• Dichloromethane
• Cocamidopropyl betaine
• 4-tert-Butyltoluene
• 2-Bromoethanol
• N-Methylpropionamide
• Magnesium oxide
• Dimethyl oxalate
• DL-Dithiothreitol
• Oxalyl chloride
• Valeryl chloride
• Ethyl oxalyl monochloride
• METHYL OXALYL CHLORIDE
• CHLOROOXOACETIC ACID 4-NITROPHENYL ESTER
• ACD