2-Bromoethanol
2-Bromoethanol Basic information
- Product Name:
- 2-Bromoethanol
- Synonyms:
-
- 2-Bromo Ethenol
- 2-bromo-1-ethanol
- 2-BROMOETHANOL
- ETHYLENE BROMOHYDRIN
- BROMOETHANOL-2
- beta-Bromoethyl alcohol
- 2-BROMOETHANOL, 1X1ML, TOL, 2000UG/ML
- 2-BROMOETHANOL, 1000MG, NEAT
- CAS:
- 540-51-2
- MF:
- C2H5BrO
- MW:
- 124.96
- EINECS:
- 208-748-1
- Product Categories:
-
- Alcohols
- Building Blocks
- omega-Bromoalkanols
- omega-Functional Alkanols, Carboxylic Acids, Amines & Halides
- ASTM 5578: Analysis of Ethylene Oxide in AirAlphabetic
- C2 to C6
- A-BMethod Specific
- Alpha Sort
- ASTM Air Monitoring
- B
- BI - BZChemical Class
- Bromo
- Halogenated
- Volatiles/ Semivolatiles
- Pharmaceutical Intermediates
- Chemical Synthesis
- Organic Building Blocks
- Oxygen Compounds
- Mol File:
- 540-51-2.mol
2-Bromoethanol Chemical Properties
- Melting point:
- -80 °C
- Boiling point:
- 56-57 °C/20 mmHg (lit.)
- Density
- 1.763 g/mL at 25 °C (lit.)
- vapor density
- 4.3 (vs air)
- vapor pressure
- 2.4 mm Hg ( 20 °C)
- refractive index
- n20/D 1.492(lit.)
- Flash point:
- >230 °F
- storage temp.
- 2-8°C
- solubility
- 1-5 g/100 mL at 19°C
- form
- Liquid
- pka
- 13.82±0.10(Predicted)
- color
- Clear colorless to yellow
- Specific Gravity
- 1.7629 (20/4℃)
- Water Solubility
- 1-5 g/100 mL at 19 ºC
- Sensitive
- Light Sensitive
- Merck
- 14,3792
- BRN
- 878140
- Stability:
- Stable, but probably light sensitive. Hygroscopic. Incompatible with strong oxidizing agents. Flammable. Forms an azeotrope with water.
- InChIKey
- LDLCZOVUSADOIV-UHFFFAOYSA-N
- CAS DataBase Reference
- 540-51-2(CAS DataBase Reference)
- NIST Chemistry Reference
- Ethanol, 2-bromo-(540-51-2)
- EPA Substance Registry System
- 2-Bromoethanol (540-51-2)
Safety Information
- Hazard Codes
- T,T+,Xn,F
- Risk Statements
- 23/24/25-34-40-36/37/38-26/27/28-10-67-65-48/20-38-11-63
- Safety Statements
- 26-36/37/39-45-28A-16-62-36/37
- RIDADR
- UN 2922 8/PG 2
- WGK Germany
- 3
- RTECS
- KJ8225000
- TSCA
- Yes
- HazardClass
- 6.1
- PackingGroup
- II
- HS Code
- 29055900
MSDS
- Language:English Provider:2-Bromo-1-ethanol
- Language:English Provider:ACROS
- Language:English Provider:SigmaAldrich
- Language:English Provider:ALFA
2-Bromoethanol Usage And Synthesis
Toxicity
2-Bromoethanol can damage human body. The invasive ways of 2-bromoethanol include inhalation, ingestion and percutaneous absorption. 2-Bromoethanol has strong irritation to mucosa, upper respiratory tract, eyes and skin. Inhalation of 2-bromoethanol can cause death due to spasm, inflammation and edema of larynx and bronchus, chemical pneumonia and pulmonary edema. The manifestations of 2-bromoethanol poisoning include burning sensation, cough, wheezing, laryngitis, shortness of breath, headache, nausea and vomiting.
Chemical Properties
2-Bromoethanol is a colorless or light yellow hygroscopic liquid with relatively stable and toxic chemical properties. It plays a role in industrial and chemical experiments. It shall be stored in a ventilated, low-temperature and dry warehouse and separated from oxidants, acids and food additives. It is miscible with water and forms an azeotrope with water. The boiling point is 99.1 ℃ (101.35kpa). The aqueous solution has a sweet burning taste. It can be miscible with most organic solvents such as ethanol and ether, but insoluble in petroleum ether. The hydrolysis of aqueous solution can be accelerated when it meets acid, alkali and heating.
Chemical Properties
colourless liquid
Uses
2-Bromoethanol is used in selective reduction of nitroarenes (PcFe(II)/NaBH4/2-bromoethanol catalyst system).
Uses
Ethylene bromohydrin is not used much forany commercial purpose. The risk of expo sure to this compound arises when ethyleneoxide reacts with hydrobromic acid.
Uses
2-Bromoethanol is utilized in selective reduction of nitroarenes. It is used as a solvent and organic synthetic raw material. It finds application in the synthesis of 2-piperidin-1-yl-ethanol by reacting with piperidine. It is used in selective reduction of nitroarenes.
General Description
Colorless to dark brown liquid. Sweet burning taste.
Air & Water Reactions
Hygroscopic. Water soluble.
Reactivity Profile
2-Bromoethanol forms an azeotrope with water; hydrolysis of aqueous solutions is accelerated by heat, alkalis and acids.
Hazard
Irritant to eyes and mucous membranes.
Health Hazard
The vapors of ethylene bromohydrin are anirritant to the eyes and mucous membranes.It is corrosive to the skin. Ingestion of thiscompound can produce moderate to severetoxic effects. The target organs are the CNS,gastrointestinal tract, and liver. The lethaldose in mice by the intraperitoneal route was80 mg/kg.
Ethylene bromohydrin manifested car cinogenicity in test animals. It caused tumorsin lungs and the gastrointestinal tract in micefrom intraperitoneal (150 mg/kg/8 weeks)and oral (43 mg/kg/80 weeks) dosages,respectively. It is a mutagen, positive to thehistidine reversion–Ames test.
Fire Hazard
2-Bromoethanol is combustible.
Safety Profile
Poison by intraperitoneal route. Questionable carcinogen with experimental neoplastigenic and tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic fumes of Br-. See also
Waste Disposal
Ethylene bromohydrin is mixed with a combustible solvent and burned in a chemicalincinerator.
2-Bromoethanol Preparation Products And Raw materials
Preparation Products
Raw materials
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2-Bromoethanol(540-51-2)Related Product Information
- Ethanol
- Ethyl acetate
- Ethylene glycol
- Bromoacetaldehyde diethyl acetal
- Ethylene carbonate
- Monoethanolamine
- Diethanolamine
- ETHYLENE OXIDE
- ETHYLENE
- Ethylene glycol diacetate
- Ethyl bromoacetate
- Ethyl 2-bromovalerate
- Ethyl 2-bromohexanoate
- Methyl bromoacetate
- Ethyl 2-bromoheptanoate
- 1-BROMO-2,2-DIMETHOXYPROPANE
- Benzyl 2-bromoacetate
- Bromine